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Nascent polypeptide sequences that influence ribosome function.
Cruz-Vera LR, Sachs MS, Squires CL, Yanofsky C. Cruz-Vera LR, et al. Among authors: sachs ms. Curr Opin Microbiol. 2011 Apr;14(2):160-6. doi: 10.1016/j.mib.2011.01.011. Epub 2011 Feb 20. Curr Opin Microbiol. 2011. PMID: 21342782 Review.
Site-specific release of nascent chains from ribosomes at a sense codon.
Doronina VA, Wu C, de Felipe P, Sachs MS, Ryan MD, Brown JD. Doronina VA, et al. Among authors: sachs ms. Mol Cell Biol. 2008 Jul;28(13):4227-39. doi: 10.1128/MCB.00421-08. Epub 2008 May 5. Mol Cell Biol. 2008. PMID: 18458056 Free PMC article.
Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan.
Martínez AK, Gordon E, Sengupta A, Shirole N, Klepacki D, Martinez-Garriga B, Brown LM, Benedik MJ, Yanofsky C, Mankin AS, Vazquez-Laslop N, Sachs MS, Cruz-Vera LR. Martínez AK, et al. Among authors: sachs ms. Nucleic Acids Res. 2014 Jan;42(2):1245-56. doi: 10.1093/nar/gkt923. Epub 2013 Oct 16. Nucleic Acids Res. 2014. PMID: 24137004 Free PMC article.
Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function.
Martínez AK, Shirole NH, Murakami S, Benedik MJ, Sachs MS, Cruz-Vera LR. Martínez AK, et al. Among authors: sachs ms. Nucleic Acids Res. 2012 Mar;40(5):2247-57. doi: 10.1093/nar/gkr1052. Epub 2011 Nov 21. Nucleic Acids Res. 2012. PMID: 22110039 Free PMC article.
Dissection of a co-translational nascent chain separation event.
Doronina VA, de Felipe P, Wu C, Sharma P, Sachs MS, Ryan MD, Brown JD. Doronina VA, et al. Among authors: sachs ms. Biochem Soc Trans. 2008 Aug;36(Pt 4):712-6. doi: 10.1042/BST0360712. Biochem Soc Trans. 2008. PMID: 18631146
Sequence requirements for ribosome stalling by the arginine attenuator peptide.
Spevak CC, Ivanov IP, Sachs MS. Spevak CC, et al. Among authors: sachs ms. J Biol Chem. 2010 Dec 24;285(52):40933-42. doi: 10.1074/jbc.M110.164152. Epub 2010 Sep 30. J Biol Chem. 2010. PMID: 20884617 Free PMC article.
Evolutionary roles of upstream open reading frames in mediating gene regulation in fungi.
Hood HM, Neafsey DE, Galagan J, Sachs MS. Hood HM, et al. Among authors: sachs ms. Annu Rev Microbiol. 2009;63:385-409. doi: 10.1146/annurev.micro.62.081307.162835. Annu Rev Microbiol. 2009. PMID: 19514854 Review.
Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay.
Gaba A, Jacobson A, Sachs MS. Gaba A, et al. Among authors: sachs ms. Mol Cell. 2005 Nov 11;20(3):449-60. doi: 10.1016/j.molcel.2005.09.019. Mol Cell. 2005. PMID: 16285926
A nascent polypeptide domain that can regulate translation elongation.
Fang P, Spevak CC, Wu C, Sachs MS. Fang P, et al. Among authors: sachs ms. Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4059-64. doi: 10.1073/pnas.0400554101. Epub 2004 Mar 12. Proc Natl Acad Sci U S A. 2004. PMID: 15020769 Free PMC article.
The Neurospora crassa arg-2 locus. Structure and expression of the gene encoding the small subunit of arginine-specific carbamoyl phosphate synthetase.
Orbach MJ, Sachs MS, Yanofsky C. Orbach MJ, et al. Among authors: sachs ms. J Biol Chem. 1990 Jul 5;265(19):10981-7. J Biol Chem. 1990. PMID: 2141606
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