Ruefli AA - Search Results

1

P-glycoprotein does not protect cells against cytolysis induced by pore-forming proteins.

Johnstone RW, Tainton KM, Ruefli AA, Froelich CJ, Cerruti L, Jane SM, Smyth MJ. Johnstone RW, et al. Among authors: ruefli aa. J Biol Chem. 2001 May 18;276(20):16667-73. doi: 10.1074/jbc.M010774200. Epub 2001 Feb 20. J Biol Chem. 2001. PMID: 11278745 Free article.

2

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells.

Ruefli AA, Bernhard D, Tainton KM, Kofler R, Smyth MJ, Johnstone RW. Ruefli AA, et al. Int J Cancer. 2002 May 10;99(2):292-8. doi: 10.1002/ijc.10327. Int J Cancer. 2002. PMID: 11979447 Free article.

3

Multiple physiological functions for multidrug transporter P-glycoprotein?

Johnstone RW, Ruefli AA, Smyth MJ. Johnstone RW, et al. Among authors: ruefli aa. Trends Biochem Sci. 2000 Jan;25(1):1-6. doi: 10.1016/s0968-0004(99)01493-0. Trends Biochem Sci. 2000. PMID: 10637601 Review.

4

HMBA induces activation of a caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistance.

Ruefli AA, Smyth MJ, Johnstone RW. Ruefli AA, et al. Blood. 2000 Apr 1;95(7):2378-85. Blood. 2000. PMID: 10733510 Free article.

5

A role for P-glycoprotein in regulating cell death.

Johnstone RW, Ruefli AA, Tainton KM, Smyth MJ. Johnstone RW, et al. Among authors: ruefli aa. Leuk Lymphoma. 2000 Jun;38(1-2):1-11. doi: 10.3109/10428190009060314. Leuk Lymphoma. 2000. PMID: 10811443 Review.

6

Equivalent death of P-glycoprotein expressing and nonexpressing cells induced by the protein kinase C inhibitor staurosporine.

Tainton KM, Ruefli AA, Smyth MJ, Johnstone RW. Tainton KM, et al. Among authors: ruefli aa. Biochem Biophys Res Commun. 2000 Sep 16;276(1):231-7. doi: 10.1006/bbrc.2000.3459. Biochem Biophys Res Commun. 2000. PMID: 11006111

7

P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation.

Ruefli AA, Tainton KM, Darcy PK, Smyth MJ, Johnstone RW. Ruefli AA, et al. Cell Death Differ. 2002 Nov;9(11):1266-72. doi: 10.1038/sj.cdd.4401081. Cell Death Differ. 2002. PMID: 12404126

8

Apoptosis: a link between cancer genetics and chemotherapy.

Johnstone RW, Ruefli AA, Lowe SW. Johnstone RW, et al. Among authors: ruefli aa. Cell. 2002 Jan 25;108(2):153-64. doi: 10.1016/s0092-8674(02)00625-6. Cell. 2002. PMID: 11832206 Free article. Review.

9

Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

Peart MJ, Tainton KM, Ruefli AA, Dear AE, Sedelies KA, O'Reilly LA, Waterhouse NJ, Trapani JA, Johnstone RW. Peart MJ, et al. Among authors: ruefli aa. Cancer Res. 2003 Aug 1;63(15):4460-71. Cancer Res. 2003. PMID: 12907619

10

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.

Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW. Ruefli AA, et al. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10833-8. doi: 10.1073/pnas.191208598. Epub 2001 Sep 4. Proc Natl Acad Sci U S A. 2001. PMID: 11535817 Free PMC article.

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