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Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium.
Stern S, Santos R, Marchetto MC, Mendes APD, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH. Stern S, et al. Among authors: rouleau ga. Mol Psychiatry. 2018 Jun;23(6):1453-1465. doi: 10.1038/mp.2016.260. Epub 2017 Feb 28. Mol Psychiatry. 2018. PMID: 28242870 Free PMC article.
Evidence for a role of phospholipase C-gamma1 in the pathogenesis of bipolar disorder.
Turecki G, Grof P, Cavazzoni P, Duffy A, Grof E, Ahrens B, Berghöfer A, Müller-Oerlinghausen B, Dvoráková M, Libigerová E, Vojtechovský M, Zvolský P, Joober R, Nilsson A, Prochazka H, Licht RW, Rasmussen NA, Schou M, Vestergaard P, Holzinger A, Schumann C, Thau K, Rouleau GA, Alda M. Turecki G, et al. Among authors: rouleau ga. Mol Psychiatry. 1998 Nov;3(6):534-8. doi: 10.1038/sj.mp.4000447. Mol Psychiatry. 1998. PMID: 9857980
Association and linkage studies of candidate genes involved in GABAergic neurotransmission in lithium-responsive bipolar disorder.
Duffy A, Turecki G, Grof P, Cavazzoni P, Grof E, Joober R, Ahrens B, Berghöfer A, Müller-Oerlinghausen B, Dvoráková M, Libigerová E, Vojtĕchovský M, Zvolský P, Nilsson A, Licht RW, Rasmussen NA, Schou M, Vestergaard P, Holzinger A, Schumann C, Thau K, Robertson C, Rouleau GA, Alda M. Duffy A, et al. Among authors: rouleau ga. J Psychiatry Neurosci. 2000 Sep;25(4):353-8. J Psychiatry Neurosci. 2000. PMID: 11022400 Free PMC article.
Novel integrative genomic tool for interrogating lithium response in bipolar disorder.
Hunsberger JG, Chibane FL, Elkahloun AG, Henderson R, Singh R, Lawson J, Cruceanu C, Nagarajan V, Turecki G, Squassina A, Medeiros CD, Del Zompo M, Rouleau GA, Alda M, Chuang DM. Hunsberger JG, et al. Among authors: rouleau ga. Transl Psychiatry. 2015 Feb 3;5(2):e504. doi: 10.1038/tp.2014.139. Transl Psychiatry. 2015. PMID: 25646593 Free PMC article.
Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.
Cruceanu C, Schmouth JF, Torres-Platas SG, Lopez JP, Ambalavanan A, Darcq E, Gross F, Breton B, Spiegelman D, Rochefort D, Hince P, Petite JM, Gauthier J, Lafrenière RG, Dion PA, Greenwood CM, Kieffer BL, Alda M, Turecki G, Rouleau GA. Cruceanu C, et al. Among authors: rouleau ga. Mol Psychiatry. 2018 Oct;23(10):2050-2056. doi: 10.1038/mp.2017.223. Epub 2017 Nov 21. Mol Psychiatry. 2018. PMID: 29158579
805 results