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CDC42 Negatively Regulates Testis-Specific SEPT12 Polymerization.
Huang CY, Wang YY, Chen YL, Chen MF, Chiang HS, Kuo PL, Lin YH. Huang CY, et al. Int J Mol Sci. 2018 Sep 5;19(9):2627. doi: 10.3390/ijms19092627. Int J Mol Sci. 2018. PMID: 30189608 Free PMC article.
In mouse models with a defective Septin12 allele, sperm morphology was abnormal, sperm count decreased, and sperms were immotile. ...First, through scanning electron microscopy analysis, we determined that the loss of Septin12 caused defective sperm heads. This indi …
In mouse models with a defective Septin12 allele, sperm morphology was abnormal, sperm count decreased, and sperms were immotile. ... …
Testis-Specific SEPT12 Expression Affects SUN Protein Localization and is Involved in Mammalian Spermiogenesis.
Yeh CH, Wang YY, Wee SK, Chen MF, Chiang HS, Kuo PL, Lin YH. Yeh CH, et al. Int J Mol Sci. 2019 Mar 7;20(5):1163. doi: 10.3390/ijms20051163. Int J Mol Sci. 2019. PMID: 30866452 Free PMC article.
Second, SEPT12 expression altered the nuclear membrane localization of SPAG4, as observed through confocal microscopy, in a human testicular cancer cell line. Third, SEPT12 expression also altered the localizations of nuclear membrane proteins: LAMINA/C in the cells. ...
Second, SEPT12 expression altered the nuclear membrane localization of SPAG4, as observed through confocal microscopy, in a human testicular …