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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
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2011 16
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259 results

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Page 1
SFRP4 Is a Potential Biomarker for the Prognosis and Immunotherapy for Gastric Cancer.
Yu P, He W, Zhang Y, Hu C, Wu Y, Wang Y, Bao Z, Xia Y, Zhang R, Cao M, Yuan L, Cheng X, Xu Z. Yu P, et al. J Oncol. 2022 Jul 5;2022:8829649. doi: 10.1155/2022/8829649. eCollection 2022. J Oncol. 2022. PMID: 35847366 Free PMC article.
Our research aimed to explore the expression of SFRP4 in gastric cancer, its prognostic significance, and its relationship with immune cell infiltration. ...SFRP4 may be important for guiding immunotherapy in gastric cancer patients....
Our research aimed to explore the expression of SFRP4 in gastric cancer, its prognostic significance, and its relationship wit …
An Overview of Ovarian Cancer: The Role of Cancer Stem Cells in Chemoresistance and a Precision Medicine Approach Targeting the Wnt Pathway with the Antagonist sFRP4.
Varier L, Sundaram SM, Gamit N, Warrier S. Varier L, et al. Cancers (Basel). 2023 Feb 17;15(4):1275. doi: 10.3390/cancers15041275. Cancers (Basel). 2023. PMID: 36831617 Free PMC article. Review.
Ovarian cancer is one of the most prevalent gynecological cancers, having a relatively high fatality rate with a low five-year chance of survival when detected in late stages. ...In this review, we first describe types of ovarian cancers, the existing markers …
Ovarian cancer is one of the most prevalent gynecological cancers, having a relatively high fatality rate with a low five-year …
Demethylation of the SFRP4 Promoter Drives Gastric Cancer Progression via the Wnt Pathway.
Li H, Zhao J, Sun J, Tian C, Jiang Q, Ding C, Gan Q, Shu P, Wang X, Qin J, Sun Y. Li H, et al. Mol Cancer Res. 2021 Sep;19(9):1454-1464. doi: 10.1158/1541-7786.MCR-20-0933. Epub 2021 May 20. Mol Cancer Res. 2021. PMID: 34016745
The methylation status of SFRPs was examined in gastric cancer specimens by quantitative methylation analysis. SFRP4 was most upregulated in advanced gastric cancer. ...IMPLICATIONS: In gastric cancer, the expression of SFRP4 was upregulated by …
The methylation status of SFRPs was examined in gastric cancer specimens by quantitative methylation analysis. SFRP4 was most …
SFRP4 drives invasion in gastric cancer and is an early predictor of recurrence.
Busuttil RA, George J, House CM, Lade S, Mitchell C, Di Costanzo NS, Pattison S, Huang YK, Tan P, Cheong JH, Rha SY, Boussioutas A. Busuttil RA, et al. Gastric Cancer. 2021 May;24(3):589-601. doi: 10.1007/s10120-020-01143-8. Epub 2020 Dec 4. Gastric Cancer. 2021. PMID: 33277667 Free PMC article.
OBJECTIVE: Gastric cancer patients generally have a poor outcome, particularly those with advanced-stage disease which is defined by the increased invasion of cancer locally and is associated with higher metastatic potential. ...We evaluated the functional role of a …
OBJECTIVE: Gastric cancer patients generally have a poor outcome, particularly those with advanced-stage disease which is defined by …
SFRP4 gene expression is increased in aggressive prostate cancer.
Sandsmark E, Andersen MK, Bofin AM, Bertilsson H, Drabløs F, Bathen TF, Rye MB, Tessem MB. Sandsmark E, et al. Sci Rep. 2017 Oct 27;7(1):14276. doi: 10.1038/s41598-017-14622-3. Sci Rep. 2017. PMID: 29079735 Free PMC article.
Secreted frizzled-related protein 4 (SFRP4) is a modulator of the cancer-associated Wnt pathway, and previously suggested as a potential marker for prostate cancer aggressiveness. ...Future studies investigating the mechanistic and clinical usefulness of S …
Secreted frizzled-related protein 4 (SFRP4) is a modulator of the cancer-associated Wnt pathway, and previously suggested as a …
Study on the SFRP4 gene polymorphism and expression in prostate cancer.
