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Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response.
Zhang P, Kitchen-Smith I, Xiong L, Stracquadanio G, Brown K, Richter PH, Wallace MD, Bond E, Sahgal N, Moore S, Nornes S, De Val S, Surakhy M, Sims D, Wang X, Bell DA, Zeron-Medina J, Jiang Y, Ryan AJ, Selfe JL, Shipley J, Kar S, Pharoah PD, Loveday C, Jansen R, Grochola LF, Palles C, Protheroe A, Millar V, Ebner DV, Pagadala M, Blagden SP, Maughan TS, Domingo E, Tomlinson I, Turnbull C, Carter H, Bond GL. Zhang P, et al. Among authors: sahgal n. Cancer Res. 2021 Apr 1;81(7):1667-1680. doi: 10.1158/0008-5472.CAN-20-0177. Epub 2021 Feb 8. Cancer Res. 2021. PMID: 33558336 Free PMC article.
Tocilizumab as a Therapeutic Agent for Critically Ill Patients Infected with SARS-CoV-2.
Petrak RM, Skorodin NC, Van Hise NW, Fliegelman RM, Pinsky J, Didwania V, Anderson M, Diaz M, Shah K, Chundi VV, Hines DW, Harting BP, Sidwha K, Yu B, Brune P, Owaisi A, Beezhold D, Kent J, Vais D, Han A, Gowda N, Sahgal N, Silverman J, Stake J, Nepomuceno J, Heddurshetti R. Petrak RM, et al. Among authors: sahgal n. Clin Transl Sci. 2021 Nov;14(6):2146-2151. doi: 10.1111/cts.12894. Epub 2021 Oct 27. Clin Transl Sci. 2021. PMID: 32918792 Free PMC article.
Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits.
Di Giovannantonio M, Harris BH, Zhang P, Kitchen-Smith I, Xiong L, Sahgal N, Stracquadanio G, Wallace M, Blagden S, Lord S, Harris D, Harris AHL, Buffa FM, Bond GL. Di Giovannantonio M, et al. Among authors: sahgal n. J Med Genet. 2021 Jun;58(6):392-399. doi: 10.1136/jmedgenet-2019-106799. Epub 2020 Jun 26. J Med Genet. 2021. PMID: 32591342 Free PMC article.
Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma.
MacGregor TP, Carter R, Gillies RS, Findlay JM, Kartsonaki C, Castro-Giner F, Sahgal N, Wang LM, Chetty R, Maynard ND, Cazier JB, Buffa F, McHugh PJ, Tomlinson I, Middleton MR, Sharma RA. MacGregor TP, et al. Among authors: sahgal n. Sci Rep. 2018 May 8;8(1):7265. doi: 10.1038/s41598-018-24232-2. Sci Rep. 2018. PMID: 29739952 Free PMC article. Clinical Trial.
50 results