Saecker RM - Search Results

1

Enthalpy and heat capacity changes for formation of an oligomeric DNA duplex: interpretation in terms of coupled processes of formation and association of single-stranded helices.

Holbrook JA, Capp MW, Saecker RM, Record MT Jr. Holbrook JA, et al. Among authors: saecker rm. Biochemistry. 1999 Jun 29;38(26):8409-22. doi: 10.1021/bi990043w. Biochemistry. 1999. PMID: 10387087

2

Preferential interactions of glycine betaine and of urea with DNA: implications for DNA hydration and for effects of these solutes on DNA stability.

Hong J, Capp MW, Anderson CF, Saecker RM, Felitsky DJ, Anderson MW, Record MT Jr. Hong J, et al. Among authors: saecker rm. Biochemistry. 2004 Nov 23;43(46):14744-58. doi: 10.1021/bi049096q. Biochemistry. 2004. PMID: 15544345

3

Use of urea and glycine betaine to quantify coupled folding and probe the burial of DNA phosphates in lac repressor-lac operator binding.

Hong J, Capp MW, Saecker RM, Record MT Jr. Hong J, et al. Among authors: saecker rm. Biochemistry. 2005 Dec 27;44(51):16896-911. doi: 10.1021/bi0515218. Biochemistry. 2005. PMID: 16363803 Free PMC article.

4

Solute probes of conformational changes in open complex (RPo) formation by Escherichia coli RNA polymerase at the lambdaPR promoter: evidence for unmasking of the active site in the isomerization step and for large-scale coupled folding in the subsequent conversion to RPo.

Kontur WS, Saecker RM, Davis CA, Capp MW, Record MT Jr. Kontur WS, et al. Among authors: saecker rm. Biochemistry. 2006 Feb 21;45(7):2161-77. doi: 10.1021/bi051835v. Biochemistry. 2006. PMID: 16475805 Free PMC article.

5

Interactions of the osmolyte glycine betaine with molecular surfaces in water: thermodynamics, structural interpretation, and prediction of m-values.

Capp MW, Pegram LM, Saecker RM, Kratz M, Riccardi D, Wendorff T, Cannon JG, Record MT Jr. Capp MW, et al. Among authors: saecker rm. Biochemistry. 2009 Nov 3;48(43):10372-9. doi: 10.1021/bi901273r. Biochemistry. 2009. PMID: 19757837 Free PMC article.

6

Probing DNA binding, DNA opening, and assembly of a downstream clamp/jaw in Escherichia coli RNA polymerase-lambdaP(R) promoter complexes using salt and the physiological anion glutamate.

Kontur WS, Capp MW, Gries TJ, Saecker RM, Record MT Jr. Kontur WS, et al. Among authors: saecker rm. Biochemistry. 2010 May 25;49(20):4361-73. doi: 10.1021/bi100092a. Biochemistry. 2010. PMID: 20201585 Free PMC article.

7

Thermodynamic analysis of interactions between denaturants and protein surface exposed on unfolding: interpretation of urea and guanidinium chloride m-values and their correlation with changes in accessible surface area (ASA) using preferential interaction coefficients and the local-bulk domain model.

Courtenay ES, Capp MW, Saecker RM, Record MT Jr. Courtenay ES, et al. Among authors: saecker rm. Proteins. 2000;Suppl 4:72-85. doi: 10.1002/1097-0134(2000)41:4+<72::aid-prot70>3.0.co;2-7. Proteins. 2000. PMID: 11013402

8

Specific and non-specific interactions of integration host factor with DNA: thermodynamic evidence for disruption of multiple IHF surface salt-bridges coupled to DNA binding.

Holbrook JA, Tsodikov OV, Saecker RM, Record MT Jr. Holbrook JA, et al. Among authors: saecker rm. J Mol Biol. 2001 Jul 6;310(2):379-401. doi: 10.1006/jmbi.2001.4768. J Mol Biol. 2001. PMID: 11428896

9

Fluorescence Resonance Energy Transfer Characterization of DNA Wrapping in Closed and Open Escherichia coli RNA Polymerase-λP(R) Promoter Complexes.

Sreenivasan R, Heitkamp S, Chhabra M, Saecker R, Lingeman E, Poulos M, McCaslin D, Capp MW, Artsimovitch I, Record MT Jr. Sreenivasan R, et al. Biochemistry. 2016 Apr 12;55(14):2174-86. doi: 10.1021/acs.biochem.6b00125. Epub 2016 Mar 31. Biochemistry. 2016. PMID: 26998673 Free PMC article.

10

Kinetic studies and structural models of the association of E. coli sigma(70) RNA polymerase with the lambdaP(R) promoter: large scale conformational changes in forming the kinetically significant intermediates.

Saecker RM, Tsodikov OV, McQuade KL, Schlax PE Jr, Capp MW, Record MT Jr. Saecker RM, et al. J Mol Biol. 2002 Jun 7;319(3):649-71. doi: 10.1016/S0022-2836(02)00293-0. J Mol Biol. 2002. PMID: 12054861

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