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Hyperglycemia Enhances Cancer Immune Evasion by Inducing Alternative Macrophage Polarization through Increased O-GlcNAcylation.
Cancer Immunol Res. 2020 Oct;8(10):1262-1272. doi: 10.1158/2326-6066.CIR-19-0904. Epub 2020 Jul 27.
Cancer Immunol Res. 2020.
PMID: 32819969
Tumor-associated carbohydrates and immunomodulatory lectins as targets for cancer immunotherapy.
Rodrigues Mantuano N, Natoli M, Zippelius A, Läubli H.
Rodrigues Mantuano N, et al.
J Immunother Cancer. 2020 Oct;8(2):e001222. doi: 10.1136/jitc-2020-001222.
J Immunother Cancer. 2020.
PMID: 33020245
Free PMC article.
Review.
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Melanoma clonal heterogeneity leads to secondary resistance after adoptive cell therapy with tumor-infiltrating lymphocytes.
König D, Sandholzer M, Uzun S, Zingg A, Ritschard R, Thut H, Glatz K, Kappos EA, Schaefer DJ, Kettelhack C, Passweg JR, Holbro A, Baur K, Medinger M, Buser A, Lardinois D, Jeker LT, Khanna N, Stenner F, Kasenda B, Homicsko K, Matter M, Rodrigues Mantuano N, Zippelius A, Läubli H.
König D, et al. Among authors: rodrigues mantuano n.
Cancer Immunol Res. 2024 Apr 17. doi: 10.1158/2326-6066.CIR-23-0757. Online ahead of print.
Cancer Immunol Res. 2024.
PMID: 38631025
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Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma.
Schmassmann P, Roux J, Buck A, Tatari N, Hogan S, Wang J, Rodrigues Mantuano N, Wieboldt R, Lee S, Snijder B, Kaymak D, Martins TA, Ritz MF, Shekarian T, McDaid M, Weller M, Weiss T, Läubli H, Hutter G.
Schmassmann P, et al. Among authors: rodrigues mantuano n.
Sci Transl Med. 2023 Jul 19;15(705):eadf5302. doi: 10.1126/scitranslmed.adf5302. Epub 2023 Jul 19.
Sci Transl Med. 2023.
PMID: 37467314
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Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade.
Stanczak MA, Rodrigues Mantuano N, Kirchhammer N, Sanin DE, Jacob F, Coelho R, Everest-Dass AV, Wang J, Trefny MP, Monaco G, Bärenwaldt A, Gray MA, Petrone A, Kashyap AS, Glatz K, Kasenda B, Normington K, Broderick J, Peng L, Pearce OMT, Pearce EL, Bertozzi CR, Zippelius A, Läubli H.
Stanczak MA, et al. Among authors: rodrigues mantuano n.
Sci Transl Med. 2022 Nov 2;14(669):eabj1270. doi: 10.1126/scitranslmed.abj1270. Epub 2022 Nov 2.
Sci Transl Med. 2022.
PMID: 36322632
Free PMC article.
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