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Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.
Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, Pinsky L, Kakizuka A, Ross CA, Nicholson DW, Bredesen DE, Hayden MR. Wellington CL, et al. Among authors: salvesen gs. J Biol Chem. 1998 Apr 10;273(15):9158-67. doi: 10.1074/jbc.273.15.9158. J Biol Chem. 1998. PMID: 9535906 Free article.
Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity.
Ellerby LM, Andrusiak RL, Wellington CL, Hackam AS, Propp SS, Wood JD, Sharp AH, Margolis RL, Ross CA, Salvesen GS, Hayden MR, Bredesen DE. Ellerby LM, et al. Among authors: salvesen gs. J Biol Chem. 1999 Mar 26;274(13):8730-6. doi: 10.1074/jbc.274.13.8730. J Biol Chem. 1999. PMID: 10085113 Free article.
Pro-caspase-3 is a major physiologic target of caspase-8.
Stennicke HR, Jürgensmeier JM, Shin H, Deveraux Q, Wolf BB, Yang X, Zhou Q, Ellerby HM, Ellerby LM, Bredesen D, Green DR, Reed JC, Froelich CJ, Salvesen GS. Stennicke HR, et al. Among authors: salvesen gs. J Biol Chem. 1998 Oct 16;273(42):27084-90. doi: 10.1074/jbc.273.42.27084. J Biol Chem. 1998. PMID: 9765224 Free article.
Human ICE/CED-3 protease nomenclature.
Alnemri ES, Livingston DJ, Nicholson DW, Salvesen G, Thornberry NA, Wong WW, Yuan J. Alnemri ES, et al. Cell. 1996 Oct 18;87(2):171. doi: 10.1016/s0092-8674(00)81334-3. Cell. 1996. PMID: 8861900 Free article. No abstract available.
321 results