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Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia.
Nat Commun. 2016 Nov 8;7:13331. doi: 10.1038/ncomms13331.
Nat Commun. 2016.
PMID: 27824051
Free PMC article.
Here using RNA sequencing of 560 ALL cases, we identify rearrangements between MEF2D (myocyte enhancer factor 2D) and five genes (BCL9, CSF1R, DAZAP1, HNRNPUL1 and SS18) in 22 B progenitor ALL (B-ALL) cases with a distinct gene expression profile, the most common of …
Here using RNA sequencing of 560 ALL cases, we identify rearrangements between MEF2D (myocyte enhancer factor 2D) and five genes (BCL …
The pathogenic role of MEF2D-SS18 fusion gene in B-cell acute lymphoblastic leukemia.
Zhang M, Mao D, Zhang W.
Zhang M, et al.
Biochem Biophys Res Commun. 2018 Feb 19;496(4):1331-1336. doi: 10.1016/j.bbrc.2018.02.013. Epub 2018 Feb 3.
Biochem Biophys Res Commun. 2018.
PMID: 29408457
In this study, we investigated the pathogenic role of MEF2D-SS18 fusion in B-ALL. The recombinant retrovirus and lentivirus plasmids containing the MEF2D-SS18 transcript were constructed for functional studies. Immuno-fluorescent staining presented the …
In this study, we investigated the pathogenic role of MEF2D-SS18 fusion in B-ALL. The recombinant retrovirus and lentivirus pl …
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