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Year Number of Results
1986 1
1988 1
1993 1
1995 1
1996 7
1997 16
1998 52
1999 67
2000 92
2001 105
2002 102
2003 119
2004 130
2005 166
2006 192
2007 224
2008 212
2009 224
2010 264
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2012 271
2013 248
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2020 193
2021 38
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3,934 results
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Exosomes derived from SDF1-overexpressing mesenchymal stem cells inhibit ischemic myocardial cell apoptosis and promote cardiac endothelial microvascular regeneration in mice with myocardial infarction.
Gong XH, Liu H, Wang SJ, Liang SW, Wang GG. Gong XH, et al. J Cell Physiol. 2019 Aug;234(8):13878-13893. doi: 10.1002/jcp.28070. Epub 2019 Feb 5. J Cell Physiol. 2019. PMID: 30720220
During the coculture experiments, exosome secretion was disrupted by neutral sphingomyelinase inhibitor GW4869 and upregulated exosomal SDF1 using SDF1 plasmid. Effects of Exo-SDF1 on cardiac function in MI mice were investigated in vivo. ...The interference …
During the coculture experiments, exosome secretion was disrupted by neutral sphingomyelinase inhibitor GW4869 and upregulated exosomal S
Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.
Nishiguchi MA, Spencer CA, Leung DH, Leung TH. Nishiguchi MA, et al. Cell Rep. 2018 Sep 25;24(13):3383-3392.e5. doi: 10.1016/j.celrep.2018.08.054. Cell Rep. 2018. PMID: 30257200 Free PMC article.
Exposure of aged animals to blood from young mice by parabiosis counteracts this regenerative capacity. The secreted factor, stromal-derived factor 1 (SDF1), is expressed at higher levels in wounded skin of young mice. Genetic deletion of SDF1 in young skin enhanced …
Exposure of aged animals to blood from young mice by parabiosis counteracts this regenerative capacity. The secreted factor, stromal-derived …
Role of the CXCR4-SDF1-HMGB1 pathway in the directional migration of cells and regeneration of affected organs.
Haque N, Fareez IM, Fong LF, Mandal C, Abu Kasim NH, Kacharaju KR, Soesilawati P. Haque N, et al. World J Stem Cells. 2020 Sep 26;12(9):938-951. doi: 10.4252/wjsc.v12.i9.938. World J Stem Cells. 2020. PMID: 33033556 Free PMC article. Review.
Of these different paracrine factors present within the secretome, researchers have given proper consideration to stromal cell-derived factor-1 (SDF1) that plays a vital role in tissue-specific migration of the cells needed for regeneration. Recently researchers recognized …
Of these different paracrine factors present within the secretome, researchers have given proper consideration to stromal cell-derived facto …
SDF1/CXCR4 axis plays a role in angiogenesis during the degeneration of intervertebral discs.
Zhang H, He B. Zhang H, et al. Mol Med Rep. 2019 Aug;20(2):1203-1211. doi: 10.3892/mmr.2019.10346. Epub 2019 Jun 5. Mol Med Rep. 2019. PMID: 31173219 Free PMC article.
The present study aimed to investigate the influence and relative mechanism of stromal cell derived factor 1 (SDF1) on the angiogenesis of degenerated intervertebral discs. The expression of SDF1 in nucleus pulposus cells (NPCs) was upregulated and downregulated by …
The present study aimed to investigate the influence and relative mechanism of stromal cell derived factor 1 (SDF1) on the angiogenes …
SDF1/CXCR4 axis facilitates the angiogenesis via activating the PI3K/AKT pathway in degenerated discs.
Zhang H, Wang P, Zhang X, Zhao W, Ren H, Hu Z. Zhang H, et al. Mol Med Rep. 2020 Nov;22(5):4163-4172. doi: 10.3892/mmr.2020.11498. Epub 2020 Sep 9. Mol Med Rep. 2020. PMID: 32901877 Free PMC article.
Moreover, SDF1 has been identified to induce neovascularization in rheumatoid arthritis disease. However, the roles of the SDF1/CXCR4 axis in the neovascularization of IDD remain unclear. ...
Moreover, SDF1 has been identified to induce neovascularization in rheumatoid arthritis disease. However, the roles of the SDF1
SDF1/CXCR7 Signaling Axis Participates in Angiogenesis in Degenerated Discs via the PI3K/AKT Pathway.
