Rosen ED - Search Results

1

The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation.

Ahmad R, Al-Roub A, Kochumon S, Akther N, Thomas R, Kumari M, Koshy MS, Tiss A, Hannun YA, Tuomilehto J, Sindhu S, Rosen ED. Ahmad R, et al. Among authors: rosen ed. J Immunol. 2018 May 15;200(10):3599-3611. doi: 10.4049/jimmunol.1701552. Epub 2018 Apr 9. J Immunol. 2018. PMID: 29632147 Free PMC article.

2

Interferon regulatory factor 4 regulates obesity-induced inflammation through regulation of adipose tissue macrophage polarization.

Eguchi J, Kong X, Tenta M, Wang X, Kang S, Rosen ED. Eguchi J, et al. Among authors: rosen ed. Diabetes. 2013 Oct;62(10):3394-403. doi: 10.2337/db12-1327. Epub 2013 Jul 8. Diabetes. 2013. PMID: 23835343 Free PMC article.

3

IRF3 promotes adipose inflammation and insulin resistance and represses browning.

Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED. Kumari M, et al. Among authors: rosen ed. J Clin Invest. 2016 Aug 1;126(8):2839-54. doi: 10.1172/JCI86080. Epub 2016 Jul 11. J Clin Invest. 2016. PMID: 27400129 Free PMC article.

4

Simultaneous Transcriptional and Epigenomic Profiling from Specific Cell Types within Heterogeneous Tissues In Vivo.

Roh HC, Tsai LT, Lyubetskaya A, Tenen D, Kumari M, Rosen ED. Roh HC, et al. Among authors: rosen ed. Cell Rep. 2017 Jan 24;18(4):1048-1061. doi: 10.1016/j.celrep.2016.12.087. Cell Rep. 2017. PMID: 28122230 Free PMC article.

5

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction.

Kazak L, Chouchani ET, Stavrovskaya IG, Lu GZ, Jedrychowski MP, Egan DF, Kumari M, Kong X, Erickson BK, Szpyt J, Rosen ED, Murphy MP, Kristal BS, Gygi SP, Spiegelman BM. Kazak L, et al. Among authors: rosen ed. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):7981-7986. doi: 10.1073/pnas.1705406114. Epub 2017 Jun 19. Proc Natl Acad Sci U S A. 2017. PMID: 28630339 Free PMC article.

6

Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.

Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM. Kazak L, et al. Among authors: rosen ed. Cell Metab. 2017 Oct 3;26(4):660-671.e3. doi: 10.1016/j.cmet.2017.08.009. Epub 2017 Aug 24. Cell Metab. 2017. PMID: 28844881 Free PMC article.

7

Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding.

Shen Y, Roh HC, Kumari M, Rosen ED. Shen Y, et al. Among authors: rosen ed. Mol Metab. 2017 Oct;6(10):1150-1160. doi: 10.1016/j.molmet.2017.06.013. Epub 2017 Jun 29. Mol Metab. 2017. PMID: 29031716 Free PMC article.

8

Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity.

Roh HC, Tsai LTY, Shao M, Tenen D, Shen Y, Kumari M, Lyubetskaya A, Jacobs C, Dawes B, Gupta RK, Rosen ED. Roh HC, et al. Among authors: rosen ed. Cell Metab. 2018 May 1;27(5):1121-1137.e5. doi: 10.1016/j.cmet.2018.03.005. Epub 2018 Apr 12. Cell Metab. 2018. PMID: 29657031 Free PMC article.

9

Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling.

Roh HC, Kumari M, Taleb S, Tenen D, Jacobs C, Lyubetskaya A, Tsai LT, Rosen ED. Roh HC, et al. Among authors: rosen ed. Mol Metab. 2020 Dec;42:101086. doi: 10.1016/j.molmet.2020.101086. Epub 2020 Sep 28. Mol Metab. 2020. PMID: 32992037 Free PMC article.

10

Insulin-sensitizing effects of vitamin D repletion mediated by adipocyte vitamin D receptor: Studies in humans and mice.

Lontchi-Yimagou E, Kang S, Goyal A, Zhang K, You JY, Carey M, Jain S, Bhansali S, Kehlenbrink S, Guo P, Rosen ED, Kishore P, Hawkins M. Lontchi-Yimagou E, et al. Among authors: rosen ed. Mol Metab. 2020 Dec;42:101095. doi: 10.1016/j.molmet.2020.101095. Epub 2020 Oct 10. Mol Metab. 2020. PMID: 33045433 Free PMC article. Clinical Trial.

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