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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 1
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2010 2
2012 1
2014 2
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2023 1
2024 0

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18 results

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Page 1
Long noncoding RNA HOXA-AS2 regulates the expression of SCN3A by sponging miR-106a in breast cancer.
Wu J, Li M, Zhang Y. Wu J, et al. J Cell Biochem. 2019 Sep;120(9):14465-14475. doi: 10.1002/jcb.28706. Epub 2019 Apr 16. J Cell Biochem. 2019. PMID: 30993766
Breast cancer is the most commonly diagnosed cancer that affects women worldwide. ...The results showed that lncRNA HOXA-AS2 might modulate the expression of SCN3A by sponging miR-106a in breast cancer....
Breast cancer is the most commonly diagnosed cancer that affects women worldwide. ...The results showed that lncRNA HOXA-AS2 m …
SCN3A-Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation.
Zaman T, Helbig KL, Clatot J, Thompson CH, Kang SK, Stouffs K, Jansen AE, Verstraete L, Jacquinet A, Parrini E, Guerrini R, Fujiwara Y, Miyatake S, Ben-Zeev B, Bassan H, Reish O, Marom D, Hauser N, Vu TA, Ackermann S, Spencer CE, Lippa N, Srinivasan S, Charzewska A, Hoffman-Zacharska D, Fitzpatrick D, Harrison V, Vasudevan P, Joss S, Pilz DT, Fawcett KA, Helbig I, Matsumoto N, Kearney JA, Fry AE, Goldberg EM. Zaman T, et al. Ann Neurol. 2020 Aug;88(2):348-362. doi: 10.1002/ana.25809. Epub 2020 Jul 9. Ann Neurol. 2020. PMID: 32515017 Free PMC article.
OBJECTIVE: Pathogenic variants in SCN3A, encoding the voltage-gated sodium channel subunit Nav1.3, cause severe childhood onset epilepsy and malformation of cortical development. Here, we define the spectrum of clinical, genetic, and neuroimaging features of SCN3A-r …
OBJECTIVE: Pathogenic variants in SCN3A, encoding the voltage-gated sodium channel subunit Nav1.3, cause severe childhood onset epile …
Identification of Key Circulating Exosomal microRNAs in Gastric Cancer.
Qian X, Xie F, Wei H, Cui D. Qian X, et al. Front Oncol. 2021 Jul 16;11:693360. doi: 10.3389/fonc.2021.693360. eCollection 2021. Front Oncol. 2021. PMID: 34336682 Free PMC article.
Exosomal miRNAs (EmiRs) can be used for prediction of gastric cancer (GC) development. Supposedly, both plasma and urinary microRNAs can also be potential biomarkers for screening, but the diagnostic values of EmiRs in blood and urine are not fully studied. ...The PPI netw …
Exosomal miRNAs (EmiRs) can be used for prediction of gastric cancer (GC) development. Supposedly, both plasma and urinary microRNAs …
Voltage Gated Sodium Channel Genes in Epilepsy: Mutations, Functional Studies, and Treatment Dimensions.
Ademuwagun IA, Rotimi SO, Syrbe S, Ajamma YU, Adebiyi E. Ademuwagun IA, et al. Front Neurol. 2021 Mar 24;12:600050. doi: 10.3389/fneur.2021.600050. eCollection 2021. Front Neurol. 2021. PMID: 33841294 Free PMC article. Review.
A noteworthy class of ion channel genes are the voltage gated sodium channels (VGSCs) that play key roles in the depolarization phase of action potentials in neurons. Of huge significance are SCN1A, SCN1B, SCN2A, SCN3A, and SCN8A genes that are highly expressed in the brai …
A noteworthy class of ion channel genes are the voltage gated sodium channels (VGSCs) that play key roles in the depolarization phase of act …
The Yin and Yang of Breast Cancer: Ion Channels as Determinants of Left-Right Functional Differences.
Masuelli S, Real S, McMillen P, Oudin M, Levin M, Roqué M. Masuelli S, et al. Int J Mol Sci. 2023 Jul 5;24(13):11121. doi: 10.3390/ijms241311121. Int J Mol Sci. 2023. PMID: 37446299 Free PMC article.
Breast cancer is a complex and heterogeneous disease that displays diverse molecular subtypes and clinical outcomes. ...We identified a 6-ion channel-gene signature (CACNA1C, CACNA2D2, CACNB2, KCNJ11, SCN3A, and SCN3B) associated with the side: L-tumors exhibit lowe …
Breast cancer is a complex and heterogeneous disease that displays diverse molecular subtypes and clinical outcomes. ...We identified …
Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.
