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REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment.
ACS Cent Sci. 2018 Jan 24;4(1):89-96. doi: 10.1021/acscentsci.7b00475. Epub 2018 Jan 2.
ACS Cent Sci. 2018.
PMID: 29392180
Free PMC article.
Molecular dynamics simulations reveal ligand-controlled positioning of a peripheral protein complex in membranes.
Ryckbosch SM, Wender PA, Pande VS.
Ryckbosch SM, et al.
Nat Commun. 2017 Feb 23;8(1):6. doi: 10.1038/s41467-016-0015-8.
Nat Commun. 2017.
PMID: 28232750
Free PMC article.
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In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
Marsden MD, Loy BA, Wu X, Ramirez CM, Schrier AJ, Murray D, Shimizu A, Ryckbosch SM, Near KE, Chun TW, Wender PA, Zack JA.
Marsden MD, et al. Among authors: ryckbosch sm.
PLoS Pathog. 2017 Sep 21;13(9):e1006575. doi: 10.1371/journal.ppat.1006575. eCollection 2017 Sep.
PLoS Pathog. 2017.
PMID: 28934369
Free PMC article.
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Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV.
Wender PA, Hardman CT, Ho S, Jeffreys MS, Maclaren JK, Quiroz RV, Ryckbosch SM, Shimizu AJ, Sloane JL, Stevens MC.
Wender PA, et al. Among authors: ryckbosch sm.
Science. 2017 Oct 13;358(6360):218-223. doi: 10.1126/science.aan7969.
Science. 2017.
PMID: 29026042
Free PMC article.
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Function-Oriented Synthesis: Design, Synthesis, and Evaluation of Highly Simplified Bryostatin Analogues.
Wender PA, Sloane JL, Luu-Nguyen QH, Ogawa Y, Shimizu AJ, Ryckbosch SM, Tyler JH, Hardman C.
Wender PA, et al. Among authors: ryckbosch sm.
J Org Chem. 2020 Dec 4;85(23):15116-15128. doi: 10.1021/acs.joc.0c01988. Epub 2020 Nov 17.
J Org Chem. 2020.
PMID: 33200928
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