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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1979 1
1984 1
1986 1
1993 1
1994 1
1995 3
1998 6
1999 4
2000 5
2001 9
2002 10
2003 7
2004 13
2005 7
2006 19
2007 13
2008 12
2009 15
2010 24
2011 27
2012 40
2013 37
2014 40
2015 57
2016 42
2017 69
2018 57
2019 62
2020 56
2021 69
2022 63
2023 51
2024 27

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773 results

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Page 1
Rora Regulates Neutrophil Migration and Activation in Zebrafish.
Hsu AY, Wang T, Syahirah R, Liu S, Li K, Zhang W, Wang J, Cao Z, Tian S, Matosevic S, Staiger CJ, Wan J, Deng Q. Hsu AY, et al. Front Immunol. 2022 Mar 4;13:756034. doi: 10.3389/fimmu.2022.756034. eCollection 2022. Front Immunol. 2022. PMID: 35309302 Free PMC article.
Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in AD and Rosacea.
Zhang H, Zhang Y, Li Y, Wang Y, Yan S, Xu S, Deng Z, Yang X, Xie H, Li J. Zhang H, et al. Front Immunol. 2021 Nov 23;12:756550. doi: 10.3389/fimmu.2021.756550. eCollection 2021. Front Immunol. 2021. PMID: 34899707 Free PMC article.
Among the 113 predicted drugs, melatonin (MLT) was co-associated with both RORA and IFN-gamma in AD and rosacea. Subsequently, network pharmacology analysis identified 19 pharmacological targets of MLT and demonstrated that MLT could help in treating AD/rosacea partly by m …
Among the 113 predicted drugs, melatonin (MLT) was co-associated with both RORA and IFN-gamma in AD and rosacea. Subsequently, networ …
RORA alleviates LPS-induced apoptosis of renal epithelial cells by promoting PGC-1alpha transcription.
Li D, Liu G, Wu Y. Li D, et al. Clin Exp Nephrol. 2022 Jun;26(6):512-521. doi: 10.1007/s10157-022-02184-2. Epub 2022 Feb 23. Clin Exp Nephrol. 2022. PMID: 35195816 Free PMC article.
RORA drove the transcription of PGC-1alpha by binding PGC-1alpha promoter. Knockdown of PGC-1alpha offset the reduction in HK-2 cell injury caused by overexpression of RORA. CONCLUSION: RORA reduces LPS-induced apoptosis of renal epithelial cells by promoting …
RORA drove the transcription of PGC-1alpha by binding PGC-1alpha promoter. Knockdown of PGC-1alpha offset the reduction in HK-2 cell …
Mapping Rora expression in resting and activated CD4+ T cells.
Haim-Vilmovsky L, Henriksson J, Walker JA, Miao Z, Natan E, Kar G, Clare S, Barlow JL, Charidemou E, Mamanova L, Chen X, Proserpio V, Pramanik J, Woodhouse S, Protasio AV, Efremova M, Griffin JL, Berriman M, Dougan G, Fisher J, Marioni JC, McKenzie ANJ, Teichmann SA. Haim-Vilmovsky L, et al. PLoS One. 2021 May 18;16(5):e0251233. doi: 10.1371/journal.pone.0251233. eCollection 2021. PLoS One. 2021. PMID: 34003838 Free PMC article.
The transcription factor Rora has been shown to be important for the development of ILC2 and the regulation of ILC3, macrophages and Treg cells. ...We dissect the function of Rora using overexpression and a CD4-conditional Rora-knockout mouse, as well as a …
The transcription factor Rora has been shown to be important for the development of ILC2 and the regulation of ILC3, macrophages and …
RORA polymorphisms are risk factors for allergic rhinitis susceptibility in the Shaanxi Han population.
Lian P, Du X, Liu X, Ruan W, Liu Y, Wang H. Lian P, et al. Int Immunopharmacol. 2022 Jul;108:108874. doi: 10.1016/j.intimp.2022.108874. Epub 2022 May 26. Int Immunopharmacol. 2022. PMID: 35636076
Genetic predisposition is the most important factor in the progression of AR. Previous studies have indicated that RORA is involved in the occurrence of AR. The present study aimed to determine the roles of RORA polymorphisms in AR susceptibility. METHODS: Periphera …
Genetic predisposition is the most important factor in the progression of AR. Previous studies have indicated that RORA is involved i …
Maternal diabetes-mediated RORA suppression contributes to gastrointestinal symptoms in autism-like mouse offspring.
