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An analysis of protocols and publications suggested that most discontinuations of clinical trials were not based on preplanned interim analyses or stopping rules.
Stegert M, Kasenda B, von Elm E, You JJ, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Briel M; DISCO study group. Stegert M, et al. Among authors: saccilotto r. J Clin Epidemiol. 2016 Jan;69:152-60. doi: 10.1016/j.jclinepi.2015.05.023. Epub 2015 Jun 4. J Clin Epidemiol. 2016. PMID: 26361993 Review.
Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study).
Kasenda B, von Elm EB, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl J, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla S, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Rosenthal R, Schandelmaier S, Sun X, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Bucher HC, Guyatt GH, Briel M. Kasenda B, et al. Among authors: saccilotto r. BMC Med Res Methodol. 2012 Aug 28;12:131. doi: 10.1186/1471-2288-12-131. BMC Med Res Methodol. 2012. PMID: 22928744 Free PMC article.
Prevalence, characteristics, and publication of discontinued randomized trials.
Kasenda B, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Schandelmaier S, Xin S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M. Kasenda B, et al. Among authors: saccilotto r. JAMA. 2014 Mar 12;311(10):1045-51. doi: 10.1001/jama.2014.1361. JAMA. 2014. PMID: 24618966 Free article.
Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study.
Rosenthal R, Kasenda B, Dell-Kuster S, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla S, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Olu KK, Raatz H, Moja L, Ebrahim S, Schandelmaier S, Sun X, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M. Rosenthal R, et al. Among authors: saccilotto r. Ann Surg. 2015 Jul;262(1):68-73. doi: 10.1097/SLA.0000000000000810. Ann Surg. 2015. PMID: 24979608 Free article.
Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications.
Kasenda B, Schandelmaier S, Sun X, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M; DISCO Study Group. Kasenda B, et al. Among authors: saccilotto r. BMJ. 2014 Jul 16;349:g4539. doi: 10.1136/bmj.g4539. BMJ. 2014. PMID: 25030633 Free PMC article.
Fibrates for primary prevention of cardiovascular disease events.
Nordmann AJ, Ferreira-González I, Kasenda B, Saccilotto R, Bassler D, Bhatnagar N, Briel M. Nordmann AJ, et al. Among authors: saccilotto r. Cochrane Database Syst Rev. 2012;(3):CD009753. doi: 10.1002/14651858.CD009753. Cochrane Database Syst Rev. 2012. PMID: 25267898 Free PMC article. Updated.
Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study.
Schandelmaier S, von Elm E, You JJ, Blümle A, Tomonaga Y, Lamontagne F, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Sun X, Bassler D, Busse JW, Ferreira-González I, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Cook DJ, Meade MO, Bucher HC, Kasenda B, Briel M. Schandelmaier S, et al. Among authors: saccilotto r. Crit Care Med. 2016 Jan;44(1):130-7. doi: 10.1097/CCM.0000000000001369. Crit Care Med. 2016. PMID: 26468895 Free article.
Planning and reporting of quality-of-life outcomes in cancer trials.
Schandelmaier S, Conen K, von Elm E, You JJ, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Sun X, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M, Kasenda B; DISCO study group. Schandelmaier S, et al. Among authors: saccilotto r. Ann Oncol. 2016 Jan;27(1):209. doi: 10.1093/annonc/mdv559. Epub 2015 Nov 25. Ann Oncol. 2016. PMID: 26612098 Free PMC article. No abstract available.
Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.
Kasenda B, von Elm E, You JJ, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Ebrahim S, Schandelmaier S, Sun X, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M. Kasenda B, et al. Among authors: saccilotto r. PLoS Med. 2016 Jun 28;13(6):e1002046. doi: 10.1371/journal.pmed.1002046. eCollection 2016 Jun. PLoS Med. 2016. PMID: 27352244 Free PMC article.
Premature Discontinuation of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study.
Schandelmaier S, Tomonaga Y, Bassler D, Meerpohl JJ, von Elm E, You JJ, Bluemle A, Lamontagne F, Saccilotto R, Amstutz A, Bengough T, Stegert M, Olu KK, Tikkinen KAO, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Sun X, Busse JW, Ferreira-González I, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Guyatt G, Bucher HC, Kasenda B, Briel M. Schandelmaier S, et al. Among authors: saccilotto r. J Pediatr. 2017 May;184:209-214.e1. doi: 10.1016/j.jpeds.2017.01.071. Epub 2017 Mar 3. J Pediatr. 2017. PMID: 28410086
44 results