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Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance.
Hahm S, Mizuno TM, Wu TJ, Wisor JP, Priest CA, Kozak CA, Boozer CN, Peng B, McEvoy RC, Good P, Kelley KA, Takahashi JS, Pintar JE, Roberts JL, Mobbs CV, Salton SR. Hahm S, et al. Among authors: salton sr. Neuron. 1999 Jul;23(3):537-48. doi: 10.1016/s0896-6273(00)80806-5. Neuron. 1999. PMID: 10433265 Free article.
Germline ablation of VGF increases lipolysis in white adipose tissue.
Fargali S, Scherer T, Shin AC, Sadahiro M, Buettner C, Salton SR. Fargali S, et al. Among authors: salton sr. J Endocrinol. 2012 Nov;215(2):313-22. doi: 10.1530/JOE-12-0172. Epub 2012 Aug 31. J Endocrinol. 2012. PMID: 22942234 Free PMC article.
VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting.
Hahm S, Fekete C, Mizuno TM, Windsor J, Yan H, Boozer CN, Lee C, Elmquist JK, Lechan RM, Mobbs CV, Salton SR. Hahm S, et al. Among authors: salton sr. J Neurosci. 2002 Aug 15;22(16):6929-38. doi: 10.1523/JNEUROSCI.22-16-06929.2002. J Neurosci. 2002. PMID: 12177191 Free PMC article.
90 results