Saavedra HI - Search Results

1

The G1 phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification.

Harrison MK, Adon AM, Saavedra HI. Harrison MK, et al. Among authors: saavedra hi. Cell Div. 2011 Jan 27;6:2. doi: 10.1186/1747-1028-6-2. Cell Div. 2011. PMID: 21272329 Free PMC article.

2

Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.

Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI. Adon AM, et al. Among authors: saavedra hi. Mol Cell Biol. 2010 Feb;30(3):694-710. doi: 10.1128/MCB.00253-09. Epub 2009 Nov 23. Mol Cell Biol. 2010. PMID: 19933848 Free PMC article.

3

The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2.

Zeng X, Shaikh FY, Harrison MK, Adon AM, Trimboli AJ, Carroll KA, Sharma N, Timmers C, Chodosh LA, Leone G, Saavedra HI. Zeng X, et al. Among authors: saavedra hi. Oncogene. 2010 Sep 9;29(36):5103-12. doi: 10.1038/onc.2010.253. Epub 2010 Jun 28. Oncogene. 2010. PMID: 20581865 Free PMC article.

4

Correction for Adon et al., "Cdk2 and Cdk4 Regulate the Centrosome Cycle and Are Critical Mediators of Centrosome Amplification in p53-Null Cells".

Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI. Adon AM, et al. Among authors: saavedra hi. Mol Cell Biol. 2020 Nov 6;40(23):e00488-20. doi: 10.1128/MCB.00488-20. Print 2020 Nov 6. Mol Cell Biol. 2020. PMID: 33159003 Free PMC article. No abstract available.

5

Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway.

Ramachandiran S, Adon A, Guo X, Wang Y, Wang H, Chen Z, Kowalski J, Sunay UR, Young AN, Brown T, Mar JC, Du Y, Fu H, Mann KP, Natkunam Y, Boise LH, Saavedra HI, Lossos IS, Bernal-Mizrachi L. Ramachandiran S, et al. Among authors: saavedra hi. Int J Cancer. 2015 May 15;136(10):2341-51. doi: 10.1002/ijc.29301. Epub 2014 Nov 11. Int J Cancer. 2015. PMID: 25359525 Free PMC article.

6

Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells.

Lee MY, Marina M, King JL, Saavedra HI. Lee MY, et al. Among authors: saavedra hi. Cell Div. 2014 Sep 25;9:3. doi: 10.1186/1747-1028-9-3. eCollection 2014. Cell Div. 2014. PMID: 25278993 Free PMC article.

7

Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis.

Hagen KR, Zeng X, Lee MY, Tucker Kahn S, Harrison Pitner MK, Zaky SS, Liu Y, O'Regan RM, Deng X, Saavedra HI. Hagen KR, et al. Among authors: saavedra hi. Cell Div. 2013 Jul 25;8(1):10. doi: 10.1186/1747-1028-8-10. Cell Div. 2013. PMID: 23886499 Free PMC article.

8

Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model.

Harrison Pitner MK, Saavedra HI. Harrison Pitner MK, et al. Among authors: saavedra hi. PLoS One. 2013 Jun 11;8(6):e65971. doi: 10.1371/journal.pone.0065971. Print 2013. PLoS One. 2013. PMID: 23776583 Free PMC article.

9

Nek2 and Plk4: prognostic markers, drivers of breast tumorigenesis and drug resistance.

Marina M, Saavedra HI. Marina M, et al. Among authors: saavedra hi. Front Biosci (Landmark Ed). 2014 Jan 1;19(2):352-65. doi: 10.2741/4212. Front Biosci (Landmark Ed). 2014. PMID: 24389189 Free PMC article. Review.

10

Inactivation of E2F3 results in centrosome amplification.

Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G. Saavedra HI, et al. Cancer Cell. 2003 Apr;3(4):333-46. doi: 10.1016/s1535-6108(03)00083-7. Cancer Cell. 2003. PMID: 12726860 Free PMC article.

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