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2004 3
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Page 1
SEPT3 as a Potential Molecular Target of Triple-Negative Breast Cancer.
Yang LH, Wang GZ, Gao C. Yang LH, et al. Int J Gen Med. 2024 Apr 25;17:1605-1613. doi: 10.2147/IJGM.S462541. eCollection 2024. Int J Gen Med. 2024. PMID: 38686040 Free PMC article.
Next, the effect of SEPT3 on survival and the association between SEPT3 expression and clinical characteristics were assessed for TNBC patients. ...SEPT3 was observed to be elevated in 112 TNBC significantly. Increased expression of SEPT3 contributed t …
Next, the effect of SEPT3 on survival and the association between SEPT3 expression and clinical characteristics were assessed …
Identification of M5c regulator-medicated methylation modification patterns for prognosis and immune microenvironment in glioma.
Xiao Z, Li J, Liang C, Liu Y, Zhang Y, Zhang Y, Liu Q, Yan X. Xiao Z, et al. Aging (Albany NY). 2023 Nov 6;15(21):12275-12295. doi: 10.18632/aging.205179. Epub 2023 Nov 6. Aging (Albany NY). 2023. PMID: 37934565 Free PMC article.
There were obvious relationships between immune infiltration cells and m5C regulators, especially NSUN7. In the m5C-related module from WGCNA, we found SEPT3, CHI3L1, PLBD1, PHYHIPL, SAMD8, RAP1B, B3GNT5, RER1, PTPN7, SLC39A1, and MXI1 were prognostic factors for glioma, a …
There were obvious relationships between immune infiltration cells and m5C regulators, especially NSUN7. In the m5C-related module from WGCN …
A key piece of the puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and its implications for self-assembly.
Marques da Silva R, Christe Dos Reis Saladino G, Antonio Leonardo D, D'Muniz Pereira H, Andréa Sculaccio S, Paula Ulian Araujo A, Charles Garratt R. Marques da Silva R, et al. J Struct Biol. 2023 Sep;215(3):107983. doi: 10.1016/j.jsb.2023.107983. Epub 2023 Jun 12. J Struct Biol. 2023. PMID: 37315820
The G-interface has properties which place it in between that formed by SEPT2/SEPT6 and SEPT7/SEPT3 in human filaments. Switch I from Cdc10 contributes significantly to the interface, whereas in Cdc3 it is largely disorded. ...
The G-interface has properties which place it in between that formed by SEPT2/SEPT6 and SEPT7/SEPT3 in human filaments. Switch I from …
Analysis of MicroRNA Profile Alterations in Extracellular Vesicles From Mesenchymal Stromal Cells Overexpressing Stem Cell Factor.
Zubkova E, Evtushenko E, Beloglazova I, Osmak G, Koshkin P, Moschenko A, Menshikov M, Parfyonova Y. Zubkova E, et al. Front Cell Dev Biol. 2021 Nov 15;9:754025. doi: 10.3389/fcell.2021.754025. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34869342 Free PMC article.
We assembled the miRNA-based network and found several nodes of target genes among which Vim Sept3 and Vsnl1 are involved in regulation of cellular migration that is consistent with our previous EVs data. ...
We assembled the miRNA-based network and found several nodes of target genes among which Vim Sept3 and Vsnl1 are involved in regulati …
Analyzing mRNAsi-Related Genes Identifies Novel Prognostic Markers and Potential Drug Combination for Patients with Basal Breast Cancer.
Huang K, Wu Y, Xie Y, Huang L, Liu H. Huang K, et al. Dis Markers. 2021 Oct 4;2021:4731349. doi: 10.1155/2021/4731349. eCollection 2021. Dis Markers. 2021. PMID: 34646403 Free PMC article.
This high mRNAsi is also closely related to active cell cycle, DNA replication, and metabolic reprogramming in basal breast cancer. Intriguingly, in the 385 genes, TRIM59, SEPT3, RAD51AP1, and EXO1 can act as independent protective prognostic factors, but CTSF and ABHD4B c …
This high mRNAsi is also closely related to active cell cycle, DNA replication, and metabolic reprogramming in basal breast cancer. Intrigui …
Longitudinal genetic studies of cognitive characteristics.
