Sakaki T - Search Results

1

Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.

Kato Y, Ikushiro S, Emi Y, Tamaki S, Suzuki H, Sakaki T, Yamada S, Degawa M. Kato Y, et al. Among authors: sakaki t. Drug Metab Dispos. 2008 Jan;36(1):51-5. doi: 10.1124/dmd.107.018184. Epub 2007 Oct 1. Drug Metab Dispos. 2008. PMID: 17908920

2

Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24.

Sakaki T, Sawada N, Komai K, Shiozawa S, Yamada S, Yamamoto K, Ohyama Y, Inouye K. Sakaki T, et al. Eur J Biochem. 2000 Oct;267(20):6158-65. doi: 10.1046/j.1432-1327.2000.01680.x. Eur J Biochem. 2000. PMID: 11012668 Free article.

Human CYP24 demonstrated a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways towards both 25(OH)D3 and 1alpha,25(OH)2D3, whereas rat CYP24 showed almost no C-23 hydroxylation pathway [Sakaki, T. Sawada, N. Nonaka, Y. Ohyama, Y. & Inou …

Human CYP24 demonstrated a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways towards both 25(OH)D3 and 1alpha,25 …

3

Sequential metabolism of 2,3,7-trichlorodibenzo-p-dioxin (2,3,7-triCDD) by cytochrome P450 and UDP-glucuronosyltransferase in human liver microsomes.

Kasai N, Sakaki T, Shinkyo R, Ikushiro S, Iyanagi T, Kamao M, Okano T, Ohta M, Inouye K. Kasai N, et al. Among authors: sakaki t. Drug Metab Dispos. 2004 Aug;32(8):870-5. doi: 10.1124/dmd.32.8.870. Drug Metab Dispos. 2004. PMID: 15258113

4

Metabolism of 26,26,26,27,27,27-F6-1 alpha,23S,25-trihydroxyvitamin D3 by human UDP-glucuronosyltransferase 1A3.

Kasai N, Sakaki T, Shinkyo R, Ikushiro S, Iyanagi T, Ohta M, Inouye K. Kasai N, et al. Among authors: sakaki t. Drug Metab Dispos. 2005 Jan;33(1):102-7. doi: 10.1124/dmd.104.002303. Epub 2004 Oct 26. Drug Metab Dispos. 2005. PMID: 15507540

5

Biodegradation of dioxins by recombinant Escherichia coli expressing rat CYP1A1 or its mutant.

Shinkyo R, Kamakura M, Ikushiro S, Inouye K, Sakaki T. Shinkyo R, et al. Among authors: sakaki t. Appl Microbiol Biotechnol. 2006 Sep;72(3):584-90. doi: 10.1007/s00253-005-0286-1. Epub 2006 Feb 18. Appl Microbiol Biotechnol. 2006. PMID: 16489453

6

Monospecific antipeptide antibodies against human hepatic UDP-glucuronosyltransferase 1A subfamily (UGT1A) isoforms.

Ikushiro S, Emi Y, Kato Y, Yamada S, Sakaki T. Ikushiro S, et al. Among authors: sakaki t. Drug Metab Pharmacokinet. 2006 Feb;21(1):70-4. doi: 10.2133/dmpk.21.70. Drug Metab Pharmacokinet. 2006. PMID: 16547396 Free article.

7

Interaction between mitochondrial CYP27B1 and adrenodoxin: role of arginine 458 of mouse CYP27B1.

Urushino N, Yamamoto K, Kagawa N, Ikushiro S, Kamakura M, Yamada S, Kato S, Inouye K, Sakaki T. Urushino N, et al. Among authors: sakaki t. Biochemistry. 2006 Apr 11;45(14):4405-12. doi: 10.1021/bi060072o. Biochemistry. 2006. PMID: 16584176

8

Enzymatic properties of human CYP2W1 expressed in Escherichia coli.

Yoshioka H, Kasai N, Ikushiro S, Shinkyo R, Kamakura M, Ohta M, Inouye K, Sakaki T. Yoshioka H, et al. Among authors: sakaki t. Biochem Biophys Res Commun. 2006 Jun 23;345(1):169-74. doi: 10.1016/j.bbrc.2006.04.080. Epub 2006 Apr 27. Biochem Biophys Res Commun. 2006. PMID: 16677611

9

Role of Gln 85 of human CYP27A1 in 25-hydroxyvitamin D(3)-binding and protein folding.

Sawada N, Yamamoto K, Yamada S, Ikushiro S, Kamakura M, Ohta M, Inouye K, Sakaki T. Sawada N, et al. Among authors: sakaki t. Biochem Biophys Res Commun. 2007 Mar 30;355(1):211-6. doi: 10.1016/j.bbrc.2007.01.158. Epub 2007 Feb 6. Biochem Biophys Res Commun. 2007. PMID: 17292862

10

Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms.

Fujiwara R, Nakajima M, Yamanaka H, Nakamura A, Katoh M, Ikushiro S, Sakaki T, Yokoi T. Fujiwara R, et al. Among authors: sakaki t. Drug Metab Dispos. 2007 May;35(5):747-57. doi: 10.1124/dmd.106.014191. Epub 2007 Feb 9. Drug Metab Dispos. 2007. PMID: 17293379

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