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Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H Jr, Kneitz B, Lagaud G, Christ GJ, Edelmann W, Lisanti MP. Razani B, et al. Among authors: russell rg. J Biol Chem. 2001 Oct 12;276(41):38121-38. doi: 10.1074/jbc.M105408200. Epub 2001 Jul 16. J Biol Chem. 2001. PMID: 11457855 Free article.
p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Hulit J, Lee RJ, Li Z, Wang C, Katiyar S, Yang J, Quong AA, Wu K, Albanese C, Russell R, Di Vizio D, Koff A, Thummala S, Zhang H, Harrell J, Sun H, Muller WJ, Inghirami G, Lisanti MP, Pestell RG. Hulit J, et al. Among authors: russell r. Cancer Res. 2006 Sep 1;66(17):8529-41. doi: 10.1158/0008-5472.CAN-06-0149. Cancer Res. 2006. PMID: 16951165
Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts.
Cohen AW, Park DS, Woodman SE, Williams TM, Chandra M, Shirani J, Pereira de Souza A, Kitsis RN, Russell RG, Weiss LM, Tang B, Jelicks LA, Factor SM, Shtutin V, Tanowitz HB, Lisanti MP. Cohen AW, et al. Among authors: russell rg. Am J Physiol Cell Physiol. 2003 Feb;284(2):C457-74. doi: 10.1152/ajpcell.00380.2002. Epub 2002 Oct 9. Am J Physiol Cell Physiol. 2003. PMID: 12388077 Free article.
Urogenital alterations in aged male caveolin-1 knockout mice.
Woodman SE, Cheung MW, Tarr M, North AC, Schubert W, Lagaud G, Marks CB, Russell RG, Hassan GS, Factor SM, Christ GJ, Lisanti MP. Woodman SE, et al. Among authors: russell rg. J Urol. 2004 Feb;171(2 Pt 1):950-7. doi: 10.1097/01.ju.0000105102.72295.b8. J Urol. 2004. PMID: 14713860
Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment.
Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, Lee H, Temple K, Graves R, Pollard J, Chopra N, Russell RG, Sasisekharan R, Trock BJ, Lippman M, Calvert VS, Petricoin EF 3rd, Liotta L, Dadachova E, Pestell RG, Lisanti MP, Bonaldo P, Scherer PE. Iyengar P, et al. Among authors: russell rg. J Clin Invest. 2005 May;115(5):1163-76. doi: 10.1172/JCI23424. Epub 2005 Apr 14. J Clin Invest. 2005. PMID: 15841211 Free PMC article.
Akt1 governs breast cancer progression in vivo.
Ju X, Katiyar S, Wang C, Liu M, Jiao X, Li S, Zhou J, Turner J, Lisanti MP, Russell RG, Mueller SC, Ojeifo J, Chen WS, Hay N, Pestell RG. Ju X, et al. Among authors: russell rg. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7438-43. doi: 10.1073/pnas.0605874104. Epub 2007 Apr 25. Proc Natl Acad Sci U S A. 2007. PMID: 17460049 Free PMC article.
501 results