Xiao L, Wang M, Zhang W, Song Y, Zeng J, Li H, Yu H, Li L, Gao P, Yao P. Xiao L, et al. BMC Neurosci. 2022 Feb 14;23(1):8. doi: 10.1186/s12868-022-00693-0. BMC Neurosci. 2022. PMID: 35164690 Free PMC article.
BACKGROUND: Retinoic acid-related orphan receptor alpha (RORA) has been reported to be suppressed in autistic patients and is associated with autism spectrum disorders (ASD), although the potential role and mechanism of RORA on gastrointestinal (GI) symptoms in ASD …
BACKGROUND: Retinoic acid-related orphan receptor alpha (RORA) has been reported to be suppressed in autistic patients and is associa …
POU6F1 cooperates with RORA to suppress the proliferation of lung adenocarcinoma by downregulation HIF1A signaling pathway.
Xiao W, Geng W, Zhou M, Xu J, Wang S, Huang Q, Sun Y, Li Y, Yang G, Jin Y. Xiao W, et al. Cell Death Dis. 2022 May 3;13(5):427. doi: 10.1038/s41419-022-04857-y. Cell Death Dis. 2022. PMID: 35504868 Free PMC article.
Mechanistically, POU6F1 bound and stabilized retinoid-related orphan receptor alpha (RORA) to exert the transcriptional inhibition of hypoxia-inducible factor 1-alpha (HIF1A) and alter the expression of HIF1A signaling pathway-associated genes, including ENO1, PDK1, and PR …
Mechanistically, POU6F1 bound and stabilized retinoid-related orphan receptor alpha (RORA) to exert the transcriptional inhibition of …
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Zhao J, Jiang Y, Chen L, Ma Y, Zhang H, Zhou J, Li H, Jing Z. Zhao J, et al. Front Oncol. 2021 Aug 2;11:699933. doi: 10.3389/fonc.2021.699933. eCollection 2021. Front Oncol. 2021. PMID: 34408982 Free PMC article.
We further confirmed RORA was downregulated in GBM. Thus, we determined whether RORA was involved in the migration, invasion, and EMT of GBM. ...We found that RORA inhibited the migration, invasion, and EMT of GBM. CASC2 could bind to, maintain the stability, …
We further confirmed RORA was downregulated in GBM. Thus, we determined whether RORA was involved in the migration, invasion, …
RORA rs8042149 polymorphism moderates the association between PTSD symptom severity and transverse temporal gyrus thickness in Han Chinese adults who lost their only child.
Qi R, Cao Z, Surento W, Zhang L, Qiu L, Xia Z, Ching CRK, Xu Q, Yin Y, Zhang LJ, Li L, Luo Y, Lu GM. Qi R, et al. J Affect Disord. 2022 Oct 1;314:318-324. doi: 10.1016/j.jad.2022.07.044. Epub 2022 Jul 22. J Affect Disord. 2022. PMID: 35878841
Although recent MRI studies identified brain structural deficits in RORA rs8042149 risk G allele carriers, the neural mechanism underlying RORA-related brain structural changes in PTSD remains poorly understood. ...Hierarchical linear regression was used to assess t …
Although recent MRI studies identified brain structural deficits in RORA rs8042149 risk G allele carriers, the neural mechanism under …
The suppressive functions of Rora in B lineage cell proliferation and BCR/ABL1-induced B-ALL pathogenesis.
Li N, Wang N, He W, Feng Y, Qiu Q, Qiu H, Zheng L, Yin Y, Wang B, Sun Y, Pan C, Sample KM, Huang J, Su Z, Li Z, Zhang H, Hu Y. Li N, et al. Int J Biol Sci. 2022 Mar 6;18(6):2277-2291. doi: 10.7150/ijbs.68939. eCollection 2022. Int J Biol Sci. 2022. PMID: 35414788 Free PMC article.
By using Rora(loxp/loxp) Mx-1-Cre mice, Rora was deleted in hematopoietic cells post Pipc induction. ...These results suggest a novel role for Rora in B cell development and Ph(+) leukemogenesis....
By using Rora(loxp/loxp) Mx-1-Cre mice, Rora was deleted in hematopoietic cells post Pipc induction. ...These results suggest …
773 results