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Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors.
Alaimo A, Lorenzoni M, Ambrosino P, Bertossi A, Bisio A, Macchia A, Zoni E, Genovesi S, Cambuli F, Foletto V, De Felice D, Soldovieri MV, Mosca I, Gandolfi F, Brunelli M, Petris G, Cereseto A, Villarroel A, Thalmann G, Carbone FG, Kruithof-de Julio M, Barbareschi M, Romanel A, Taglialatela M, Lunardi A. Alaimo A, et al. Among authors: romanel a. Cell Death Dis. 2020 Dec 7;11(12):1039. doi: 10.1038/s41419-020-03256-5. Cell Death Dis. 2020. PMID: 33288740 Free PMC article.
Inherited determinants of early recurrent somatic mutations in prostate cancer.
Romanel A, Garritano S, Stringa B, Blattner M, Dalfovo D, Chakravarty D, Soong D, Cotter KA, Petris G, Dhingra P, Gasperini P, Cereseto A, Elemento O, Sboner A, Khurana E, Inga A, Rubin MA, Demichelis F. Romanel A, et al. Nat Commun. 2017 Jun 29;8(1):48. doi: 10.1038/s41467-017-00046-0. Nat Commun. 2017. PMID: 28663546 Free PMC article.
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Casini A, Olivieri M, Petris G, Montagna C, Reginato G, Maule G, Lorenzin F, Prandi D, Romanel A, Demichelis F, Inga A, Cereseto A. Casini A, et al. Among authors: romanel a. Nat Biotechnol. 2018 Mar;36(3):265-271. doi: 10.1038/nbt.4066. Epub 2018 Jan 29. Nat Biotechnol. 2018. PMID: 29431739 Free PMC article.
Intra-epithelial non-canonical Activin A signaling safeguards prostate progenitor quiescence.
Cambuli F, Foletto V, Alaimo A, De Felice D, Gandolfi F, Palumbieri MD, Zaffagni M, Genovesi S, Lorenzoni M, Celotti M, Bertossio E, Mazzero G, Bertossi A, Bisio A, Berardinelli F, Antoccia A, Gaspari M, Barbareschi M, Fiorentino M, Shen MM, Loda M, Romanel A, Lunardi A. Cambuli F, et al. Among authors: romanel a. EMBO Rep. 2022 May 4;23(5):e54049. doi: 10.15252/embr.202154049. Epub 2022 Mar 7. EMBO Rep. 2022. PMID: 35253958 Free PMC article.
ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation.
Lorenzoni M, De Felice D, Beccaceci G, Di Donato G, Foletto V, Genovesi S, Bertossi A, Cambuli F, Lorenzin F, Savino A, Avalle L, Cimadamore A, Montironi R, Weber V, Carbone FG, Barbareschi M, Demichelis F, Romanel A, Poli V, Del Sal G, Julio MK, Gaspari M, Alaimo A, Lunardi A. Lorenzoni M, et al. Among authors: romanel a. Cancer Lett. 2022 May 28;534:215612. doi: 10.1016/j.canlet.2022.215612. Epub 2022 Mar 5. Cancer Lett. 2022. PMID: 35259458 Free PMC article.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Prakasam R, Bonadiman A, Andreotti R, Zuccaro E, Dalfovo D, Marchioretti C, Tripathy D, Petris G, Anderson EN, Migazzi A, Tosatto L, Cereseto A, Battaglioli E, Sorarù G, Lim WF, Rinaldi C, Sambataro F, Pourshafie N, Grunseich C, Romanel A, Pandey UB, Contestabile A, Ronzitti G, Basso M, Pennuto M. Prakasam R, et al. Among authors: romanel a. Nat Commun. 2023 Feb 6;14(1):603. doi: 10.1038/s41467-023-36186-9. Nat Commun. 2023. PMID: 36746939 Free PMC article.
59 results