Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 3
1994 5
1995 14
1996 14
1997 5
1998 16
1999 9
2000 12
2001 8
2002 6
2003 6
2004 8
2005 6
2006 7
2007 15
2008 23
2009 29
2010 20
2011 26
2012 19
2013 25
2014 32
2015 23
2016 29
2017 35
2018 44
2019 50
2020 39
2021 56
2022 39
2023 52
2024 21

Text availability

Article attribute

Article type

Publication date

Search Results

620 results

Results by year

Filters applied: . Clear all
Page 1
RUNX1T1 function in cell fate.
Hu N, Zou L, Wang C, Song G. Hu N, et al. Stem Cell Res Ther. 2022 Jul 28;13(1):369. doi: 10.1186/s13287-022-03074-w. Stem Cell Res Ther. 2022. PMID: 35902872 Free PMC article. Review.
RUNX1T1 (Runt-related transcription factor 1, translocated to 1), a myeloid translocation gene (MTG) family member, is usually investigated as part of the fusion protein RUNX1-RUNX1T1 for its role in acute myeloid leukemia. ...Moreover, the formation of blood vessel …
RUNX1T1 (Runt-related transcription factor 1, translocated to 1), a myeloid translocation gene (MTG) family member, is usually invest …
An update on the molecular pathogenesis and potential therapeutic targeting of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1.
Al-Harbi S, Aljurf M, Mohty M, Almohareb F, Ahmed SOA. Al-Harbi S, et al. Blood Adv. 2020 Jan 14;4(1):229-238. doi: 10.1182/bloodadvances.2019000168. Blood Adv. 2020. PMID: 31935293 Free PMC article. Review.
Acute myeloid leukemia (AML) with t(8;21)(q22;q22.1);RUNX1-RUNX1T1, one of the core-binding factor leukemias, is one of the most common subtypes of AML with recurrent genetic abnormalities and is associated with a favorable outcome. The translocation leads to the formation …
Acute myeloid leukemia (AML) with t(8;21)(q22;q22.1);RUNX1-RUNX1T1, one of the core-binding factor leukemias, is one of the most comm …
The RUNX1/RUNX1T1 network: translating insights into therapeutic options.
Swart LE, Heidenreich O. Swart LE, et al. Exp Hematol. 2021 Feb;94:1-10. doi: 10.1016/j.exphem.2020.11.005. Epub 2020 Nov 17. Exp Hematol. 2021. PMID: 33217477 Free PMC article. Review.
RUNX1/RUNX1T1 is the most common fusion gene found in acute myeloid leukemia. ...Exploration of this transcriptional program by targeted RNAi screens uncovered a crucial role of RUNX1/RUNX1T1 in cell cycle progression by regulating CCND2. This dependency results in …
RUNX1/RUNX1T1 is the most common fusion gene found in acute myeloid leukemia. ...Exploration of this transcriptional program by targe …
Prospective evaluation of prognostic impact of KIT mutations on acute myeloid leukemia with RUNX1-RUNX1T1 and CBFB-MYH11.
Ishikawa Y, Kawashima N, Atsuta Y, Sugiura I, Sawa M, Dobashi N, Yokoyama H, Doki N, Tomita A, Kiguchi T, Koh S, Kanamori H, Iriyama N, Kohno A, Moriuchi Y, Asada N, Hirano D, Togitani K, Sakura T, Hagihara M, Tomikawa T, Yokoyama Y, Asou N, Ohtake S, Matsumura I, Miyazaki Y, Naoe T, Kiyoi H. Ishikawa Y, et al. Blood Adv. 2020 Jan 14;4(1):66-75. doi: 10.1182/bloodadvances.2019000709. Blood Adv. 2020. PMID: 31899799 Free PMC article.
Based on subgroup analysis, KIT mutations had a prognostic impact in patients with RUNX1-RUNX1T1, but not in those with CBFB-MYH11, and only exon 17 mutation had a significant prognostic impact. ...MRD was evaluated in 112 patients, and it was associated with a poorer RFS …
Based on subgroup analysis, KIT mutations had a prognostic impact in patients with RUNX1-RUNX1T1, but not in those with CBFB-MYH11, a …
