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Year Number of Results
1999 2
2000 1
2004 1
2006 1
2007 1
2008 2
2009 1
2010 1
2011 3
2012 1
2013 2
2014 4
2015 4
2017 1
2018 6
2019 6
2020 3
2021 1
2023 3
2024 1

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Page 1
Inflammation-Related Immune-Modulatory SLURP1 Prevents the Proliferation of Human Colon Cancer Cells, and Its Delivery by Salmonella Demonstrates Cross-Species Efficacy against Murine Colon Cancer.
Senevirathne A, Aganja RP, Hewawaduge C, Lee JH. Senevirathne A, et al. Pharmaceutics. 2023 Oct 13;15(10):2462. doi: 10.3390/pharmaceutics15102462. Pharmaceutics. 2023. PMID: 37896222 Free PMC article.
This study investigates the anticancer properties of the alpha7-nAChR antagonist SLURP1 with a specific focus on its effect as an inflammation modulator on human colorectal cancer cell lines Caco2, Colo320DM, and H508 cells. ...However, further investigations are re …
This study investigates the anticancer properties of the alpha7-nAChR antagonist SLURP1 with a specific focus on its effect as an inf …
Unveiling the potential of SLURP1 protein as a biomarker for prostate cancer screening.
Yang T, Liu T, Lei T, Li T, Liu N, Zhang M. Yang T, et al. Front Oncol. 2024 Apr 15;14:1365615. doi: 10.3389/fonc.2024.1365615. eCollection 2024. Front Oncol. 2024. PMID: 38686195 Free PMC article.
Western blot and ELISA further verified the expression changes of SLURP1. The immunohistochemical staining results revealed a substantial increase in positive SLURP1 expression within PCa tumor tissue. Correlation analysis showed a positive correlation between the e …
Western blot and ELISA further verified the expression changes of SLURP1. The immunohistochemical staining results revealed a substan …
Endogenous CHRNA7-ligand SLURP1 as a potential tumor suppressor and anti-nicotinic factor in pancreatic cancer.
Throm VM, Männle D, Giese T, Bauer AS, Gaida MM, Kopitz J, Bruckner T, Plaschke K, Grekova SP, Felix K, Hackert T, Giese NA, Strobel O. Throm VM, et al. Oncotarget. 2018 Jan 24;9(14):11734-11751. doi: 10.18632/oncotarget.24312. eCollection 2018 Feb 20. Oncotarget. 2018. PMID: 29545933 Free PMC article.
Nicotine acts through cholinergic nicotinic receptors, preferentially alpha7 (CHRNA7) that also binds the endogenous ligand SLURP1 (Secreted Ly-6/uPAR-Related Protein 1). The clinical significance of SLURP1 and its interaction with nicotine in PDAC are unclear. ...B …
Nicotine acts through cholinergic nicotinic receptors, preferentially alpha7 (CHRNA7) that also binds the endogenous ligand SLURP1 (S …
IL-22/STAT3-Induced Increases in SLURP1 Expression within Psoriatic Lesions Exerts Antimicrobial Effects against Staphylococcus aureus.
Moriwaki Y, Takada K, Nagasaki T, Kubo N, Ishii T, Kose K, Kageyama T, Tsuji S, Kawashima K, Misawa H. Moriwaki Y, et al. PLoS One. 2015 Oct 16;10(10):e0140750. doi: 10.1371/journal.pone.0140750. eCollection 2015. PLoS One. 2015. PMID: 26474319 Free PMC article.
Moreover, although SLURP1 likely serves as an important proliferation/differentiation factor in keratinocytes, the possible relation between SLURP1 and other skin diseases, such as psoriasis and atopic dermatitis, has not been studied, and the pathophysiological con …
Moreover, although SLURP1 likely serves as an important proliferation/differentiation factor in keratinocytes, the possible relation …
Acetylcholine signaling system in progression of lung cancers.
Friedman JR, Richbart SD, Merritt JC, Brown KC, Nolan NA, Akers AT, Lau JK, Robateau ZR, Miles SL, Dasgupta P. Friedman JR, et al. Pharmacol Ther. 2019 Feb;194:222-254. doi: 10.1016/j.pharmthera.2018.10.002. Epub 2018 Oct 3. Pharmacol Ther. 2019. PMID: 30291908 Free PMC article. Review.
