Rowan AD - Search Results

1

Collagenase gene regulation by pro-inflammatory cytokines in cartilage.

Rowan AD, Young DA. Rowan AD, et al. Front Biosci. 2007 Jan 1;12:536-50. doi: 10.2741/2080. Front Biosci. 2007. PMID: 17127315 Review.

2

Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis.

Milner JM, Kevorkian L, Young DA, Jones D, Wait R, Donell ST, Barksby E, Patterson AM, Middleton J, Cravatt BF, Clark IM, Rowan AD, Cawston TE. Milner JM, et al. Among authors: rowan ad. Arthritis Res Ther. 2006;8(1):R23. doi: 10.1186/ar1877. Epub 2006 Jan 3. Arthritis Res Ther. 2006. PMID: 16507127 Free PMC article.

3

Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis.

Milner JM, Rowan AD, Cawston TE, Young DA. Milner JM, et al. Among authors: rowan ad. Arthritis Res Ther. 2006;8(5):R142. doi: 10.1186/ar2034. Arthritis Res Ther. 2006. PMID: 16919164 Free PMC article.

4

Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signaling-dependent.

Litherland GJ, Dixon C, Lakey RL, Robson T, Jones D, Young DA, Cawston TE, Rowan AD. Litherland GJ, et al. Among authors: rowan ad. J Biol Chem. 2008 May 23;283(21):14221-9. doi: 10.1074/jbc.M710136200. Epub 2008 Mar 10. J Biol Chem. 2008. PMID: 18332138 Free article.

5

Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis.

Milner JM, Patel A, Davidson RK, Swingler TE, Desilets A, Young DA, Kelso EB, Donell ST, Cawston TE, Clark IM, Ferrell WR, Plevin R, Lockhart JC, Leduc R, Rowan AD. Milner JM, et al. Among authors: rowan ad. Arthritis Rheum. 2010 Jul;62(7):1955-66. doi: 10.1002/art.27476. Arthritis Rheum. 2010. PMID: 20506309 Free article.

6

Lithium protects cartilage from cytokine-mediated degradation by reducing collagen-degrading MMP production via inhibition of the P38 mitogen-activated protein kinase pathway.

Hui W, Litherland GJ, Jefferson M, Barter MJ, Elias MS, Cawston TE, Rowan AD, Young DA. Hui W, et al. Among authors: rowan ad. Rheumatology (Oxford). 2010 Nov;49(11):2043-53. doi: 10.1093/rheumatology/keq217. Epub 2010 Jul 15. Rheumatology (Oxford). 2010. PMID: 20634235

7

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases.

Hui W, Litherland GJ, Elias MS, Kitson GI, Cawston TE, Rowan AD, Young DA. Hui W, et al. Among authors: rowan ad. Ann Rheum Dis. 2012 Mar;71(3):455-62. doi: 10.1136/annrheumdis-2011-200372. Epub 2011 Nov 9. Ann Rheum Dis. 2012. PMID: 22072016

8

Differential Toll-like receptor-dependent collagenase expression in chondrocytes.

Zhang Q, Hui W, Litherland GJ, Barter MJ, Davidson R, Darrah C, Donell ST, Clark IM, Cawston TE, Robinson JH, Rowan AD, Young DA. Zhang Q, et al. Among authors: rowan ad. Ann Rheum Dis. 2008 Nov;67(11):1633-41. doi: 10.1136/ard.2007.079574. Epub 2008 Feb 7. Ann Rheum Dis. 2008. PMID: 18258708

9

The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1.

Hall MC, Young DA, Waters JG, Rowan AD, Chantry A, Edwards DR, Clark IM. Hall MC, et al. Among authors: rowan ad. J Biol Chem. 2003 Mar 21;278(12):10304-13. doi: 10.1074/jbc.M212334200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525489 Free article.

10

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes.

Barter MJ, Pybus L, Litherland GJ, Rowan AD, Clark IM, Edwards DR, Cawston TE, Young DA. Barter MJ, et al. Among authors: rowan ad. Matrix Biol. 2010 Sep;29(7):602-12. doi: 10.1016/j.matbio.2010.05.002. Epub 2010 May 12. Matrix Biol. 2010. PMID: 20470885

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