Runx1t1 promotes the neuronal differentiation in rat hippocampus.
Zou L, Li H, Han X, Qin J, Song G. Zou L, et al. Stem Cell Res Ther. 2020 Apr 22;11(1):160. doi: 10.1186/s13287-020-01667-x. Stem Cell Res Ther. 2020. PMID: 32321587 Free PMC article.
RESULTS: Our results showed that insufficient expression of Runx1t1 reduced the neuronal differentiation, and overexpression of Runx1t1 promoted the neuronal differentiation in vitro. We also found that Runx1t1 localized in neurons but not astrocytes both in …
RESULTS: Our results showed that insufficient expression of Runx1t1 reduced the neuronal differentiation, and overexpression of Ru …
RUNX1T1, a potential prognostic marker in breast cancer, is co-ordinately expressed with ERalpha, and regulated by estrogen receptor signalling in breast cancer cells.
Saikia S, Pal U, Kalita DJ, Rai AK, Sarma A, Kataki AC, Limaye AM. Saikia S, et al. Mol Biol Rep. 2021 Jul;48(7):5399-5409. doi: 10.1007/s11033-021-06542-3. Epub 2021 Jul 15. Mol Biol Rep. 2021. PMID: 34264479
BACKGROUND: RUNX1T1 is extensively studied in the context of AML1-RUNX1T1 fusion protein in acute myeloid leukemia. ...Estrogen-ERalpha signalling downmodulates the expression of RUNX1T1 mRNA in ERalpha-positive breast cancer cells. In-depth investigations on …
BACKGROUND: RUNX1T1 is extensively studied in the context of AML1-RUNX1T1 fusion protein in acute myeloid leukemia. ...Estroge …
RUNX1T1 rs34269950 is associated with obesity and metabolic syndrome.
Zhou Y, Hambly BD, Simmons D, McLachlan CS. Zhou Y, et al. QJM. 2021 Nov 5;114(8):553-558. doi: 10.1093/qjmed/hcaa208. QJM. 2021. PMID: 32589708
BACKGROUND: Runt-related transcription factor 1 (RUNX1T1) isoforms are involved in adipogenesis. RUNX1T1 is mediated by the fat mass and obesity-associated (FTO). ...SNPs located in the coding region and 3'untranslated regions of RUNX1T1 with minor allele fre …
BACKGROUND: Runt-related transcription factor 1 (RUNX1T1) isoforms are involved in adipogenesis. RUNX1T1 is mediated by the fa …
Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells.
Kumar P, Verma V, Mohania D, Gupta S, Babbar AK, Rathi B, Dhanda RS, Yadav M. Kumar P, et al. J Cell Biochem. 2021 Nov;122(11):1737-1748. doi: 10.1002/jcb.30126. Epub 2021 Aug 9. J Cell Biochem. 2021. PMID: 34369622
RUNX1T1 has been found to be mutated in different cancers such as prostate, lung, colon, and breast cancer. ...We have evaluated the expression level of RUNX1T1 at different stages of glioma and the effect of RUNX1T1 on the proliferation and invasiveness of g …
RUNX1T1 has been found to be mutated in different cancers such as prostate, lung, colon, and breast cancer. ...We have evaluated the …
RUNX1T1 modulates myogenic differentiation by regulating the calcium signaling pathway and the alternative splicing of ROCK2.
Deng K, Liu Z, Su Y, Zhang Z, Fan Y, Zhang Y, Wang F. Deng K, et al. FASEB J. 2023 Jul;37(7):e23044. doi: 10.1096/fj.202300677R. FASEB J. 2023. PMID: 37342905
However, little is known about the function of RUNX1T1 in the skeletal muscle development. Here, we assessed the impact of RUNX1T1 on the proliferation and myogenic differentiation of goat primary myoblasts (GPMs). ...Additionally, we discovered that RUNX1T1 …
However, little is known about the function of RUNX1T1 in the skeletal muscle development. Here, we assessed the impact of RUNX1T1 …
620 results