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Treatment inferred from mutations identified using massive parallel sequencing leads to clinical benefit in some heavily pretreated cancer patients.
Zick A, Peretz T, Lotem M, Hubert A, Katz D, Temper M, Rottenberg Y, Uziely B, Nechushtan H, Meirovitz A, Sonnenblick A, Sapir E, Edelman D, Goldberg Y, Lossos A, Rosenberg S, Fried I, Finklstein R, Pikarsky E, Goldshmidt H. Zick A, et al. Among authors: rottenberg y. Medicine (Baltimore). 2017 May;96(20):e6931. doi: 10.1097/MD.0000000000006931. Medicine (Baltimore). 2017. PMID: 28514312 Free PMC article.
Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis.
Sonnenblick A, Shriki A, Galun E, Axelrod JH, Daum H, Rottenberg Y, Hamburger T, Mali B, Peretz T. Sonnenblick A, et al. Among authors: rottenberg y. Clin Transl Oncol. 2012 Mar;14(3):232-6. doi: 10.1007/s12094-012-0789-z. Clin Transl Oncol. 2012. PMID: 22374428
64 results