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Cholesterol access in cellular membranes controls Hedgehog signaling.
Radhakrishnan A, Rohatgi R, Siebold C. Radhakrishnan A, et al. Among authors: rohatgi r. Nat Chem Biol. 2020 Dec;16(12):1303-1313. doi: 10.1038/s41589-020-00678-2. Epub 2020 Nov 16. Nat Chem Biol. 2020. PMID: 33199907 Free PMC article. Review.
Patching the gaps in Hedgehog signalling.
Rohatgi R, Scott MP. Rohatgi R, et al. Nat Cell Biol. 2007 Sep;9(9):1005-9. doi: 10.1038/ncb435. Nat Cell Biol. 2007. PMID: 17762891
Oxysterols are allosteric activators of the oncoprotein Smoothened.
Nachtergaele S, Mydock LK, Krishnan K, Rammohan J, Schlesinger PH, Covey DF, Rohatgi R. Nachtergaele S, et al. Among authors: rohatgi r. Nat Chem Biol. 2012 Jan 8;8(2):211-20. doi: 10.1038/nchembio.765. Nat Chem Biol. 2012. PMID: 22231273 Free PMC article.
G-protein-coupled receptors, Hedgehog signaling and primary cilia.
Mukhopadhyay S, Rohatgi R. Mukhopadhyay S, et al. Among authors: rohatgi r. Semin Cell Dev Biol. 2014 Sep;33:63-72. doi: 10.1016/j.semcdb.2014.05.002. Epub 2014 May 17. Semin Cell Dev Biol. 2014. PMID: 24845016 Free PMC article. Review.
163 results