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Year Number of Results
1988 1
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1990 1
1991 2
1993 1
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1999 1
2001 1
2002 5
2003 1
2004 1
2005 4
2006 2
2007 5
2008 6
2010 2
2011 4
2012 4
2013 5
2014 8
2015 7
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2017 15
2018 12
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214 results

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Page 1
RPS15 interacted with IGF2BP1 to promote esophageal squamous cell carcinoma development via recognizing m(6)A modification.
Zhao Y, Li Y, Zhu R, Feng R, Cui H, Yu X, Huang F, Zhang R, Chen X, Li L, Chen Y, Liu Y, Wang J, Du G, Liu Z. Zhao Y, et al. Signal Transduct Target Ther. 2023 Jun 2;8(1):224. doi: 10.1038/s41392-023-01428-1. Signal Transduct Target Ther. 2023. PMID: 37264021 Free PMC article.
Gain and loss of function models revealed that RPS15 promotes ESCC cell metastasis and proliferation, both in vitro and in vivo. ...Thus, RPS15 promotes ESCC progression via the p38 MAPK pathway and RPS15 inhibitors may serve as potential anti-ESCC drugs....
Gain and loss of function models revealed that RPS15 promotes ESCC cell metastasis and proliferation, both in vitro and in vivo. ...T …
RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia.
Ntoufa S, Gerousi M, Laidou S, Psomopoulos F, Tsiolas G, Moysiadis T, Papakonstantinou N, Mansouri L, Anagnostopoulos A, Stavrogianni N, Pospisilova S, Plevova K, Makris AM, Rosenquist R, Stamatopoulos K. Ntoufa S, et al. Blood Adv. 2021 Jul 13;5(13):2788-2792. doi: 10.1182/bloodadvances.2020001717. Blood Adv. 2021. PMID: 34251413 Free PMC article.
Recent studies of chronic lymphocytic leukemia (CLL) have reported recurrent mutations in the RPS15 gene, which encodes the ribosomal protein S15 (RPS15), a component of the 40S ribosomal subunit. Despite some evidence about the role of mutant RPS15 (mostly o …
Recent studies of chronic lymphocytic leukemia (CLL) have reported recurrent mutations in the RPS15 gene, which encodes the ribosomal …
Chronic lymphocytic leukemia (CLL)-Then and now.
Rai KR, Jain P. Rai KR, et al. Am J Hematol. 2016 Mar;91(3):330-40. doi: 10.1002/ajh.24282. Am J Hematol. 2016. PMID: 26690614 Free article. Review.
More recently, stereotypy of BCR (B cell receptor) and whole exome sequencing (WES) based discovery of specific mutations such as NOTCH1, TP53, SF3B1, XPO-1, BIRC3, ATM, and RPS15 further refined the current prognostication system in CLL. ...
More recently, stereotypy of BCR (B cell receptor) and whole exome sequencing (WES) based discovery of specific mutations such as NOTCH1, TP …
A transfer-RNA-derived small RNA regulates ribosome biogenesis.
Kim HK, Fuchs G, Wang S, Wei W, Zhang Y, Park H, Roy-Chaudhuri B, Li P, Xu J, Chu K, Zhang F, Chua MS, So S, Zhang QC, Sarnow P, Kay MA. Kim HK, et al. Nature. 2017 Dec 7;552(7683):57-62. doi: 10.1038/nature25005. Epub 2017 Nov 29. Nature. 2017. PMID: 29186115 Free PMC article.
This tsRNA binds at least two ribosomal protein mRNAs (RPS28 and RPS15) to enhance their translation. A decrease in translation of RPS28 mRNA blocks pre-18S ribosomal RNA processing, resulting in a reduction in the number of 40S ribosomal subunits. ...
This tsRNA binds at least two ribosomal protein mRNAs (RPS28 and RPS15) to enhance their translation. A decrease in translation of RP …
The value of RPS15 and MRPS27 in ischemic stroke.