Natarajan A, Sudha Bandla S, Damodaran M, Sundaram S, Venkatesan V. Natarajan A, et al. J Genet. 2020;99:86. J Genet. 2020. PMID: 33361638 Free article.
Prostate cancer is a heterogeneous disease and considered to be the most commonly diagnosed cancer. ...Fold change was calculated using 2(-deltadeltaCT) method and the results showed that there were a 3.4 and 4.5 fold increase in the sFRP4 expression for GA a …
Prostate cancer is a heterogeneous disease and considered to be the most commonly diagnosed cancer. ...Fold change was calcula …
Sfrp4 is required to maintain Ctsk-lineage periosteal stem cell niche function.
Chen R, Dong H, Raval D, Maridas D, Baroi S, Chen K, Hu D, Berry SR, Baron R, Greenblatt MB, Gori F. Chen R, et al. Proc Natl Acad Sci U S A. 2023 Nov 14;120(46):e2312677120. doi: 10.1073/pnas.2312677120. Epub 2023 Nov 6. Proc Natl Acad Sci U S A. 2023. PMID: 37931101 Free PMC article.
Supporting these findings, Sfrp4 deletion hampers the periosteal response to bone injury and impairs Ctsk-lineage periosteal cell recruitment. Ctsk-lineage PSCs express the PTH receptor and PTH treatment increases the % of PSCs, a response not seen in the absence of Sfr …
Supporting these findings, Sfrp4 deletion hampers the periosteal response to bone injury and impairs Ctsk-lineage periosteal cell rec …
EZH2 regulates sFRP4 expression without affecting the methylation of sFRP4 promoter DNA in colorectal cancer cell lines.
Liu Y, Yu J, Xie Y, Li M, Wang F, Zhang J, Qi J. Liu Y, et al. Exp Ther Med. 2020 Nov;20(5):33. doi: 10.3892/etm.2020.9160. Epub 2020 Sep 1. Exp Ther Med. 2020. PMID: 32952624 Free PMC article.
Abnormal activation of the Wnt signaling pathway is found in 90% of colorectal cancers (CRCs). Secreted frizzled-related protein 4 (sFRP4) serves as an antagonist of the canonical Wnt signaling pathway. ...DNA methylation controls the expression of sFRP4. EZH …
Abnormal activation of the Wnt signaling pathway is found in 90% of colorectal cancers (CRCs). Secreted frizzled-related protein 4 ( …
An Immune-Related Gene Prognostic Index for Head and Neck Squamous Cell Carcinoma.
Chen Y, Li ZY, Zhou GQ, Sun Y. Chen Y, et al. Clin Cancer Res. 2021 Jan 1;27(1):330-341. doi: 10.1158/1078-0432.CCR-20-2166. Epub 2020 Oct 23. Clin Cancer Res. 2021. PMID: 33097495
PURPOSE: To construct an immune-related gene prognostic index (IRGPI) for head and neck squamous cell carcinoma (HNSCC) and clarify the molecular and immune characteristics and the benefit of immune checkpoint inhibitor (ICI) therapy in IRGPI-defined subgroups of HNSCC. EXPERIMEN …
PURPOSE: To construct an immune-related gene prognostic index (IRGPI) for head and neck squamous cell carcinoma (HNSCC) and clarify the mole …
SFRP4 expression correlates with epithelial mesenchymal transition-linked genes and poor overall survival in colon cancer patients.
Nfonsam LE, Jandova J, Jecius HC, Omesiete PN, Nfonsam VN. Nfonsam LE, et al. World J Gastrointest Oncol. 2019 Aug 15;11(8):589-598. doi: 10.4251/wjgo.v11.i8.589. World J Gastrointest Oncol. 2019. PMID: 31435461 Free PMC article.
We previously showed that the WNT "gatekeeper" gene, secreted frizzled-related protein 4 (SFRP4), is over-expressed in early-onset colon cancer. SFRP4 is speculated to play an essential role in cancer by inhibiting the epithelial mesenchymal transition …
We previously showed that the WNT "gatekeeper" gene, secreted frizzled-related protein 4 (SFRP4), is over-expressed in early-onset co …
259 results