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Page 1
Diels-Alder reactions of cyclic isoimidium salts.
Boeckman RK Jr, Miller Y, Ryder TR. Boeckman RK Jr, et al. Among authors: ryder tr. Org Lett. 2010 Oct 15;12(20):4524-7. doi: 10.1021/ol101831b. Org Lett. 2010. PMID: 20843021
A Scalable Total Synthesis of (-)-Nakadomarin A.
Boeckman RK Jr, Wang H, Rugg KW, Genung NE, Chen K, Ryder TR. Boeckman RK Jr, et al. Among authors: ryder tr. Org Lett. 2016 Dec 2;18(23):6136-6139. doi: 10.1021/acs.orglett.6b03137. Epub 2016 Nov 11. Org Lett. 2016. PMID: 27934385
Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction.
Golebiowski A, Whitehouse D, Beckett RP, Van Zandt M, Ji MK, Ryder TR, Jagdmann E, Andreoli M, Lee Y, Sheeler R, Conway B, Olczak J, Mazur M, Czestkowski W, Piotrowska W, Cousido-Siah A, Ruiz FX, Mitschler A, Podjarny A, Schroeter H. Golebiowski A, et al. Among authors: ryder tr. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4837-41. doi: 10.1016/j.bmcl.2013.06.092. Epub 2013 Jul 8. Bioorg Med Chem Lett. 2013. PMID: 23886684
2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors.
Golebiowski A, Paul Beckett R, Van Zandt M, Ji MK, Whitehouse D, Ryder TR, Jagdmann E, Andreoli M, Mazur A, Padmanilayam M, Cousido-Siah A, Mitschler A, Ruiz FX, Podjarny A, Schroeter H. Golebiowski A, et al. Among authors: ryder tr. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2027-30. doi: 10.1016/j.bmcl.2013.02.024. Epub 2013 Feb 13. Bioorg Med Chem Lett. 2013. PMID: 23453840
Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury.
Van Zandt MC, Whitehouse DL, Golebiowski A, Ji MK, Zhang M, Beckett RP, Jagdmann GE, Ryder TR, Sheeler R, Andreoli M, Conway B, Mahboubi K, D'Angelo G, Mitschler A, Cousido-Siah A, Ruiz FX, Howard EI, Podjarny AD, Schroeter H. Van Zandt MC, et al. Among authors: ryder tr. J Med Chem. 2013 Mar 28;56(6):2568-80. doi: 10.1021/jm400014c. Epub 2013 Mar 8. J Med Chem. 2013. PMID: 23472952
The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Hu LY, Boxer PA, Kesten SR, Lei HJ, Wustrow DJ, Moreland DW, Zhang L, Ahn K, Ryder TR, Liu X, Rubin JR, Fahnoe K, Carroll RT, Dutta S, Fahnoe DC, Probert AW, Roof RL, Rafferty MF, Kostlan CR, Scholten JD, Hood M, Ren XD, Schielke GP, Su TZ, Taylor CP, Mistry A, McConnell P, Hasemann C, Ohren J. Hu LY, et al. Among authors: ryder tr. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. doi: 10.1016/j.bmcl.2005.07.058. Epub 2005 Sep 6. Bioorg Med Chem Lett. 2006. PMID: 16143519
17 results