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Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9.
Li HL, Fujimoto N, Sasakawa N, Shirai S, Ohkame T, Sakuma T, Tanaka M, Amano N, Watanabe A, Sakurai H, Yamamoto T, Yamanaka S, Hotta A. Li HL, et al. Among authors: sasakawa n. Stem Cell Reports. 2015 Jan 13;4(1):143-154. doi: 10.1016/j.stemcr.2014.10.013. Epub 2014 Nov 26. Stem Cell Reports. 2015. PMID: 25434822 Free PMC article.
CRISPR-Cas3 induces broad and unidirectional genome editing in human cells.
Morisaka H, Yoshimi K, Okuzaki Y, Gee P, Kunihiro Y, Sonpho E, Xu H, Sasakawa N, Naito Y, Nakada S, Yamamoto T, Sano S, Hotta A, Takeda J, Mashimo T. Morisaka H, et al. Among authors: sasakawa n. Nat Commun. 2019 Dec 6;10(1):5302. doi: 10.1038/s41467-019-13226-x. Nat Commun. 2019. PMID: 31811138 Free PMC article.
Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping.
Gee P, Lung MSY, Okuzaki Y, Sasakawa N, Iguchi T, Makita Y, Hozumi H, Miura Y, Yang LF, Iwasaki M, Wang XH, Waller MA, Shirai N, Abe YO, Fujita Y, Watanabe K, Kagita A, Iwabuchi KA, Yasuda M, Xu H, Noda T, Komano J, Sakurai H, Inukai N, Hotta A. Gee P, et al. Among authors: sasakawa n. Nat Commun. 2020 Mar 13;11(1):1334. doi: 10.1038/s41467-020-14957-y. Nat Commun. 2020. PMID: 32170079 Free PMC article.
Humanin derivative, HNG, enhances neurotransmitter release.
Ikegawa N, Kozuka A, Morita N, Murakami M, Sasakawa N, Niikura T. Ikegawa N, et al. Among authors: sasakawa n. Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130204. doi: 10.1016/j.bbagen.2022.130204. Epub 2022 Jul 16. Biochim Biophys Acta Gen Subj. 2022. PMID: 35843407
54 results