The reason for this trend is due to genome-wide data studies showing that nicotinic receptor subtypes are involved in lung cancer risk, the relationship between cigarette smoke and lung cancer risk as well as the rising popularity of electronic cigarettes considered …
The reason for this trend is due to genome-wide data studies showing that nicotinic receptor subtypes are involved in lung cancer ris …
Emerging Role of Lymphocyte Antigen-6 Family of Genes in Cancer and Immune Cells.
Upadhyay G. Upadhyay G. Front Immunol. 2019 Apr 24;10:819. doi: 10.3389/fimmu.2019.00819. eCollection 2019. Front Immunol. 2019. PMID: 31068932 Free PMC article. Review.
The most interesting of these genes are located on chromosome 8q24.3, a frequently amplified locus in human cancer. Human LY6 genes represent novel biomarkers for poor cancer prognosis and are required for cancer progression in addition to playing an importan …
The most interesting of these genes are located on chromosome 8q24.3, a frequently amplified locus in human cancer. Human LY6 genes r …
In-silico Analyses of Disease Causing Mutations in SLURP1 Gene.
Jafar Hussain HM, Khan R, Li C, Aftab A, Muneer I, Wahab F, Wu L, Jiang X, Xu P. Jafar Hussain HM, et al. Ann Clin Lab Sci. 2019 Nov;49(6):710-721. Ann Clin Lab Sci. 2019. PMID: 31882421
Mutations in the SLURP1 have been reported to cause serious genetic problems of skin, Mal De Meleda, and malignancies. ...Therefore, in present study, we aimed to perform in-silico analyses of the disease causing SLURP1 mutations using online tools. In-total, 21 var …
Mutations in the SLURP1 have been reported to cause serious genetic problems of skin, Mal De Meleda, and malignancies. ...Therefore, …
SLURP1 mutation-impaired T-cell activation in a family with mal de Meleda.
Tjiu JW, Lin PJ, Wu WH, Cheng YP, Chiu HC, Thong HY, Chiang BL, Yang WS, Jee SH. Tjiu JW, et al. Br J Dermatol. 2011 Jan;164(1):47-53. doi: 10.1111/j.1365-2133.2010.10059.x. Epub 2010 Nov 23. Br J Dermatol. 2011. PMID: 20854438
OBJECTIVES: To investigate the association of the SLURP1 gene mutation with T-cell activation in a Taiwanese family with MDM. ...METHODS: Human peripheral blood mononuclear cells (PBMCs) were isolated from a Taiwanese MDM family bearing the G to A substitution in nucleotid …
OBJECTIVES: To investigate the association of the SLURP1 gene mutation with T-cell activation in a Taiwanese family with MDM. ...METH …
Molecular Characterization of Esophageal Squamous Cell Carcinoma Using Quantitative Proteomics.
Mangalaparthi KK, Patel K, Khan AA, Nair B, Kumar RV, Prasad TSK, Sidransky D, Chatterjee A, Pandey A, Gowda H. Mangalaparthi KK, et al. Cancers (Basel). 2023 Jun 23;15(13):3302. doi: 10.3390/cancers15133302. Cancers (Basel). 2023. PMID: 37444412 Free PMC article.
Esophageal squamous cell carcinoma (ESCC) is a heterogeneous cancer associated with a poor prognosis in advanced stages. In India, it is the sixth most common cause of cancer-related mortality. ...In addition, we identified downregulation of esophagus tissue-enriche …
Esophageal squamous cell carcinoma (ESCC) is a heterogeneous cancer associated with a poor prognosis in advanced stages. In India, it …
SLURP-1 is mutated in Mal de Meleda, a potential molecular signature for melanoma and a putative squamous lineage tumor suppressor gene.
Bergqvist C, Kadara H, Hamie L, Nemer G, Safi R, Karouni M, Marrouche N, Abbas O, Hasbani DJ, Kibbi AG, Nassar D, Shimomura Y, Kurban M. Bergqvist C, et al. Int J Dermatol. 2018 Feb;57(2):162-170. doi: 10.1111/ijd.13850. Epub 2017 Dec 12. Int J Dermatol. 2018. PMID: 29231248
Histopathological analysis was performed on biopsies from skin lesions found in the affected individuals. Direct sequencing of SLURP1 was performed in MDM affected members. In silico analysis of publicly available datasets was used to survey SLURP1 mRNA levels in no …
Histopathological analysis was performed on biopsies from skin lesions found in the affected individuals. Direct sequencing of SLURP1 …
40 results