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High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue.
Zhang N, Harbers L, Simonetti M, Diekmann C, Verron Q, Berrino E, Bellomo SE, Longo GMC, Ratz M, Schultz N, Tarish F, Su P, Han B, Wang W, Onorato S, Grassini D, Ballarino R, Giordano S, Yang Q, Sapino A, Frisén J, Alkass K, Druid H, Roukos V, Helleday T, Marchiò C, Bienko M, Crosetto N. Zhang N, et al. Among authors: roukos v. Nat Commun. 2024 Apr 24;15(1):3475. doi: 10.1038/s41467-024-47664-z. Nat Commun. 2024. PMID: 38658552 Free PMC article.
PARP1 proximity proteomics reveals interaction partners at stressed replication forks.
Mosler T, Baymaz HI, Gräf JF, Mikicic I, Blattner G, Bartlett E, Ostermaier M, Piccinno R, Yang J, Voigt A, Gatti M, Pellegrino S, Altmeyer M, Luck K, Ahel I, Roukos V, Beli P. Mosler T, et al. Among authors: roukos v. Nucleic Acids Res. 2022 Nov 11;50(20):11600-11618. doi: 10.1093/nar/gkac948. Nucleic Acids Res. 2022. PMID: 36350633 Free PMC article.
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage.
Petropoulos M, Champeris Tsaniras S, Nikou S, Maxouri S, Dionellis VS, Kalogeropoulou A, Karamichali A, Ioannidis K, Danalatos IR, Obst M, Naumann R, Delinasios GJ, Gorgoulis VG, Roukos V, Anastassiadis K, Halazonetis TD, Bravou V, Lygerou Z, Taraviras S. Petropoulos M, et al. Among authors: roukos v. J Pathol. 2023 Jan;259(1):10-20. doi: 10.1002/path.6017. Epub 2022 Nov 9. J Pathol. 2023. PMID: 36210634
53BP1-mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling.
Tsaridou S, Velimezi G, Willenbrock F, Chatzifrangkeskou M, Elsayed W, Panagopoulos A, Karamitros D, Gorgoulis V, Lygerou Z, Roukos V, O'Neill E, Pefani DE. Tsaridou S, et al. Among authors: roukos v. EMBO Rep. 2022 Aug 3;23(8):e54483. doi: 10.15252/embr.202154483. Epub 2022 Jun 27. EMBO Rep. 2022. PMID: 35758159 Free PMC article.
RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1.
Abu-Libdeh B, Jhujh SS, Dhar S, Sommers JA, Datta A, Longo GM, Grange LJ, Reynolds JJ, Cooke SL, McNee GS, Hollingworth R, Woodward BL, Ganesh AN, Smerdon SJ, Nicolae CM, Durlacher-Betzer K, Molho-Pessach V, Abu-Libdeh A, Meiner V, Moldovan GL, Roukos V, Harel T, Brosh RM Jr, Stewart GS. Abu-Libdeh B, et al. Among authors: roukos v. J Clin Invest. 2022 Mar 1;132(5):e147301. doi: 10.1172/JCI147301. J Clin Invest. 2022. PMID: 35025765 Free PMC article.
Cohesin puts a break on distal homology hunt.
Papantonis A, Roukos V. Papantonis A, et al. Among authors: roukos v. Nat Cell Biol. 2021 Nov;23(11):1112-1114. doi: 10.1038/s41556-021-00791-x. Nat Cell Biol. 2021. PMID: 34750579 No abstract available.
RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis.
Zhang S, Übelmesser N, Josipovic N, Forte G, Slotman JA, Chiang M, Gothe HJ, Gusmao EG, Becker C, Altmüller J, Houtsmuller AB, Roukos V, Wendt KS, Marenduzzo D, Papantonis A. Zhang S, et al. Among authors: roukos v. Sci Adv. 2021 Oct 22;7(43):eabg8205. doi: 10.1126/sciadv.abg8205. Epub 2021 Oct 22. Sci Adv. 2021. PMID: 34678064 Free PMC article.
Territories or spaghetti? Chromosome organization exposed.
Longo GMC, Roukos V. Longo GMC, et al. Among authors: roukos v. Nat Rev Mol Cell Biol. 2021 Aug;22(8):508. doi: 10.1038/s41580-021-00372-8. Nat Rev Mol Cell Biol. 2021. PMID: 33854243 No abstract available.
35 results