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The in vitro and in vivo efficacy of CT-P59 against Gamma, Delta and its associated variants of SARS-CoV-2.
Ryu DK, Kang B, Noh H, Woo SJ, Lee MH, Nuijten PM, Kim JI, Seo JM, Kim C, Kim M, Yang E, Lim G, Kim SG, Eo SK, Choi JA, Song M, Oh SS, Chung HY, Tijsma AS, van Baalen CA, Kwon KS, Lee SY. Ryu DK, et al. Biochem Biophys Res Commun. 2021 Nov 12;578:91-96. doi: 10.1016/j.bbrc.2021.09.023. Epub 2021 Sep 13. Biochem Biophys Res Commun. 2021. PMID: 34547629 Free PMC article.
A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein.
Kim C, Ryu DK, Lee J, Kim YI, Seo JM, Kim YG, Jeong JH, Kim M, Kim JI, Kim P, Bae JS, Shim EY, Lee MS, Kim MS, Noh H, Park GS, Park JS, Son D, An Y, Lee JN, Kwon KS, Lee JY, Lee H, Yang JS, Kim KC, Kim SS, Woo HM, Kim JW, Park MS, Yu KM, Kim SM, Kim EH, Park SJ, Jeong ST, Yu CH, Song Y, Gu SH, Oh H, Koo BS, Hong JJ, Ryu CM, Park WB, Oh MD, Choi YK, Lee SY. Kim C, et al. Among authors: ryu dk. Nat Commun. 2021 Jan 12;12(1):288. doi: 10.1038/s41467-020-20602-5. Nat Commun. 2021. PMID: 33436577 Free PMC article.
Preclinical assessment and randomized Phase I study of CT-P63, a broadly neutralizing antibody targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Seo JM, Kang B, Song R, Noh H, Kim C, Kim JI, Kim M, Ryu DK, Lee MH, Yang JS, Kim KC, Lee JY, Lee H, Woo HM, Kim JW, Choi JA, Song M, Tomaszewska-Kiecana M, Wołowik A, Kulesza A, Kim S, Ahn K, Jung N, Lee SY. Seo JM, et al. Among authors: ryu dk. Emerg Microbes Infect. 2022 Dec;11(1):2315-2325. doi: 10.1080/22221751.2022.2117094. Emerg Microbes Infect. 2022. PMID: 36006772 Free PMC article. Clinical Trial.
Therapeutic effect of CT-P59 against SARS-CoV-2 South African variant.
Ryu DK, Song R, Kim M, Kim YI, Kim C, Kim JI, Kwon KS, Tijsma AS, Nuijten PM, van Baalen CA, Hermanus T, Kgagudi P, Moyo-Gwete T, Moore PL, Choi YK, Lee SY. Ryu DK, et al. Biochem Biophys Res Commun. 2021 Aug 20;566:135-140. doi: 10.1016/j.bbrc.2021.06.016. Epub 2021 Jun 7. Biochem Biophys Res Commun. 2021. PMID: 34119826 Free PMC article.
25 results