Hessel EV, van Lith HA, Wolterink-Donselaar IG, de Wit M, Groot Koerkamp MJ, Holstege FC, Kas MJ, Fernandes C, de Graan PN. Hessel EV, et al. Eur J Neurosci. 2016 Dec;44(11):2950-2957. doi: 10.1111/ejn.13420. Eur J Neurosci. 2016. PMID: 27690330
Four of these (Arl6ip6, Cytip, Fmnl2 Ifih1) contained a non-synonymous SNP comparing CSS2 and C57BL/6J, six genes (March7, Nr4a2, Gpd2, Grb14, Scn1a, Scn3a) were differentially expressed between these strains. A region within FS-QTL2a is homologous to the human FEB3 locus. …
Four of these (Arl6ip6, Cytip, Fmnl2 Ifih1) contained a non-synonymous SNP comparing CSS2 and C57BL/6J, six genes (March7, Nr4a2, Gpd2, Grb1 …
Expression of voltage-gated sodium channel alpha subunit in human ovarian cancer.
Gao R, Shen Y, Cai J, Lei M, Wang Z. Gao R, et al. Oncol Rep. 2010 May;23(5):1293-9. doi: 10.3892/or_00000763. Oncol Rep. 2010. PMID: 20372843
Voltage-gated sodium channels (VGSC) play important roles in the development and progression of many cancers. We report the possible roles of VGSC in human ovarian cancer. Relative mRNA expression levels of Nav1.1, Nav1.3, Nav1.4 and Nav1.5, analyzed by RT-PCR, were …
Voltage-gated sodium channels (VGSC) play important roles in the development and progression of many cancers. We report the possible …
Identification of Key Genes Associated with Risk and Prognosis of Neuroblastoma.
Zhang J, Han Y, Yan D, Zhou D, Yuan X, Zhao W, Zhang D. Zhang J, et al. J Mol Neurosci. 2022 Dec;72(12):2398-2412. doi: 10.1007/s12031-022-02087-7. Epub 2022 Nov 29. J Mol Neurosci. 2022. PMID: 36443552
Finally, we evaluated the difference in DNA methylation levels to identify meaningful methylation marks. We identified 5 key genes (ANO6, CPNE2, DST, PLXNC1, SCN3A) for neuroblastoma risk and prognosis, which correlated closely with known neuroblastoma biomarkers. ...
Finally, we evaluated the difference in DNA methylation levels to identify meaningful methylation marks. We identified 5 key genes (ANO6, CP …
Upregulated genes at 2q24 gains as candidate oncogenes in hepatoblastomas.
Rodrigues TC, Fidalgo F, da Costa CM, Ferreira EN, da Cunha IW, Carraro DM, Krepischi AC, Rosenberg C. Rodrigues TC, et al. Future Oncol. 2014 Dec;10(15):2449-57. doi: 10.2217/fon.14.149. Future Oncol. 2014. PMID: 25525853
Expression analysis of 48 genes mapped at one 10 Mb amplification at 2q24 revealed upregulation of DAPL1, ERMN, GALNT5, SCN1A and SCN3A in the set of tumors compared with differentiated livers. CONCLUSION: These genes appear as candidates for hepatoblastoma tumorigenesis.. …
Expression analysis of 48 genes mapped at one 10 Mb amplification at 2q24 revealed upregulation of DAPL1, ERMN, GALNT5, SCN1A and SCN3A …
Insight into the potential candidate genes and signaling pathways involved in lymphoma disease in dogs using a comprehensive whole blood transcriptome analysis.
Sheet S, Oh YI, Arora D, Choi BH, Ko M, Nam Y, Lim Y, Lim JA, Park M, Park W, Seo KW, Lee KT. Sheet S, et al. Gene. 2022 Sep 5;838:146735. doi: 10.1016/j.gene.2022.146735. Epub 2022 Jul 12. Gene. 2022. PMID: 35835403
Lymphoma is one of the most prevalent hematological cancers, accounting for 15-20 % of new cancer diagnoses in dogs. Therefore, this study aims to explore the important genes and pathways involved in canine lymphoma progression and understand the underlying molecula …
Lymphoma is one of the most prevalent hematological cancers, accounting for 15-20 % of new cancer diagnoses in dogs. Therefore …
18 results