Mustafin RN, Kazantseva AV, Enikeeva RF, Malykh SB, Khusnutdinova EK. Mustafin RN, et al. Vavilovskii Zhurnal Genet Selektsii. 2020 Feb;24(1):87-95. doi: 10.18699/VJ20.599. Vavilovskii Zhurnal Genet Selektsii. 2020. PMID: 33659785 Free PMC article.
The association between cognitive functioning and genes, which have been previously involved in developing psychiatric disorders (MEF2C, CYP2D6, FAM109B, SEPT3, NAGA, TCF20, NDUFA6 genes), was revealed, thus indicating the role of the similar mechanisms of genetic and neur …
The association between cognitive functioning and genes, which have been previously involved in developing psychiatric disorders (MEF2C, CYP …
Production and analysis of a mammalian septin hetero-octamer complex.
DeRose BT, Kelley RS, Ravi R, Kokona B, Beld J, Spiliotis ET, Padrick SB. DeRose BT, et al. Cytoskeleton (Hoboken). 2020 Nov;77(11):485-499. doi: 10.1002/cm.21643. Epub 2020 Nov 23. Cytoskeleton (Hoboken). 2020. PMID: 33185030 Free PMC article.
In addition, we used this novel tool to resolve recent questions regarding the organization of the soluble septin complex. Biochemical characterization of a SEPT3 truncation that disrupts SEPT3-SEPT3 interactions is consistent with SEPT3 occupying a ce …
In addition, we used this novel tool to resolve recent questions regarding the organization of the soluble septin complex. Biochemical chara …
Molecular Recognition at Septin Interfaces: The Switches Hold the Key.
Rosa HVD, Leonardo DA, Brognara G, Brandão-Neto J, D'Muniz Pereira H, Araújo APU, Garratt RC. Rosa HVD, et al. J Mol Biol. 2020 Oct 2;432(21):5784-5801. doi: 10.1016/j.jmb.2020.09.001. Epub 2020 Sep 7. J Mol Biol. 2020. PMID: 32910969 Free article.
These are formed between SEPT2 and SEPT6 and between SEPT7 and SEPT3, and their description permits an understanding of the structural basis for the selectivity necessary for correct filament assembly. ...
These are formed between SEPT2 and SEPT6 and between SEPT7 and SEPT3, and their description permits an understanding of the structura …
A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface.
Castro DKSDV, da Silva SMO, Pereira HD, Macedo JNA, Leonardo DA, Valadares NF, Kumagai PS, Brandão-Neto J, Araújo APU, Garratt RC. Castro DKSDV, et al. IUCrJ. 2020 Mar 28;7(Pt 3):462-479. doi: 10.1107/S2052252520002973. eCollection 2020 May 1. IUCrJ. 2020. PMID: 32431830 Free PMC article.
Both hexamers and octamers can self-assemble into mixed filaments by end-to-end association, implying that the SEPT3 septins may facilitate polymerization but not necessarily function. ...In the present work, a complete compendium of crystal structures for the GTP-binding …
Both hexamers and octamers can self-assemble into mixed filaments by end-to-end association, implying that the SEPT3 septins may faci …
A blueprint of septin expression in human tissues.
Zuvanov L, Mota DMD, Araujo APU, DeMarco R. Zuvanov L, et al. Funct Integr Genomics. 2019 Sep;19(5):787-797. doi: 10.1007/s10142-019-00690-3. Epub 2019 May 15. Funct Integr Genomics. 2019. PMID: 31089837
Co-expression data between septins suggests two predominant specific complexes in brain tissues and one filament in other tissues. SEPT3 and SEPT5 are two genes highly expressed in the brain and with a strong co-expression in all brain tissues. ...
Co-expression data between septins suggests two predominant specific complexes in brain tissues and one filament in other tissues. SEPT3 …
28 results