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TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.
Chakrabarty P, Li A, Ladd TB, Strickland MR, Koller EJ, Burgess JD, Funk CC, Cruz PE, Allen M, Yaroshenko M, Wang X, Younkin C, Reddy J, Lohrer B, Mehrke L, Moore BD, Liu X, Ceballos-Diaz C, Rosario AM, Medway C, Janus C, Li HD, Dickson DW, Giasson BI, Price ND, Younkin SG, Ertekin-Taner N, Golde TE. Chakrabarty P, et al. Among authors: rosario am. J Exp Med. 2018 Sep 3;215(9):2247-2264. doi: 10.1084/jem.20180484. J Exp Med. 2018. PMID: 30158114 Free PMC article.
A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo.
Levites Y, O'Nuallain B, Puligedda RD, Ondrejcak T, Adekar SP, Chen C, Cruz PE, Rosario AM, Macy S, Mably AJ, Walsh DM, Vidal R, Solomon A, Brown D, Rowan MJ, Golde TE, Dessain SK. Levites Y, et al. Among authors: rosario am. J Neurosci. 2015 Apr 22;35(16):6265-76. doi: 10.1523/JNEUROSCI.5109-14.2015. J Neurosci. 2015. PMID: 25904780 Free PMC article.
Microglia-specific targeting by novel capsid-modified AAV6 vectors.
Rosario AM, Cruz PE, Ceballos-Diaz C, Strickland MR, Siemienski Z, Pardo M, Schob KL, Li A, Aslanidi GV, Srivastava A, Golde TE, Chakrabarty P. Rosario AM, et al. Mol Ther Methods Clin Dev. 2016 Apr 13;3:16026. doi: 10.1038/mtm.2016.26. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27308302 Free PMC article.
APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse Model.
Deyts C, Clutter M, Pierce N, Chakrabarty P, Ladd TB, Goddi A, Rosario AM, Cruz P, Vetrivel K, Wagner SL, Thinakaran G, Golde TE, Parent AT. Deyts C, et al. Among authors: rosario am. Cell Rep. 2019 Apr 30;27(5):1345-1355.e6. doi: 10.1016/j.celrep.2019.03.087. Cell Rep. 2019. PMID: 31042463 Free PMC article.
Il-10 signaling reduces survival in mouse models of synucleinopathy.
Cockey SG, McFarland KN, Koller EJ, Brooks MMT, Gonzalez De La Cruz E, Cruz PE, Ceballos-Diaz C, Rosario AM, Levites YR, Borchelt DR, Golde TE, Giasson BI, Chakrabarty P. Cockey SG, et al. Among authors: rosario am. NPJ Parkinsons Dis. 2021 Mar 19;7(1):30. doi: 10.1038/s41531-021-00169-8. NPJ Parkinsons Dis. 2021. PMID: 33741985 Free PMC article.
36 results