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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
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2005 2
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2007 5
2008 5
2009 5
2010 9
2011 14
2012 13
2013 8
2014 10
2015 13
2016 11
2017 6
2018 10
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2020 12
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2024 5

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156 results

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Page 1
SULF1 Activates the VEGFR2/PI3K/AKT Pathway to Promote the Development of Cervical Cancer.
Li J, Wang X, Li Z, Li M, Zheng X, Zheng D, Wang Y, Xi M. Li J, et al. Curr Cancer Drug Targets. 2023 Aug 4. doi: 10.2174/1568009623666230804161607. Online ahead of print. Curr Cancer Drug Targets. 2023. PMID: 37539927
Our research aimed to investigate the effect of the SULF1-mediated VEGFR2/PI3K/AKT signaling pathway on tumorigenesis and development of cervical cancer (CC). ...In vitro, the upregulation of SULF1 expression in cervical cancer HeLa cells promoted cell …
Our research aimed to investigate the effect of the SULF1-mediated VEGFR2/PI3K/AKT signaling pathway on tumorigenesis and development …
Cancer associated fibroblasts-derived SULF1 promotes gastric cancer metastasis and CDDP resistance through the TGFBR3-mediated TGF-beta signaling pathway.
Fang X, Chen D, Yang X, Cao X, Cheng Q, Liu K, Xu P, Wang Y, Xu J, Zhao S, Yan Z. Fang X, et al. Cell Death Discov. 2024 Mar 4;10(1):111. doi: 10.1038/s41420-024-01882-y. Cell Death Discov. 2024. PMID: 38438372 Free PMC article.
SULF1 has been implicated in a number of malignancies. The function of SULF1 in gastric cancer is disputed. The objective of this study was to examine the role and underlying molecular mechanisms of SULF1 in the context of gastric cancer. We fou …
SULF1 has been implicated in a number of malignancies. The function of SULF1 in gastric cancer is disputed. The objecti …
SULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models.
Brasil da Costa FH, Lewis MS, Truong A, Carson DD, Farach-Carson MC. Brasil da Costa FH, et al. PLoS One. 2020 May 15;15(5):e0230354. doi: 10.1371/journal.pone.0230354. eCollection 2020. PLoS One. 2020. PMID: 32413029 Free PMC article.
Finding that M2-like macrophages increased levels of SULF1 and HSPG2 produced by fibroblasts, we examined SULF1 function in Wnt3A-mediated PCa tumoroid growth in tricultures. Comparing control or SULF1 knockout fibroblastic cells, we showed that SULF1 …
Finding that M2-like macrophages increased levels of SULF1 and HSPG2 produced by fibroblasts, we examined SULF1 function in Wn …
High expression of SULF1 is associated with adverse prognosis in breast cancer brain metastasis.
Li Y, Feng T, Wang Q, Wu Y, Wang J, Zhang W, Kong Q. Li Y, et al. Animal Model Exp Med. 2024 Apr 8. doi: 10.1002/ame2.12406. Online ahead of print. Animal Model Exp Med. 2024. PMID: 38590118 Free article.
In the metastatic breast cancer population, SULF1 ranked top among the 16 DEGs with the highest mutation rate, reaching 11%, primarily due to amplification. ...Currently, docetaxel and vinorelbine can act as treatment options if the expression of SULF1 is hig …
In the metastatic breast cancer population, SULF1 ranked top among the 16 DEGs with the highest mutation rate, reaching 11%, p …
Differential Expression of COL1A1, COL1A2, COL6A3, and SULF1 as Prognostic Biomarkers in Gastric Cancer.
Hu Y, Li J, Luo H, Song W, Yang J. Hu Y, et al. Int J Gen Med. 2021 Sep 17;14:5835-5843. doi: 10.2147/IJGM.S321265. eCollection 2021. Int J Gen Med. 2021. PMID: 34557034 Free PMC article.
BACKGROUND: Gastric cancer (GC) is among the most prevalent cancers globally. As such, there is a need to explore the mechanism underlying its pathogenesis and identify potential biomarkers for its prognosis. ...CONCLUSION: Our findings implicate COL1A1, COL1A2, COL …
BACKGROUND: Gastric cancer (GC) is among the most prevalent cancers globally. As such, there is a need to explore the mechanis …
Genomic landscape of TCRαβ and TCRγδ T-large granular lymphocyte leukemia.
