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ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner.
Brosnan-Cashman JA, Yuan M, Graham MK, Rizzo AJ, Myers KM, Davis C, Zhang R, Esopi DM, Raabe EH, Eberhart CG, Heaphy CM, Meeker AK. Brosnan-Cashman JA, et al. Among authors: rizzo aj. PLoS One. 2018 Sep 18;13(9):e0204159. doi: 10.1371/journal.pone.0204159. eCollection 2018. PLoS One. 2018. PMID: 30226859 Free PMC article.
Cocaine use may induce telomere shortening in individuals with HIV infection.
Lai S, Heaphy CM, Rizzo AJ, Celentano DD, Gerstenblith G, Li J, Moore RD, Treisman G, Chen S, Foster P, Kickler T, Lai H. Lai S, et al. Among authors: rizzo aj. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt A):11-17. doi: 10.1016/j.pnpbp.2018.01.015. Epub 2018 Feb 2. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29410247 Free PMC article.
The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.
Diplas BH, He X, Brosnan-Cashman JA, Liu H, Chen LH, Wang Z, Moure CJ, Killela PJ, Loriaux DB, Lipp ES, Greer PK, Yang R, Rizzo AJ, Rodriguez FJ, Friedman AH, Friedman HS, Wang S, He Y, McLendon RE, Bigner DD, Jiao Y, Waitkus MS, Meeker AK, Yan H. Diplas BH, et al. Among authors: rizzo aj. Nat Commun. 2018 May 25;9(1):2087. doi: 10.1038/s41467-018-04448-6. Nat Commun. 2018. PMID: 29802247 Free PMC article.
TERT promoter mutations in solitary fibrous tumour.
Demicco EG, Wani K, Ingram D, Wagner M, Maki RG, Rizzo A, Meeker A, Lazar AJ, Wang WL. Demicco EG, et al. Among authors: rizzo a. Histopathology. 2018 Nov;73(5):843-851. doi: 10.1111/his.13703. Epub 2018 Sep 19. Histopathology. 2018. PMID: 29985536
Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence.
Tomasetti C, Poling J, Roberts NJ, London NR Jr, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B. Tomasetti C, et al. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20482-20488. doi: 10.1073/pnas.1905722116. Epub 2019 Sep 23. Proc Natl Acad Sci U S A. 2019. PMID: 31548407 Free PMC article.
Functional Loss of ATRX and TERC Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells.
Graham MK, Kim J, Da J, Brosnan-Cashman JA, Rizzo A, Baena Del Valle JA, Chia L, Rubenstein M, Davis C, Zheng Q, Cope L, Considine M, Haffner MC, De Marzo AM, Meeker AK, Heaphy CM. Graham MK, et al. Mol Cancer Res. 2019 Dec;17(12):2480-2491. doi: 10.1158/1541-7786.MCR-19-0654. Epub 2019 Oct 14. Mol Cancer Res. 2019. PMID: 31611308 Free PMC article.
DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.
Pinto LM, Pailas A, Bondarchenko M, Sharma AB, Neumann K, Rizzo AJ, Jeanty C, Nicot N, Racca C, Graham MK, Naughton C, Liu Y, Chen CL, Meakin PJ, Gilbert N, Britton S, Meeker AK, Heaphy CM, Larminat F, Van Dyck E. Pinto LM, et al. Among authors: rizzo aj. Nucleic Acids Res. 2024 Feb 9;52(3):1136-1155. doi: 10.1093/nar/gkad1141. Nucleic Acids Res. 2024. PMID: 38038252 Free PMC article.
38 results