Zhao M, Liu A, Mo L, Wan G, Lu F. Zhao M, et al. Medicine (Baltimore). 2023 Aug 18;102(33):e34706. doi: 10.1097/MD.0000000000034706. Medicine (Baltimore). 2023. PMID: 37603533 Free PMC article.
Comparative toxicogenomics database analysis showed that 6 genes (RPS15, RPS2, RPS3, MRPS27, POLR2A, MRPS26) were found to be associated with chemical and drug-induced liver injury, necrosis, delayed prenatal exposure, nephropathy, hepatomegaly and tumor. RPS15 and …
Comparative toxicogenomics database analysis showed that 6 genes (RPS15, RPS2, RPS3, MRPS27, POLR2A, MRPS26) were found to be associa …
The C-terminal tail of ribosomal protein Rps15 is engaged in cytoplasmic pre-40S maturation.
Rössler I, Weigl S, Fernández-Fernández J, Martín-Villanueva S, Strauss D, Hurt E, de la Cruz J, Pertschy B. Rössler I, et al. RNA Biol. 2022;19(1):560-574. doi: 10.1080/15476286.2022.2064073. Epub 2021 Dec 31. RNA Biol. 2022. PMID: 35438042 Free PMC article.
Here, we show that Rps15 not only functions in nucleolar ribosome assembly but also in cytoplasmic pre-40S maturation, which is indicated by a strong genetic interaction between Rps15 and the 40S assembly factor Ltv1. ...However, not only rps15 ltv1 double mu …
Here, we show that Rps15 not only functions in nucleolar ribosome assembly but also in cytoplasmic pre-40S maturation, which is indic …
mTORC1-Rps15 Axis Contributes to the Mechanisms Underlying Global Translation Reduction During Senescence of Mouse Embryonic Fibroblasts.
Wu S, Xu S, Li R, Li K, Zhong X, Li Y, Zhou Z, Liu Y, Feng R, Zheng J, Songyang Z, Liu F. Wu S, et al. Front Cell Dev Biol. 2019 Dec 11;7:337. doi: 10.3389/fcell.2019.00337. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31921849 Free PMC article.
Furthermore, RNA-seq analyses from polysomal versus total mRNA fractions identify TOP-like mRNA of Rps15 whose translation is regulated by mTORC1 during MEF senescence. Overexpression of Rps15 delays MEF senescence, possibly through regulating ribosome maturation. . …
Furthermore, RNA-seq analyses from polysomal versus total mRNA fractions identify TOP-like mRNA of Rps15 whose translation is regulat …
Mutations driving CLL and their evolution in progression and relapse.
Landau DA, Tausch E, Taylor-Weiner AN, Stewart C, Reiter JG, Bahlo J, Kluth S, Bozic I, Lawrence M, Böttcher S, Carter SL, Cibulskis K, Mertens D, Sougnez CL, Rosenberg M, Hess JM, Edelmann J, Kless S, Kneba M, Ritgen M, Fink A, Fischer K, Gabriel S, Lander ES, Nowak MA, Döhner H, Hallek M, Neuberg D, Getz G, Stilgenbauer S, Wu CJ. Landau DA, et al. Nature. 2015 Oct 22;526(7574):525-30. doi: 10.1038/nature15395. Epub 2015 Oct 14. Nature. 2015. PMID: 26466571 Free PMC article.
These include previously unrecognized putative cancer drivers (RPS15, IKZF3), and collectively identify RNA processing and export, MYC activity, and MAPK signalling as central pathways involved in CLL. ...
These include previously unrecognized putative cancer drivers (RPS15, IKZF3), and collectively identify RNA processing and export, MY …
Not so lost in translation: RPS15 mutations in CLL.
Ljungström V, Rosenquist R. Ljungström V, et al. Blood. 2018 Nov 29;132(22):2317-2319. doi: 10.1182/blood-2018-09-875179. Blood. 2018. PMID: 30498067 Free article. No abstract available.
214 results