Sandig V - Search Results

1

Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α₁-antitrypsin production in human AGE1.HN cells.

Niklas J, Nonnenmacher Y, Rose T, Sandig V, Heinzle E. Niklas J, et al. Among authors: sandig v. Appl Microbiol Biotechnol. 2012 Apr;94(1):57-67. doi: 10.1007/s00253-011-3811-4. Epub 2011 Dec 28. Appl Microbiol Biotechnol. 2012. PMID: 22202969

2

Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis.

Niklas J, Schräder E, Sandig V, Noll T, Heinzle E. Niklas J, et al. Among authors: sandig v. Bioprocess Biosyst Eng. 2011 Jun;34(5):533-45. doi: 10.1007/s00449-010-0502-y. Epub 2010 Dec 25. Bioprocess Biosyst Eng. 2011. PMID: 21188421 Free PMC article.

3

Primary metabolism in the new human cell line AGE1.HN at various substrate levels: increased metabolic efficiency and α1-antitrypsin production at reduced pyruvate load.

Niklas J, Priesnitz C, Rose T, Sandig V, Heinzle E. Niklas J, et al. Among authors: sandig v. Appl Microbiol Biotechnol. 2012 Feb;93(4):1637-50. doi: 10.1007/s00253-011-3526-6. Epub 2011 Aug 14. Appl Microbiol Biotechnol. 2012. PMID: 21842438

4

Metabolite channeling and compartmentation in the human cell line AGE1.HN determined by 13C labeling experiments and 13C metabolic flux analysis.

Niklas J, Sandig V, Heinzle E. Niklas J, et al. Among authors: sandig v. J Biosci Bioeng. 2011 Dec;112(6):616-23. doi: 10.1016/j.jbiosc.2011.07.021. Epub 2011 Aug 23. J Biosci Bioeng. 2011. PMID: 21865082

5

Metabolic flux rearrangement in the amino acid metabolism reduces ammonia stress in the α1-antitrypsin producing human AGE1.HN cell line.

Priesnitz C, Niklas J, Rose T, Sandig V, Heinzle E. Priesnitz C, et al. Among authors: sandig v. Metab Eng. 2012 Mar;14(2):128-37. doi: 10.1016/j.ymben.2012.01.001. Epub 2012 Jan 25. Metab Eng. 2012. PMID: 22289170

6

Biosynthetic pathway deflection - a new cell line engineering approach.

von Horsten HH, Rose T, Sandig V. von Horsten HH, et al. Among authors: sandig v. BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):O4. doi: 10.1186/1753-6561-5-S8-O4. eCollection 2011. BMC Proc. 2011. PMID: 22373289 Free PMC article. No abstract available.

7

Toolbox approach for fast generation of stable CHO production cell lines from different hosts.

Seitz S, von Horsten H, Rose T, Sandig V, Winkler K. Seitz S, et al. Among authors: sandig v. BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):P28. doi: 10.1186/1753-6561-5-S8-P28. eCollection 2011. BMC Proc. 2011. PMID: 22373322 Free PMC article. No abstract available.

8

Compartmentation and channelling of metabolites in the human cell line AGE1.HN(®).

Niklas J, Sandig V, Heinzle E. Niklas J, et al. Among authors: sandig v. BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):P84. doi: 10.1186/1753-6561-5-S8-P84. eCollection 2011. BMC Proc. 2011. PMID: 22373369 Free PMC article. No abstract available.

9

Producer vs. parental cell - metabolic changes and burden upon α1-antitrypsin production in AGE1.HN(®).

Niklas J, Priesnitz C, Sandig V, Rose T, Heinzle E. Niklas J, et al. Among authors: sandig v. BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):P85. doi: 10.1186/1753-6561-5-S8-P85. eCollection 2011. BMC Proc. 2011. PMID: 22373391 Free PMC article. No abstract available.

10

Characterisation of cultivation of the human cell line AGE1.HN.AAT.

Schräder E, Scholz S, Niklas J, Rath A, Barradas OP, Jandt U, Sandig V, Rose T, Pörtner R, Reichl U, Zeng AP, Heinzle E, Noll T. Schräder E, et al. Among authors: sandig v. BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):P87. doi: 10.1186/1753-6561-5-S8-P87. eCollection 2011. BMC Proc. 2011. PMID: 22373444 Free PMC article. No abstract available.

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