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Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.
Czimmerer Z, Nagy ZS, Nagy G, Horvath A, Silye-Cseh T, Kriston A, Jonas D, Sauer S, Steiner L, Daniel B, Deleuze JF, Nagy L. Czimmerer Z, et al. Among authors: sauer s. Mol Cell Endocrinol. 2018 Aug 15;471:63-74. doi: 10.1016/j.mce.2017.07.034. Epub 2017 Jul 31. Mol Cell Endocrinol. 2018. PMID: 28774779
OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation.
Simandi Z, Horvath A, Wright LC, Cuaranta-Monroy I, De Luca I, Karolyi K, Sauer S, Deleuze JF, Gudas LJ, Cowley SM, Nagy L. Simandi Z, et al. Among authors: sauer s. Mol Cell. 2016 Aug 18;63(4):647-661. doi: 10.1016/j.molcel.2016.06.039. Epub 2016 Aug 4. Mol Cell. 2016. PMID: 27499297 Free article.
The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.
Czimmerer Z, Daniel B, Horvath A, Rückerl D, Nagy G, Kiss M, Peloquin M, Budai MM, Cuaranta-Monroy I, Simandi Z, Steiner L, Nagy B Jr, Poliska S, Banko C, Bacso Z, Schulman IG, Sauer S, Deleuze JF, Allen JE, Benko S, Nagy L. Czimmerer Z, et al. Among authors: sauer s. Immunity. 2018 Jan 16;48(1):75-90.e6. doi: 10.1016/j.immuni.2017.12.010. Immunity. 2018. PMID: 29343442 Free PMC article.
The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.
Daniel B, Nagy G, Czimmerer Z, Horvath A, Hammers DW, Cuaranta-Monroy I, Poliska S, Tzerpos P, Kolostyak Z, Hays TT, Patsalos A, Houtman R, Sauer S, Francois-Deleuze J, Rastinejad F, Balint BL, Sweeney HL, Nagy L. Daniel B, et al. Among authors: sauer s. Immunity. 2018 Oct 16;49(4):615-626.e6. doi: 10.1016/j.immuni.2018.09.005. Immunity. 2018. PMID: 30332629 Free PMC article.
The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel B, Czimmerer Z, Halasz L, Boto P, Kolostyak Z, Poliska S, Berger WK, Tzerpos P, Nagy G, Horvath A, Hajas G, Cseh T, Nagy A, Sauer S, Francois-Deleuze J, Szatmari I, Bacsi A, Nagy L. Daniel B, et al. Among authors: sauer s. Genes Dev. 2020 Nov 1;34(21-22):1474-1492. doi: 10.1101/gad.343038.120. Epub 2020 Oct 15. Genes Dev. 2020. PMID: 33060136 Free PMC article.
PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology.
Simandi Z, Czipa E, Horvath A, Koszeghy A, Bordas C, Póliska S, Juhász I, Imre L, Szabó G, Dezso B, Barta E, Sauer S, Karolyi K, Kovacs I, Hutóczki G, Bognár L, Klekner Á, Szucs P, Bálint BL, Nagy L. Simandi Z, et al. Among authors: sauer s. Stem Cells. 2015 Mar;33(3):726-41. doi: 10.1002/stem.1894. Stem Cells. 2015. PMID: 25388207 Free article.
Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients.
Llewellyn MS, Messenger LA, Luquetti AO, Garcia L, Torrico F, Tavares SB, Cheaib B, Derome N, Delepine M, Baulard C, Deleuze JF, Sauer S, Miles MA. Llewellyn MS, et al. Among authors: sauer s. PLoS Negl Trop Dis. 2015 Apr 7;9(4):e0003458. doi: 10.1371/journal.pntd.0003458. eCollection 2015 Apr. PLoS Negl Trop Dis. 2015. PMID: 25849488 Free PMC article.
Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone.
Tolkachov A, Fischer C, Ambrosi TH, Bothe M, Han CT, Muenzner M, Mathia S, Salminen M, Seifert G, Thiele M, Duda GN, Meijsing SH, Sauer S, Schulz TJ, Schupp M. Tolkachov A, et al. Among authors: sauer s. Mol Cell Biol. 2018 May 29;38(12):e00599-17. doi: 10.1128/MCB.00599-17. Print 2018 Jun 15. Mol Cell Biol. 2018. PMID: 29581184 Free PMC article.
627 results