Zhang H, Wang P, Zhang X, Zhao W, Ren H, Hu Z. Zhang H, et al. DNA Cell Biol. 2019 May;38(5):457-467. doi: 10.1089/dna.2018.4531. Epub 2019 Mar 13. DNA Cell Biol. 2019. PMID: 30864829
In this study, we cocultured human nucleus pulposus cells (NPCs) and vascular endothelial cells (VECs) and regulated the expression of SDF1/CXCR7 to investigate the effect of VEC angiogenesis by NPCs. The results revealed that angiogenesis was enhanced with increased SD
In this study, we cocultured human nucleus pulposus cells (NPCs) and vascular endothelial cells (VECs) and regulated the expression of SD
Prognostic and clinicopathological value of CXCL12/SDF1 expression in breast cancer: A meta-analysis.
Liu H, Li Z, Deng M, Liu Q, Zhang T, Guo W, Li P, Qiao W. Liu H, et al. Clin Chim Acta. 2018 Sep;484:72-80. doi: 10.1016/j.cca.2018.05.041. Epub 2018 May 22. Clin Chim Acta. 2018. PMID: 29800557
Studies investigating the correlation between CXCL12/SDF1 expression and survival in breast carcinoma were included. The pooled hazard ratio (HR) and 95% confidence interval (95% CI) was used to assess the prognostic value of CXCL12/SDF1 in breast cancer. ...CONCLUS …
Studies investigating the correlation between CXCL12/SDF1 expression and survival in breast carcinoma were included. The pooled hazar …
SDF1-3'A polymorphism is associated with increased risk of hematological malignancy: a meta-analysis.
Zhang X, Fan Y, Li Z. Zhang X, et al. Onco Targets Ther. 2017 Mar 14;10:1575-1583. doi: 10.2147/OTT.S130086. eCollection 2017. Onco Targets Ther. 2017. PMID: 28352190 Free PMC article.
CXCL12 (also named SDF1), a member of the chemokine family, has been demonstrated to play an important role in the progression of multiple types of hematological malignancy. ...In addition, SDF1-3'A polymorphism was associated with increased risk of hematological ma …
CXCL12 (also named SDF1), a member of the chemokine family, has been demonstrated to play an important role in the progression of mul …
SDF1-CXCR4 Signaling Maintains Central Post-Stroke Pain through Mediation of Glial-Neuronal Interactions.
Yang F, Luo WJ, Sun W, Wang Y, Wang JL, Yang F, Li CL, Wei N, Wang XL, Guan SM, Chen J. Yang F, et al. Front Mol Neurosci. 2017 Jul 21;10:226. doi: 10.3389/fnmol.2017.00226. eCollection 2017. Front Mol Neurosci. 2017. PMID: 28785202 Free PMC article.
Second, long-term increased-expression of SDF1 and CXCR4 that was accompanied by activations of both microglia and astrocytes following ITC could be blocked by both AMD-3100 and YC-1, a selective inhibitor of HIF-1alpha. ...Taken together, the present study demonstrated th …
Second, long-term increased-expression of SDF1 and CXCR4 that was accompanied by activations of both microglia and astrocytes followi …
Interaction between SDF1 and CXCR4 Promotes Photoreceptor Differentiation via Upregulation of NFkappaB Pathway Signaling Activity in Pax6 Gene-Transfected Photoreceptor Precursors.
Shimizu J, Suzuki T, Hirotsu C, Ueno H, Takada E, Arimitsu N, Ueda Y, Wakisaka S, Suzuki N. Shimizu J, et al. Ophthalmic Res. 2020;63(4):392-403. doi: 10.1159/000503929. Epub 2020 Jan 14. Ophthalmic Res. 2020. PMID: 31935734
SDF1 enhanced human rhodopsin promoter transcription activity, possibly via the NFkappaB pathway. ...Cells in the inner nuclear layer expressed SDF1. CONCLUSIONS: These findings suggest that retinal progenitor cell differentiation was at least partly regulated by
SDF1 enhanced human rhodopsin promoter transcription activity, possibly via the NFkappaB pathway. ...Cells in the inner nuclear layer
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