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Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.
Lynch CJ, Bernad R, Martínez-Val A, Shahbazi MN, Nóbrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Ginés L, Alcazar N, Graña-Castro O, Gómez-Lopez G, Aksoy I, Muñoz-Martín M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Muñoz J, Zernicka-Goetz M, Serrano M. Lynch CJ, et al. Among authors: savatier p. Nat Cell Biol. 2020 Oct;22(10):1223-1238. doi: 10.1038/s41556-020-0573-1. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989249 Free article.
A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency.
Coronado D, Godet M, Bourillot PY, Tapponnier Y, Bernat A, Petit M, Afanassieff M, Markossian S, Malashicheva A, Iacone R, Anastassiadis K, Savatier P. Coronado D, et al. Among authors: savatier p. Stem Cell Res. 2013 Jan;10(1):118-31. doi: 10.1016/j.scr.2012.10.004. Epub 2012 Oct 29. Stem Cell Res. 2013. PMID: 23178806 Free article.
Cell cycle features of primate embryonic stem cells.
Fluckiger AC, Marcy G, Marchand M, Négre D, Cosset FL, Mitalipov S, Wolf D, Savatier P, Dehay C. Fluckiger AC, et al. Among authors: savatier p. Stem Cells. 2006 Mar;24(3):547-56. doi: 10.1634/stemcells.2005-0194. Epub 2005 Oct 20. Stem Cells. 2006. PMID: 16239321 Free PMC article.
Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency.
Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, Rognard C, Hochard A, Voisin S, Fontaine E, Mure M, Afanassieff M, Cleroux E, Guibert S, Chen J, Vallot C, Acloque H, Genthon C, Donnadieu C, De Vos J, Sanlaville D, Guérin JF, Weber M, Stanton LW, Rougeulle C, Pain B, Bourillot PY, Savatier P. Chen H, et al. Among authors: savatier p. Nat Commun. 2015 May 13;6:7095. doi: 10.1038/ncomms8095. Nat Commun. 2015. PMID: 25968054 Free PMC article.
68 results