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Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression.
Agudelo LZ, Femenía T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DMS, Krook A, Barres R, Zierath JR, Erhardt S, Lindskog M, Ruas JL. Agudelo LZ, et al. Among authors: ruas jl. Cell. 2014 Sep 25;159(1):33-45. doi: 10.1016/j.cell.2014.07.051. Cell. 2014. PMID: 25259918 Free article.
Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+ leak after one session of high-intensity interval exercise.
Place N, Ivarsson N, Venckunas T, Neyroud D, Brazaitis M, Cheng AJ, Ochala J, Kamandulis S, Girard S, Volungevičius G, Paužas H, Mekideche A, Kayser B, Martinez-Redondo V, Ruas JL, Bruton J, Truffert A, Lanner JT, Skurvydas A, Westerblad H. Place N, et al. Among authors: ruas jl. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15492-7. doi: 10.1073/pnas.1507176112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26575622 Free PMC article. Clinical Trial.
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.
Correia JC, Massart J, de Boer JF, Porsmyr-Palmertz M, Martínez-Redondo V, Agudelo LZ, Sinha I, Meierhofer D, Ribeiro V, Björnholm M, Sauer S, Dahlman-Wright K, Zierath JR, Groen AK, Ruas JL. Correia JC, et al. Among authors: ruas jl. Mol Metab. 2015 Sep 26;4(12):891-902. doi: 10.1016/j.molmet.2015.09.005. eCollection 2015 Dec. Mol Metab. 2015. PMID: 26909306 Free PMC article.
Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans.
Schlittler M, Goiny M, Agudelo LZ, Venckunas T, Brazaitis M, Skurvydas A, Kamandulis S, Ruas JL, Erhardt S, Westerblad H, Andersson DC. Schlittler M, et al. Among authors: ruas jl. Am J Physiol Cell Physiol. 2016 May 15;310(10):C836-40. doi: 10.1152/ajpcell.00053.2016. Epub 2016 Mar 30. Am J Physiol Cell Physiol. 2016. PMID: 27030575 Free article. Clinical Trial.
Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes.
Martínez-Redondo V, Jannig PR, Correia JC, Ferreira DM, Cervenka I, Lindvall JM, Sinha I, Izadi M, Pettersson-Klein AT, Agudelo LZ, Gimenez-Cassina A, Brum PC, Dahlman-Wright K, Ruas JL. Martínez-Redondo V, et al. Among authors: ruas jl. J Biol Chem. 2016 Jul 15;291(29):15169-84. doi: 10.1074/jbc.M115.705822. Epub 2016 May 26. J Biol Chem. 2016. PMID: 27231350 Free PMC article.
95 results