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HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma.
Jacobson C, Kopp N, Layer JV, Redd RA, Tschuri S, Haebe S, van Bodegom D, Bird L, Christie AL, Christodoulou A, Saur A, Tivey T, Zapf S, Bararia D, Zimber-Strobl U, Rodig SJ, Weigert O, Weinstock DM. Jacobson C, et al. Blood. 2016 Nov 24;128(21):2517-2526. doi: 10.1182/blood-2016-04-711176. Epub 2016 Oct 14. Blood. 2016. PMID: 27742706 Free article.
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
Chen Z, Cheng K, Walton Z, Wang Y, Ebi H, Shimamura T, Liu Y, Tupper T, Ouyang J, Li J, Gao P, Woo MS, Xu C, Yanagita M, Altabef A, Wang S, Lee C, Nakada Y, Peña CG, Sun Y, Franchetti Y, Yao C, Saur A, Cameron MD, Nishino M, Hayes DN, Wilkerson MD, Roberts PJ, Lee CB, Bardeesy N, Butaney M, Chirieac LR, Costa DB, Jackman D, Sharpless NE, Castrillon DH, Demetri GD, Jänne PA, Pandolfi PP, Cantley LC, Kung AL, Engelman JA, Wong KK. Chen Z, et al. Nature. 2012 Mar 18;483(7391):613-7. doi: 10.1038/nature10937. Nature. 2012. PMID: 22425996 Free PMC article.