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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 1
1953 1
1957 1
1960 2
1965 1
1968 1
1973 1
1974 2
1975 1
1976 2
1977 1
1979 1
1980 1
1983 2
1984 1
1985 2
1987 1
1988 2
1989 2
1990 1
1991 2
1992 2
1993 3
1994 2
1995 2
1996 2
1997 1
1998 4
1999 5
2000 5
2001 5
2002 4
2003 3
2004 1
2005 3
2006 5
2007 5
2008 5
2009 5
2010 2
2011 3
2012 6
2013 4
2014 2
2015 4
2016 6
2017 5
2018 6
2019 6
2020 3
2021 6
2022 4
2023 3
2024 1

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145 results

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Page 1
Ruscus Genus: A Rich Source of Bioactive Steroidal Saponins.
Masullo M, Pizza C, Piacente S. Masullo M, et al. Planta Med. 2016 Dec;82(18):1513-1524. doi: 10.1055/s-0042-119728. Epub 2016 Nov 8. Planta Med. 2016. PMID: 27825178 Review.
The genus Ruscus (Asparagaceae family) is native to the Mediterranean, Southern and Western Europe and is represented by perennial, rhizomatous, and evergreen shrubs. ...This review provides an overview of the traditional use of Ruscus spp., the current knowledge of …
The genus Ruscus (Asparagaceae family) is native to the Mediterranean, Southern and Western Europe and is represented by perennial, r …
Efficacy of Ruscus extract, HMC and vitamin C, constituents of Cyclo 3 fort, on improving individual venous symptoms and edema: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials.
Kakkos SK, Allaert FA. Kakkos SK, et al. Int Angiol. 2017 Apr;36(2):93-106. doi: 10.23736/S0392-9590.17.03815-9. Int Angiol. 2017. PMID: 28225220 Free article. Review.
The aim of the present systematic review and meta-analysis was to study the effectiveness of VADs containing Ruscus across the spectrum of defined venous symptoms. EVIDENCE ACQUISITION: On November 14 2016, a literature search of the databases MEDLINE and Scopus was perfor …
The aim of the present systematic review and meta-analysis was to study the effectiveness of VADs containing Ruscus across the spectr …
The place of Ruscus extract, hesperidin methyl chalcone, and vitamin C in the management of chronic venous disease.
Jawien A, Bouskela E, Allaert FA, Nicolaïdes AN. Jawien A, et al. Int Angiol. 2017 Feb;36(1):31-41. doi: 10.23736/S0392-9590.16.03788-3. Int Angiol. 2017. PMID: 28124877 Free article. Review.
Despite continuous improvement in our knowledge and management of chronic venous disease (CVD), certain areas, such as the role of muscarinic receptors in the pathology and treatment of CVD, remain unexplored. The symposium "The place of Ruscus extract, hesperidin methyl c …
Despite continuous improvement in our knowledge and management of chronic venous disease (CVD), certain areas, such as the role of muscarini …
Clinical Perspectives and Management of Edema in Chronic Venous Disease-What about Ruscus?
Bihari I, Guex JJ, Jawien A, Szolnoky G. Bihari I, et al. Medicines (Basel). 2022 Jul 25;9(8):41. doi: 10.3390/medicines9080041. Medicines (Basel). 2022. PMID: 35893088 Free PMC article. Review.
The recent CEAP classification update states that edema should be considered a sign of CVD. The combination of Ruscus extract, hesperidin methyl chalcone and vitamin C improves venous tone and lymph contractility and reduces macromolecule permeability and inflammation. Con …
The recent CEAP classification update states that edema should be considered a sign of CVD. The combination of Ruscus extract, hesper …
Combination of Ruscus aculeatus extract, hesperidin methyl chalcone and ascorbic acid: a comprehensive review of their pharmacological and clinical effects and of the pathophysiology of chronic venous disease.
Allaert FA. Allaert FA. Int Angiol. 2016 Apr;35(2):111-6. Int Angiol. 2016. PMID: 26928296 Review.
This paper focuses on Ruscus aculeatus extract (Ruscus extract) and its combination with hesperidin methyl chalcone (HMC) and ascorbic acid (AA), which have been safely and effectively used in CVD treatment for more than 50 years in some European countries. ...
This paper focuses on Ruscus aculeatus extract (Ruscus extract) and its combination with hesperidin methyl chalcone (HMC) and …
Peripheral Edema: Evaluation and Management in Primary Care.
Patel H, Skok C, DeMarco A. Patel H, et al. Am Fam Physician. 2022 Nov;106(5):557-564. Am Fam Physician. 2022. PMID: 36379502
Diuretics are effective but should be used only for systemic causes of edema. Ruscus extract and horse chestnut seed demonstrate moderate-quality evidence to improve edema from chronic venous insufficiency. ...
Diuretics are effective but should be used only for systemic causes of edema. Ruscus extract and horse chestnut seed demonstrate mode …
Lymphotonic activity of Ruscus extract, hesperidin methyl chalcone and vitamin C in human lymphatic smooth muscle cells.
Monjotin N, Tenca G. Monjotin N, et al. Microvasc Res. 2022 Jan;139:104274. doi: 10.1016/j.mvr.2021.104274. Epub 2021 Oct 27. Microvasc Res. 2022. PMID: 34717967 Free article.
The objective of this study was to evaluate the effect of the combination of Ruscus, hesperidin methyl chalcone and Vitamin C (Ruscus/HMC/Vit C) on intracellular calcium mobilization and contraction of human lymphatic smooth muscle cells (LSMCs) to better characteri …
The objective of this study was to evaluate the effect of the combination of Ruscus, hesperidin methyl chalcone and Vitamin C (Rus …
A Literature Review of Pharmacological Agents to Improve Venous Leg Ulcer Healing.
Kitchens BP, Snyder RJ, Cuffy CA. Kitchens BP, et al. Wounds. 2020 Jul;32(7):195-207. Wounds. 2020. PMID: 33166265 Free article. Review.
The following available venotonic, hemorheologic, and fibrinolytic agents were reviewed for oral management in treating VLUs: pentoxifylline, flavonoids (diosmin, hidrosmin, rutosides, and micronized purified flavonoid fraction, Vasculera), Red-Vine-Leaf-Extract AS 195, Ruscus …
The following available venotonic, hemorheologic, and fibrinolytic agents were reviewed for oral management in treating VLUs: pentoxifylline …
Effects of Ruscus extract on muscarinic receptors: Is there a role for endothelium derived relaxing factors on macromolecular permeability protection and microvascular diameter changes?
de Souza MDGC, Cyrino FZGA, Sicuro FL, Bouskela E. de Souza MDGC, et al. Clin Hemorheol Microcirc. 2021;77(4):443-459. doi: 10.3233/CH-201019. Clin Hemorheol Microcirc. 2021. PMID: 33459701
RESULTS: Ruscus extract decreased macromolecular permeability in a dose-dependent fashion and did not affect microvascular diameters. ...NOS inhibition reduced arteriolar diameter and COX blocking decreased arteriolar and venular diameters at the lowest dose and increased …
RESULTS: Ruscus extract decreased macromolecular permeability in a dose-dependent fashion and did not affect microvascular diameters. …
145 results