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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1983 1
1984 2
1987 1
1992 1
1993 4
1994 3
1996 2
1997 3
1998 2
1999 4
2000 7
2001 4
2002 7
2003 2
2004 2
2005 3
2006 5
2007 9
2008 8
2009 14
2010 12
2011 10
2012 10
2013 12
2014 18
2015 13
2016 19
2017 19
2018 26
2019 21
2020 30
2021 27
2022 29
2023 37
2024 16

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328 results

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Page 1
Modeling the ACMG/AMP variant classification guidelines as a Bayesian classification framework.
Tavtigian SV, Greenblatt MS, Harrison SM, Nussbaum RL, Prabhu SA, Boucher KM, Biesecker LG; ClinGen Sequence Variant Interpretation Working Group (ClinGen SVI). Tavtigian SV, et al. Genet Med. 2018 Sep;20(9):1054-1060. doi: 10.1038/gim.2017.210. Epub 2018 Jan 4. Genet Med. 2018. PMID: 29300386 Free PMC article.
PURPOSE: We evaluated the American College of Medical Genetics and Genomics/Association for Molecular Pathology (ACMG/AMP) variant pathogenicity guidelines for internal consistency and compatibility with Bayesian statistical reasoning. METHODS: The ACMG/AMP criteria were t …
PURPOSE: We evaluated the American College of Medical Genetics and Genomics/Association for Molecular Pathology (ACMG/AMP) variant pathogeni …
Key tips for teaching in the clinical setting.
Burgess A, van Diggele C, Roberts C, Mellis C. Burgess A, et al. BMC Med Educ. 2020 Dec 3;20(Suppl 2):463. doi: 10.1186/s12909-020-02283-2. BMC Med Educ. 2020. PMID: 33272257 Free PMC article. Review.
These patient-based tutorials introduce students to the clinical environment in a supervised and structured manner, providing opportunities to participate in communication skills, history taking, physical examination, clinical reasoning, diagnosis and management. It is onl …
These patient-based tutorials introduce students to the clinical environment in a supervised and structured manner, providing opportunities …
Naturally occurring T cell mutations enhance engineered T cell therapies.
Garcia J, Daniels J, Lee Y, Zhu I, Cheng K, Liu Q, Goodman D, Burnett C, Law C, Thienpont C, Alavi J, Azimi C, Montgomery G, Roybal KT, Choi J. Garcia J, et al. Nature. 2024 Feb;626(7999):626-634. doi: 10.1038/s41586-024-07018-7. Epub 2024 Feb 7. Nature. 2024. PMID: 38326614
In human T cell cancers, evolution of the disease positively selects for mutations that improve fitness of T cells in challenging situations analogous to those faced by therapeutic T cells. Therefore, we reasoned that these mutations could be co-opted to improve T cell the …
In human T cell cancers, evolution of the disease positively selects for mutations that improve fitness of T cells in challenging situations …
Evaluating Medical Decision-Making Capacity in Practice.
Barstow C, Shahan B, Roberts M. Barstow C, et al. Am Fam Physician. 2018 Jul 1;98(1):40-46. Am Fam Physician. 2018. PMID: 30215955 Free article.
Patients have medical decision-making capacity if they can demonstrate understanding of the situation, appreciation of the consequences of their decision, and reasoning in their thought process, and if they can communicate their wishes. ...
Patients have medical decision-making capacity if they can demonstrate understanding of the situation, appreciation of the consequences of t …
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease.
Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich R, Nave KA, Stassart RM. Schäffner E, et al. Nat Neurosci. 2023 Jul;26(7):1218-1228. doi: 10.1038/s41593-023-01366-9. Epub 2023 Jun 29. Nat Neurosci. 2023. PMID: 37386131 Free PMC article.
Given that axonal pathology in multiple sclerosis is already visible at early disease stages, before overt demyelination, we reasoned that autoimmune inflammation may disrupt oligodendroglial support mechanisms and hence primarily affect axons insulated by myelin. ...
Given that axonal pathology in multiple sclerosis is already visible at early disease stages, before overt demyelination, we reasoned …
25th Annual Computational Neuroscience Meeting: CNS-2016.
