Rossman KL - Search Results

1

Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

Vigil D, Cherfils J, Rossman KL, Der CJ. Vigil D, et al. Among authors: rossman kl. Nat Rev Cancer. 2010 Dec;10(12):842-57. doi: 10.1038/nrc2960. Epub 2010 Nov 24. Nat Rev Cancer. 2010. PMID: 21102635 Free PMC article. Review.

2

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.

Snyder JT, Worthylake DK, Rossman KL, Betts L, Pruitt WM, Siderovski DP, Der CJ, Sondek J. Snyder JT, et al. Among authors: rossman kl. Nat Struct Biol. 2002 Jun;9(6):468-75. doi: 10.1038/nsb796. Nat Struct Biol. 2002. PMID: 12006984

3

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors.

Rossman KL, Der CJ, Sondek J. Rossman KL, et al. Nat Rev Mol Cell Biol. 2005 Feb;6(2):167-80. doi: 10.1038/nrm1587. Nat Rev Mol Cell Biol. 2005. PMID: 15688002 Review.

4

Signaling interplay in Ras superfamily function.

Mitin N, Rossman KL, Der CJ. Mitin N, et al. Among authors: rossman kl. Curr Biol. 2005 Jul 26;15(14):R563-74. doi: 10.1016/j.cub.2005.07.010. Curr Biol. 2005. PMID: 16051167 Free article. Review.

5

RAS isoforms and mutations in cancer at a glance.

Hobbs GA, Der CJ, Rossman KL. Hobbs GA, et al. Among authors: rossman kl. J Cell Sci. 2016 Apr 1;129(7):1287-92. doi: 10.1242/jcs.182873. Epub 2016 Mar 16. J Cell Sci. 2016. PMID: 26985062 Free PMC article. Review.

6

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease.

Cook DR, Rossman KL, Der CJ. Cook DR, et al. Among authors: rossman kl. Oncogene. 2014 Jul 31;33(31):4021-35. doi: 10.1038/onc.2013.362. Epub 2013 Sep 16. Oncogene. 2014. PMID: 24037532 Free PMC article. Review.

7

Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation.

Solski PA, Wilder RS, Rossman KL, Sondek J, Cox AD, Campbell SL, Der CJ. Solski PA, et al. Among authors: rossman kl. J Biol Chem. 2004 Jun 11;279(24):25226-33. doi: 10.1074/jbc.M313792200. Epub 2004 Apr 8. J Biol Chem. 2004. PMID: 15073184 Free article.

8

Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif.

Yohe ME, Rossman KL, Gardner OS, Karnoub AE, Snyder JT, Gershburg S, Graves LM, Der CJ, Sondek J. Yohe ME, et al. Among authors: rossman kl. J Biol Chem. 2007 May 4;282(18):13813-23. doi: 10.1074/jbc.M700185200. Epub 2007 Mar 2. J Biol Chem. 2007. PMID: 17337446 Free article.

9

Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.

Mitin N, Betts L, Yohe ME, Der CJ, Sondek J, Rossman KL. Mitin N, et al. Among authors: rossman kl. Nat Struct Mol Biol. 2007 Sep;14(9):814-23. doi: 10.1038/nsmb1290. Epub 2007 Aug 19. Nat Struct Mol Biol. 2007. PMID: 17704816 Free PMC article.

10

Oncogenic activity of Ect2 is regulated through protein kinase C iota-mediated phosphorylation.

Justilien V, Jameison L, Der CJ, Rossman KL, Fields AP. Justilien V, et al. Among authors: rossman kl. J Biol Chem. 2011 Mar 11;286(10):8149-8157. doi: 10.1074/jbc.M110.196113. Epub 2010 Dec 28. J Biol Chem. 2011. PMID: 21189248 Free PMC article.

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