Cheon H, Xing JC, Moosic KB, Ung J, Chan VW, Chung DS, Toro MF, Elghawy O, Wang JS, Hamele CE, Hardison RC, Olson TL, Tan SF, Feith DJ, Ratan A, Loughran TP. Cheon H, et al. Blood. 2022 May 19;139(20):3058-3072. doi: 10.1182/blood.2021013164. Blood. 2022. PMID: 35015834 Free PMC article.
Seventy-six mutations were observed in 3 or more patients in the cohort, and out of those, STAT3, KMT2D, PIK3R1, TTN, EYS, and SULF1 mutations were shared between both subtypes. We identified ARHGAP25, ABCC9, PCDHA11, SULF1, SLC6A15, DDX59, DNMT3A, FAS, KDM6A, KMT2D …
Seventy-six mutations were observed in 3 or more patients in the cohort, and out of those, STAT3, KMT2D, PIK3R1, TTN, EYS, and SULF1 …
Rs3802278 in 3'-UTR of SULF1 associated with platinum resistance and survival in Chinese epithelial ovarian cancer patients.
Zeng F, Liu Y, Ouyang Q, Sun Z, Zhang K, Li X, Liu Y. Zeng F, et al. J Chemother. 2021 Dec;33(8):564-569. doi: 10.1080/1120009X.2021.1913702. Epub 2021 May 24. J Chemother. 2021. PMID: 34029511
Ovarian cancer is the leading cause of death from gynecologic cancers, but platinum resistance remains a major obstacle in the chemotherapy of ovarian cancer. This study aims to examine the role of polymorphisms in sulfatase 1 (SULF1) in platinum resis …
Ovarian cancer is the leading cause of death from gynecologic cancers, but platinum resistance remains a major obstacle in the …
Development of novel monoclonal antibodies and immunoassays for sensitive and specific detection of SULF1 endosulfatase.
Yang YW, Phillips JJ, Jablons DM, Lemjabbar-Alaoui H. Yang YW, et al. Biochim Biophys Acta Gen Subj. 2021 Feb;1865(2):129802. doi: 10.1016/j.bbagen.2020.129802. Epub 2020 Dec 1. Biochim Biophys Acta Gen Subj. 2021. PMID: 33276062 Free PMC article.
The expression of Sulf1 is altered in many cancers. Further studies are needed to clarify Sulf1 role in tumorigenesis, and new tools that can expand our knowledge in this field are required. ...RESULTS: This study reports novel mAbs and immunoassays developed …
The expression of Sulf1 is altered in many cancers. Further studies are needed to clarify Sulf1 role in tumorigenesis, …
Incorporating SULF1 polymorphisms in a pretreatment CT-based radiomic model for predicting platinum resistance in ovarian cancer treatment.
Yi X, Liu Y, Zhou B, Xiang W, Deng A, Fu Y, Zhao Y, Ouyang Q, Liu Y, Sun Z, Zhang K, Li X, Zeng F, Zhou H, Chen BT. Yi X, et al. Biomed Pharmacother. 2021 Jan;133:111013. doi: 10.1016/j.biopha.2020.111013. Epub 2020 Nov 20. Biomed Pharmacother. 2021. PMID: 33227705 Free article.
OBJECTIVE: Early detection of platinum resistance for ovarian cancer treatment remains challenging. This study aims to develop a machine learning model incorporating genomic data such as Single-Nucleotide Polymorphisms (SNPs) of Human Sulfatase 1 (SULF1) with a CT r …
OBJECTIVE: Early detection of platinum resistance for ovarian cancer treatment remains challenging. This study aims to develop a mach …
The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.
Lai JP, Sandhu DS, Shire AM, Roberts LR. Lai JP, et al. J Gastrointest Cancer. 2008;39(1-4):149-58. doi: 10.1007/s12029-009-9058-y. Epub 2009 Apr 17. J Gastrointest Cancer. 2008. PMID: 19373441 Free PMC article. Review.
SULF1 is downregulated in the majority of cancer cell lines examined, and forced expression of SULF1 decreases cell proliferation, migration, and invasion. ...CONCLUSION: Strategies targeting SULF1 or the interaction between SULF1 and the relate …
SULF1 is downregulated in the majority of cancer cell lines examined, and forced expression of SULF1 decreases cell pro …
156 results