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An integrated approach to unravel a putative crosstalk network in Alzheimer's disease and Parkinson's disease.
Bisht I, Ambasta RK, Kumar P. Bisht I, et al. Neuropeptides. 2020 Oct;83:102078. doi: 10.1016/j.npep.2020.102078. Epub 2020 Aug 12. Neuropeptides. 2020. PMID: 32807513
We preprocessed and analyzed publicly available microarray datasets and identified 97 DEGs and 21 DEmiRs that may be involved in the overlapped mechanisms between these two disorders. Among the DEGs, we found HSPA9, PGK1, SDHC, FH, DLD, YWHAZ and ACLY as the major protein- …
We preprocessed and analyzed publicly available microarray datasets and identified 97 DEGs and 21 DEmiRs that may be involved in the overlap …
Accelerated aging-related transcriptome alterations in neurovascular unit cells in the brain of Alzheimer's disease.
Zhao Y, Xie YZ, Liu YS. Zhao Y, et al. Front Aging Neurosci. 2022 Aug 18;14:949074. doi: 10.3389/fnagi.2022.949074. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36062157 Free PMC article.
Alzheimer's disease (AD) is the most common cause of dementia with no effective therapies. ...The least absolute shrinkage and selection operator regression method was used to select the crucial AGs most associated with AD: IGF1R, MXI1, RB1, PPARA, NFE2L2, ST …
Alzheimer's disease (AD) is the most common cause of dementia with no effective therapies. ...The least absolute shrink …
The protective effect and bioactive compounds of Astragalus membranaceus against neurodegenerative disorders via alleviating oxidative stress in Drosophila.
Dai Y, Wang Y, Kang Q, Wu Y, Liu Y, Su Y, Wang X, Xiu M, He J. Dai Y, et al. FASEB J. 2024 Jul 15;38(13):e23727. doi: 10.1096/fj.202400390R. FASEB J. 2024. PMID: 38877845
Oxidative stress is proposed as a regulatory element in various neurological disorders, which is involved in the progress of several neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). Antioxidant drugs are widely used to …
Oxidative stress is proposed as a regulatory element in various neurological disorders, which is involved in the progress of several neurode …