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Tubulin polymerization promoting protein 1 (Tppp1) phosphorylation by Rho-associated coiled-coil kinase (rock) and cyclin-dependent kinase 1 (Cdk1) inhibits microtubule dynamics to increase cell proliferation.
Schofield AV, Gamell C, Suryadinata R, Sarcevic B, Bernard O. Schofield AV, et al. Among authors: sarcevic b. J Biol Chem. 2013 Mar 15;288(11):7907-7917. doi: 10.1074/jbc.M112.441048. Epub 2013 Jan 25. J Biol Chem. 2013. PMID: 23355470 Free PMC article.
Cdk5 is essential for synaptic vesicle endocytosis.
Tan TC, Valova VA, Malladi CS, Graham ME, Berven LA, Jupp OJ, Hansra G, McClure SJ, Sarcevic B, Boadle RA, Larsen MR, Cousin MA, Robinson PJ. Tan TC, et al. Among authors: sarcevic b. Nat Cell Biol. 2003 Aug;5(8):701-10. doi: 10.1038/ncb1020. Nat Cell Biol. 2003. PMID: 12855954
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