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Individuals with isolated congenital GH deficiency due to a GHRH receptor gene mutation appear to cope better with SARS-CoV-2 infection than controls.
Melo MA, Borges LP, Salvatori R, Souza DRV, Santos-Júnior HT, de R Neto JM, Campos VC, Santos AA, Oliveira CRP, da Invenção GB, Batista VO, Matos ILS, Barros-Oliveira CS, Dos Santos KA, Santos EG, Souza NAA, Melo EV, Borges PC, Santos SEFS, de Oliveira BM, Oliveira-Santos AA, de Jesus AR, Aguiar-Oliveira MH. Melo MA, et al. Among authors: santos aa, santos eg, santos junior ht, santos sefs. Endocrine. 2021 May;72(2):349-355. doi: 10.1007/s12020-021-02728-8. Epub 2021 Apr 16. Endocrine. 2021. PMID: 33860882 Free PMC article.
Longevity in untreated congenital growth hormone deficiency due to a homozygous mutation in the GHRH receptor gene.
Aguiar-Oliveira MH, Oliveira FT, Pereira RM, Oliveira CR, Blackford A, Valenca EH, Santos EG, Gois-Junior MB, Meneguz-Moreno RA, Araujo VP, Oliveira-Neto LA, Almeida RP, Santos MA, Farias NT, Silveira DC, Cabral GW, Calazans FR, Seabra JD, Lopes TF, Rodrigues EO, Porto LA, Oliveira IP, Melo EV, Martari M, Salvatori R. Aguiar-Oliveira MH, et al. Among authors: santos eg, santos ma. J Clin Endocrinol Metab. 2010 Feb;95(2):714-21. doi: 10.1210/jc.2009-1879. Epub 2009 Dec 4. J Clin Endocrinol Metab. 2010. PMID: 19965916 Free PMC article.
Lifetime congenital isolated GH deficiency does not protect from the development of diabetes.
Vicente TA, Rocha IE, Salvatori R, Oliveira CR, Pereira RM, Souza AH, Campos VC, Santos EG, Diniz RD, Valença EH, Epitácio-Pereira CC, Oliveira MC, Mari A, Aguiar-Oliveira MH. Vicente TA, et al. Among authors: santos eg. Endocr Connect. 2013 Jun 15;2(2):112-7. doi: 10.1530/EC-13-0014. Print 2013 Jun 1. Endocr Connect. 2013. PMID: 23795286 Free PMC article.
Isolated GH deficiency due to a GHRH receptor mutation causes hip joint problems and genu valgum, and reduces size but not density of trabecular and mixed bone.
Epitácio-Pereira CC, Silva GM, Salvatori R, Santana JA, Pereira FA, Gois-Junior MB, Britto AV, Oliveira CR, Souza AH, Santos EG, Campos VC, Pereira RM, Valença EH, Barbosa RA, Farias MI, de Paula FJ, Ribeiro TV, Oliveira MC, Aguiar-Oliveira MH. Epitácio-Pereira CC, et al. Among authors: santos eg. J Clin Endocrinol Metab. 2013 Nov;98(11):E1710-5. doi: 10.1210/jc.2013-2349. Epub 2013 Sep 20. J Clin Endocrinol Metab. 2013. PMID: 24057284
Older individuals heterozygous for a growth hormone-releasing hormone receptor gene mutation are shorter than normal subjects.
Aguiar-Oliveira MH, Cardoso-Filho MA, Pereira RM, Oliveira CR, Souza AH, Santos EG, Campos VC, Valença EH, de Oliveira FT, Oliveira-Neto LA, Gois-Junior MB, Oliveira-Santos AA, Salvatori R. Aguiar-Oliveira MH, et al. Among authors: santos eg. J Hum Genet. 2015 Jun;60(6):335-8. doi: 10.1038/jhg.2015.25. Epub 2015 Mar 12. J Hum Genet. 2015. PMID: 25761575
Evolution to permanent or transient conditions in children with positive neonatal TSH screening tests in Sergipe, Brazil.
Matos DM, Ramalho RJ, Carvalho BM, Almeida MA, Passos LF, Vasconcelos TT, Melo EV, Oliveira CR, Santos EG, Resende KF, Aguiar-Oliveira MH. Matos DM, et al. Among authors: santos eg. Arch Endocrinol Metab. 2016 Oct;60(5):450-456. doi: 10.1590/2359-3997000000189. Epub 2016 Aug 25. Arch Endocrinol Metab. 2016. PMID: 27812608 Free PMC article.
Occurrence of neoplasms in individuals with congenital, severe GH deficiency from the Itabaianinha kindred.
Marinho CG, Mermejo LM, Salvatori R, Assirati JA Junior, Oliveira CRP, Santos EG, Leal ÂCGB, Barros-Oliveira CS, Damascena NP, Lima CA, Farias CT, Moreira AC, Aguiar-Oliveira MH. Marinho CG, et al. Among authors: santos eg. Growth Horm IGF Res. 2018 Aug;41:71-74. doi: 10.1016/j.ghir.2018.03.004. Epub 2018 Mar 12. Growth Horm IGF Res. 2018. PMID: 29571594
Enteroendocrine Connections in Congenital Isolated GH Deficiency Due to a GHRH Receptor Gene Mutation.
Oliveira-Santos AA, Salvatori R, Nogueira MC, Bueno AC, Barros-Oliveira CS, Leal ÂCGB, Marinho CG, Damascena NP, Oliveira DA, Melo MA, Oliveira CRP, da Costa FO, Dos Santos JSS, Santos PFC, Campos VC, Santos EG, Melo EV, Barbosa MLA, Rocha IES, de Castro M, Aguiar-Oliveira MH. Oliveira-Santos AA, et al. Among authors: santos eg, santos pfc. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2777-2784. doi: 10.1210/jc.2019-00094. J Clin Endocrinol Metab. 2019. PMID: 30860584
128 results