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ARID1B is a specific vulnerability in ARID1A-mutant cancers.
Helming KC, Wang X, Wilson BG, Vazquez F, Haswell JR, Manchester HE, Kim Y, Kryukov GV, Ghandi M, Aguirre AJ, Jagani Z, Wang Z, Garraway LA, Hahn WC, Roberts CW. Helming KC, et al. Among authors: roberts cw. Nat Med. 2014 Mar;20(3):251-4. doi: 10.1038/nm.3480. Epub 2014 Feb 23. Nat Med. 2014. PMID: 24562383 Free PMC article.
The SWI/SNF complex--chromatin and cancer.
Roberts CW, Orkin SH. Roberts CW, et al. Nat Rev Cancer. 2004 Feb;4(2):133-42. doi: 10.1038/nrc1273. Nat Rev Cancer. 2004. PMID: 14964309 Review. No abstract available.
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway.
Jagani Z, Mora-Blanco EL, Sansam CG, McKenna ES, Wilson B, Chen D, Klekota J, Tamayo P, Nguyen PT, Tolstorukov M, Park PJ, Cho YJ, Hsiao K, Buonamici S, Pomeroy SL, Mesirov JP, Ruffner H, Bouwmeester T, Luchansky SJ, Murtie J, Kelleher JF, Warmuth M, Sellers WR, Roberts CW, Dorsch M. Jagani Z, et al. Among authors: roberts cw. Nat Med. 2010 Dec;16(12):1429-33. doi: 10.1038/nm.2251. Epub 2010 Nov 14. Nat Med. 2010. PMID: 21076395 Free PMC article.
SWI/SNF nucleosome remodellers and cancer.
Wilson BG, Roberts CW. Wilson BG, et al. Among authors: roberts cw. Nat Rev Cancer. 2011 Jun 9;11(7):481-92. doi: 10.1038/nrc3068. Nat Rev Cancer. 2011. PMID: 21654818 Review.
TCR-dependent transformation of mature memory phenotype T cells in mice.
Wang X, Werneck MB, Wilson BG, Kim HJ, Kluk MJ, Thom CS, Wischhusen JW, Evans JA, Jesneck JL, Nguyen P, Sansam CG, Cantor H, Roberts CW. Wang X, et al. Among authors: roberts cw. J Clin Invest. 2011 Oct;121(10):3834-45. doi: 10.1172/JCI37210. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926465 Free PMC article.
289 results