Sharpee TO, Destexhe A, Kawato M, Sekulić V, Skinner FK, Wójcik DK, Chintaluri C, Cserpán D, Somogyvári Z, Kim JK, Kilpatrick ZP, Bennett MR, Josić K, Elices I, Arroyo D, Levi R, Rodriguez FB, Varona P, Hwang E, Kim B, Han HB, Kim T, McKenna JT, Brown RE, McCarley RW, Choi JH, Rankin J, Popp PO, Rinzel J, Tabas A, Rupp A, Balaguer-Ballester E, Maturana MI, Grayden DB, Cloherty SL, Kameneva T, Ibbotson MR, Meffin H, Koren V, Lochmann T, Dragoi V, Obermayer K, Psarrou M, Schilstra M, Davey N, Torben-Nielsen B, Steuber V, Ju H, Yu J, Hines ML, Chen L, Yu Y, Kim J, Leahy W, Shlizerman E, Birgiolas J, Gerkin RC, Crook SM, Viriyopase A, Memmesheimer RM, Gielen S, Dabaghian Y, DeVito J, Perotti L, Kim AJ, Fenk LM, Cheng C, Maimon G, Zhao C, Widmer Y, Sprecher S, Senn W, Halnes G, Mäki-Marttunen T, Keller D, Pettersen KH, Andreassen OA, Einevoll GT, Yamada Y, Steyn-Ross ML, Alistair Steyn-Ross D, Mejias JF, Murray JD, Kennedy H, Wang XJ, Kruscha A, Grewe J, Benda J, Lindner B, Badel L, Ohta K, Tsuchimoto Y, Kazama H, Kahng B, Tam ND, Pollonini L, Zouridakis G, Soh J, Kim D, Yoo M, Palmer SE, Culmone V, Bojak I, Ferrario A, Merrison-Hort R, Borisyuk R, Kim CS, Tezuka T, Joo P, Rho YA, Burt… See abstract for full author list ➔ Sharpee TO, et al. BMC Neurosci. 2016 Aug 18;17 Suppl 1(Suppl 1):54. doi: 10.1186/s12868-016-0283-6. BMC Neurosci. 2016. PMID: 27534393 Free PMC article.
Torres, Fabiano Baroni, Roberto Latorre, Pablo Varona P40 Different roles for transient and sustained activity during active visual processing Bart Gips, Eric Lowet, Mark J. Roberts, Peter de Weerd, Ole Jensen, Jan van der Eerden P41 Scale-free functional networks of 2D Is …
Torres, Fabiano Baroni, Roberto Latorre, Pablo Varona P40 Different roles for transient and sustained activity during active visual processi …
Wearable-Based Affect Recognition-A Review.
Schmidt P, Reiss A, Dürichen R, Laerhoven KV. Schmidt P, et al. Sensors (Basel). 2019 Sep 20;19(19):4079. doi: 10.3390/s19194079. Sensors (Basel). 2019. PMID: 31547220 Free PMC article. Review.
Affect recognition research aims to detect the affective state of a person based on observables, with the goal to, for example, provide reasoning for the person's decision making or to support mental wellbeing (e.g., stress monitoring). ...
Affect recognition research aims to detect the affective state of a person based on observables, with the goal to, for example, provide r …
The Crisis in Standards of Care.
Kaebnick GE. Kaebnick GE. Hastings Cent Rep. 2021 Sep;51(5):2. doi: 10.1002/hast.1279. Hastings Cent Rep. 2021. PMID: 34529854
This claim is elaborated in the article by Alex Rajczi and colleagues, who argue that identifying and applying the public's will-a process they call "political reasoning"-is the core work in developing CSC. Five commentaries-two coauthored, by Douglas B. ...Wynia, and thre …
This claim is elaborated in the article by Alex Rajczi and colleagues, who argue that identifying and applying the public's will-a process t …
Evidence Brief: The Quality of Care Provided by Advanced Practice Nurses [Internet].
McCleery E, Christensen V, Peterson K, Humphrey L, Helfand M. McCleery E, et al. Washington (DC): Department of Veterans Affairs (US); 2014 Sep. Washington (DC): Department of Veterans Affairs (US); 2014 Sep. PMID: 27606392 Free Books & Documents. Review.
Other arguments made by advocates for APRNs about the adverse effects of SOP restrictions are based on hypothetical reasoning or on anecdotes concerning inefficient use of time and, in some cases, delay in needed care because a physician's approval was required to prescrib …
Other arguments made by advocates for APRNs about the adverse effects of SOP restrictions are based on hypothetical reasoning or on a …
NCCN Evidence Blocks.
Carlson RW, Jonasch E. Carlson RW, et al. J Natl Compr Canc Netw. 2016 May;14(5 Suppl):616-9. doi: 10.6004/jnccn.2016.0177. J Natl Compr Canc Netw. 2016. PMID: 27226499
At a glance, patients and providers can understand how a given treatment was assessed by the NCCN Guidelines Panel and get a sense of how a given treatment may match individual needs and preferences. Robert W. Carlson, MD, CEO of NCCN, described the reasoning behind …
At a glance, patients and providers can understand how a given treatment was assessed by the NCCN Guidelines Panel and get a sense of how a …
328 results