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208 results

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Challenges with Novel Clinical Trial Designs: Master Protocols.
Cecchini M, Rubin EH, Blumenthal GM, Ayalew K, Burris HA, Russell-Einhorn M, Dillon H, Lyerly HK, Reaman GH, Boerner S, LoRusso PM. Cecchini M, et al. Among authors: rubin eh. Clin Cancer Res. 2019 Apr 1;25(7):2049-2057. doi: 10.1158/1078-0432.CCR-18-3544. Epub 2019 Jan 29. Clin Cancer Res. 2019. PMID: 30696689
Advancing Clinical Trials to Streamline Drug Development.
Bates SE, Berry DA, Balasubramaniam S, Bailey S, LoRusso PM, Rubin EH. Bates SE, et al. Among authors: rubin eh. Clin Cancer Res. 2015 Oct 15;21(20):4527-35. doi: 10.1158/1078-0432.CCR-15-0039. Clin Cancer Res. 2015. PMID: 26473188 Free PMC article.
Improvements in quality of life and disease-related symptoms in phase I trials of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in non-small cell lung cancer and other solid tumors.
LoRusso PM, Herbst RS, Rischin D, Ranson M, Calvert H, Raymond E, Kieback D, Kaye S, Gianni L, Harris A, Bjork T, Maddox AM, Rothenberg ML, Small EJ, Rubin EH, Feyereislova A, Heyes A, Averbuch SD, Ochs J, Baselga J. LoRusso PM, et al. Among authors: rubin eh. Clin Cancer Res. 2003 Jun;9(6):2040-8. Clin Cancer Res. 2003. PMID: 12796366
Optimal two-stage designs for exploratory basket trials.
Zhou H, Liu F, Wu C, Rubin EH, Giranda VL, Chen C. Zhou H, et al. Among authors: rubin eh. Contemp Clin Trials. 2019 Oct;85:105807. doi: 10.1016/j.cct.2019.06.021. Epub 2019 Jun 29. Contemp Clin Trials. 2019. PMID: 31260789
Report on the Third FDA-AACR Oncology Dose-Finding Workshop.
Emens LA, Bruno R, Rubin EH, Jaffee EM, McKee AE. Emens LA, et al. Among authors: rubin eh. Cancer Immunol Res. 2017 Dec;5(12):1058-1061. doi: 10.1158/2326-6066.CIR-17-0590. Cancer Immunol Res. 2017. PMID: 29196440
Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial.
Herbst RS, Maddox AM, Rothenberg ML, Small EJ, Rubin EH, Baselga J, Rojo F, Hong WK, Swaisland H, Averbuch SD, Ochs J, LoRusso PM. Herbst RS, et al. Among authors: rubin eh. J Clin Oncol. 2002 Sep 15;20(18):3815-25. doi: 10.1200/JCO.2002.03.038. J Clin Oncol. 2002. PMID: 12228201 Clinical Trial.
208 results