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Shiga toxin-producing Escherichia coli infection: temporal and quantitative relationships among colonization, toxin production, and systemic disease.
Cornick NA, Matise I, Samuel JE, Bosworth BT, Moon HW. Cornick NA, et al. Among authors: samuel je. J Infect Dis. 2000 Jan;181(1):242-51. doi: 10.1086/315172. J Infect Dis. 2000. PMID: 10608773
Edema disease, a naturally occurring disease of swine caused by Shiga toxin-producing Escherichia coli (STEC), was used as a model for the sequence of events that occur in the pathogenesis of STEC infection. The mean time from production of levels of Shiga …
Edema disease, a naturally occurring disease of swine caused by Shiga toxin-producing Escherichia coli (STEC), was used as a m …
Identification of three amino acid residues in the B subunit of Shiga toxin and Shiga-like toxin type II that are essential for holotoxin activity.
Perera LP, Samuel JE, Holmes RK, O'Brien AD. Perera LP, et al. Among authors: samuel je. J Bacteriol. 1991 Feb;173(3):1151-60. doi: 10.1128/jb.173.3.1151-1160.1991. J Bacteriol. 1991. PMID: 1991714 Free PMC article.
Shiga toxin of Shigella dysenteriae type I and Shiga-like toxins I and II (SLT-I and SLT-II, respectively) of enterohemorrhagic Escherichia coli are functionally similar protein cytotoxins. ...The analogous arginine, alanine, and glycine residues were conserv …
Shiga toxin of Shigella dysenteriae type I and Shiga-like toxins I and II (SLT-I and SLT-II, respectively) of enterohem …
Vaccination with genetically modified Shiga-like toxin IIe prevents edema disease in swine.
Bosworth BT, Samuel JE, Moon HW, O'Brien AD, Gordon VM, Whipp SC. Bosworth BT, et al. Among authors: samuel je. Infect Immun. 1996 Jan;64(1):55-60. doi: 10.1128/iai.64.1.55-60.1996. Infect Immun. 1996. PMID: 8557374 Free PMC article. Clinical Trial.
Escherichia coli strains producing Shiga-like toxin II variant (SLT-IIe, formerly called SLT-IIv) cause edema disease in weaned pigs. Vaccination of pigs with a genetically modified form of Shiga-like toxin IIe, SLT-IIe(E167Q), has been previously show …
Escherichia coli strains producing Shiga-like toxin II variant (SLT-IIe, formerly called SLT-IIv) cause edema disease in weane …
Cloning and sequencing of a Shiga-like toxin type II variant from Escherichia coli strain responsible for edema disease of swine.
Weinstein DL, Jackson MP, Samuel JE, Holmes RK, O'Brien AD. Weinstein DL, et al. Among authors: samuel je. J Bacteriol. 1988 Sep;170(9):4223-30. doi: 10.1128/jb.170.9.4223-4230.1988. J Bacteriol. 1988. PMID: 3045088 Free PMC article.
The organization of the SLT-IIv operon was similar to that of other members of the Shiga toxin family. Iron did not suppress SLT-IIv or SLT-II production, in contrast with its effect on Shiga toxin/SLT-I. Therefore, the regulation of synthesis of SLT-I …
The organization of the SLT-IIv operon was similar to that of other members of the Shiga toxin family. Iron did not suppress S …
Binding of shiga toxin 2e to porcine erythrocytes in vivo and in vitro.
Matise I, Cornick NA, Samuel JE, Moon HW. Matise I, et al. Among authors: samuel je. Infect Immun. 2003 Sep;71(9):5194-201. doi: 10.1128/IAI.71.9.5194-5201.2003. Infect Immun. 2003. PMID: 12933864 Free PMC article.
Shiga toxin 2e (Stx2e), produced by host-adapted Shiga toxin-producing Escherichia coli (STEC) strains, causes edema disease in weaned pigs. ...
Shiga toxin 2e (Stx2e), produced by host-adapted Shiga toxin-producing Escherichia coli (STEC) strains, causes e …
Evidence that proteolytic separation of Shiga-like toxin type IIv A subunit into A1 and A2 subunits is not required for toxin activity.
Samuel JE, Gordon VM. Samuel JE, et al. J Biol Chem. 1994 Feb 18;269(7):4853-9. J Biol Chem. 1994. PMID: 7906271 Free article.
The role for proteolytic activation of Shiga-like toxin type II variant (SLT-IIv) A subunit was examined using site-directed mutagenesis. ...Native toxin incubated with Vero cells was completely cleaved while only a fraction of R247H/R250H was cleaved. ...
The role for proteolytic activation of Shiga-like toxin type II variant (SLT-IIv) A subunit was examined using site-directed m …
Intervention with Shiga toxin (Stx) antibody after infection by Stx-producing Escherichia coli.
Matise I, Cornick NA, Booher SL, Samuel JE, Bosworth BT, Moon HW. Matise I, et al. Among authors: samuel je. J Infect Dis. 2001 Jan 15;183(2):347-350. doi: 10.1086/317930. Epub 2000 Dec 8. J Infect Dis. 2001. PMID: 11110647
Shiga toxins (Stxs) produced by Escherichia coli (STEC) cause systemic vascular damage, manifested as hemolytic uremic syndrome in humans and as edema disease in pigs. ...
Shiga toxins (Stxs) produced by Escherichia coli (STEC) cause systemic vascular damage, manifested as hemolytic uremic syndrome in hu …
Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants.
Samuel JE, Perera LP, Ward S, O'Brien AD, Ginsburg V, Krivan HC. Samuel JE, et al. Infect Immun. 1990 Mar;58(3):611-8. doi: 10.1128/iai.58.3.611-618.1990. Infect Immun. 1990. PMID: 2155181 Free PMC article.
The antigenically distinct Shiga-like toxins (SLTs) SLT-1 and SLT-II are cytotoxic for both Vero and HeLa cells and use Gal alpha 1-4Gal beta 1-4Glc beta 1-1Cer (Gb3) molecules as functional receptors. ...
The antigenically distinct Shiga-like toxins (SLTs) SLT-1 and SLT-II are cytotoxic for both Vero and HeLa cells and use Gal alpha 1-4 …
An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine.
Gordon VM, Whipp SC, Moon HW, O'Brien AD, Samuel JE. Gordon VM, et al. Among authors: samuel je. Infect Immun. 1992 Feb;60(2):485-90. doi: 10.1128/iai.60.2.485-490.1992. Infect Immun. 1992. PMID: 1730480 Free PMC article.
Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant (SLT-IIv). Pathology identical to that caused by ED can be duplicated in pigs that are injected with less than 10 ng of purified SLT-IIv per …
Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant …
Evaluation of the role of Shiga and Shiga-like toxins in mediating direct damage to human vascular endothelial cells.
Tesh VL, Samuel JE, Perera LP, Sharefkin JB, O'Brien AD. Tesh VL, et al. Among authors: samuel je. J Infect Dis. 1991 Aug;164(2):344-52. doi: 10.1093/infdis/164.2.344. J Infect Dis. 1991. PMID: 1649877
Infection with Shiga toxin- and Shiga-like toxin-producing strains of Shigella dysenteriae and Escherichia coli, respectively, can progress to the hemolytic-uremic syndrome. ...Shiga toxin was the predominant cytotoxic factor. Lipopolysac …
Infection with Shiga toxin- and Shiga-like toxin-producing strains of Shigella dysenteriae and Escherichia coli, …
19 results