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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, Chen Y, Morrow E, Weir EK, Rehman J, Archer SL. Marsboom G, et al. Among authors: ryan jj. Circ Res. 2012 May 25;110(11):1484-97. doi: 10.1161/CIRCRESAHA.111.263848. Epub 2012 Apr 17. Circ Res. 2012. PMID: 22511751 Free PMC article.
GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.
Piao L, Fang YH, Parikh KS, Ryan JJ, D'Souza KM, Theccanat T, Toth PT, Pogoriler J, Paul J, Blaxall BC, Akhter SA, Archer SL. Piao L, et al. Among authors: ryan jj. Circulation. 2012 Dec 11;126(24):2859-69. doi: 10.1161/CIRCULATIONAHA.112.109868. Epub 2012 Nov 2. Circulation. 2012. PMID: 23124027 Free PMC article.
Rodent models of group 1 pulmonary hypertension.
Ryan JJ, Marsboom G, Archer SL. Ryan JJ, et al. Handb Exp Pharmacol. 2013;218:105-49. doi: 10.1007/978-3-642-38664-0_5. Handb Exp Pharmacol. 2013. PMID: 24092338 Review.
625 results